The aim of the present study was to determine the spleen cytoarchitecture in alpacafetuses of different stages of development. Sixteen alpaca fetuses were obtained fromfemale alpacas slaughtered in the central highlands of Peru. The fetuses were distributedin six groups according to their fetal age (55, 100, 120, 150, 180, and 200 days). Spleens were dissected and samples were stained with hematoxylin-eosin (cellular distribution),Masson ́s trichrome (collagen and muscle fibers), and periodic acid Schiff for argenticimpregnation (reticular fibers) for histological evaluation. Macroscopically, the spleen at55 days of age is slightly outlined, at 120 days is lobed with a triangular shape and at 150days had the appearance of the mature animal. Microscopically, at 55 days there is apredominance of transitional embryonic connective tissue to reticular tissue and somelymphoid cells are locate...

The aim of the present study was to determine the spleen cytoarchitecture in alpacafetuses of different stages of development. Sixteen alpaca fetuses were obtained fromfemale alpacas slaughtered in the central highlands of Peru. The fetuses were distributedin six groups according to their fetal age (55, 100, 120, 150, 180, and 200 days). Spleens were dissected and samples were stained with hematoxylin-eosin (cellular distribution),Masson ́s trichrome (collagen and muscle fibers), and periodic acid Schiff for argenticimpregnation (reticular fibers) for histological evaluation. Macroscopically, the spleen at55 days of age is slightly outlined, at 120 days is lobed with a triangular shape and at 150days had the appearance of the mature animal. Microscopically, at 55 days there is apredominance of transitional embryonic connective tissue to reticular tissue and somelymphoid cells are locate...