The feasibility of untreated bovine pericardium xenograft as biomaterial for the lining of the small intestine anastomosis in horses to avoid dehiscences, leakage, fistulas and formation of adhesions in the postoperative period was investigated. Seven horses were submitted to end-to-end jejunal anastomosis coated with untreated bovine pericardial xenograft and a control group of seven horses submitted to end-to-end jejunal anastomosis only. Postoperative pain, cellular components and organoleptic characteristics of the peritoneal fluid were evaluated. It was found that the bovine pericardium xenograft coating does not generate significant differences in the quantification of pain (postoperative colic) nor in the total nucleated cell count of the peritoneal fluid nor does it influence the alterations of the color, turbidity and smell of the peritoneal fluid, demonstrating that untreated b...

The evaluation of the untreated bovine pericardium xenograft as a biomaterial for the lining of the small intestine anastomosis in equines was conducted. Seven horses with ages between 3 and 10 years were operated on. Two of them were randomly selected, doing a laparotomy to one of them at 15 days and the other at 100 days post-surgery. In the macroscopic and histopathological studies of the cicatricial area of the end-to-end anastomosis it was evidenced that the xenograft does not contract or move from the line of suture, guaranteeing the process of cicatricial remodeling and avoiding complications such as peritonitis, stenosis, abscesses, anastomotic leakage and adhesions. It is concluded that the untreated bovine pericardium xenograft is viable and effective as a jejunal enterectomy lining, showing good adaptability as a natural microenvironment for progenitor cells responsible for ci...

Se investigó la viabilidad del xenoinjerto de pericardio bovino no tratado como biomaterial para el revestimiento de la anastomosis de intestino delgado en equinos a fin de evitar dehiscencias, fugas, fístulas y formación de adherencias en el posoperatorio. Se trabajó con siete equinos sometidos a anastomosis término-terminal yeyunal revestida con xenoinjerto de pericardio bovino no tratado y un grupo control de siete equinos sometidos solamente a anastomosis término-terminal yeyunal. Se evaluó el dolor postoperatorio, los componentes celulares y las características organolépticas del líquido peritoneal. Se encontró que el revestimiento con xenoinjerto de pericardio bovino no genera diferencias significativas en la cuantificación del dolor (cólico posoperatorio) ni en el recuento total de células nucleadas del líquido peritoneal, ni influye en las alteraciones del color, t...

Se hizo la evaluación del xenoinjerto de pericardio bovino no tratado como biomaterial para el revestimiento de la anastomosis de intestino delgado en equinos. Se practicó la cirugía a siete equinos con edades entre 3 y 10 años. Se seleccionaron al azar a dos de ellos, haciendo una laparatomía a uno de ellos a los 15 días y al otro a los 100 días del posoperatorio. En los estudios macroscópicos e histopatológicos de la zona cicatricial de la anastomosis término-terminal se evidenció que el xenoinjerto no se contrae ni se desplaza de la línea de sutura, garantizando el proceso de remodelación cicatricial y evitando complicaciones como peritonitis, estenosis, abscesos, fugas anastomóticas y adherencias. Se concluye que el xenoinjerto de pericardio bovino no tratado es viable y efectivo, como revestimiento de la enterectomía yeyunal; demostrando buena adaptabilidad como micro...

Postoperative complications after intestinal anastomosis remain the main concern in abdominal surgery in horses. The aim of this study was to describe an end-to-end jejunal anastomosis with a mesenteric flap covering technique and its macroscopic and postoperative histological characteristics. This technique is based on a reinforcement to the conventional surgery performed with a simple interrupted suture pattern to prevent postoperative complications. Five previously premedicated horses with xylazine 0.5 mg/kg, acepromazine 0.03 mg/kg and tramadol 2 mg/kg were induced to general anesthesia with diazepam 0.25 mg/kg and ketamine 2.2 mg/kg. General anesthesia was maintained with a minimum alveolar concentration of 1.4 ± 0.2% of isoflurane. A midline abdominal wall approach was made. A 10 cm jejunal segment was selected for resection and end-to-end anastomosis. A mesenteric flap large enou...