La existencia sincrónica del carcinoma papilar y medular es muy infrecuente, y pueden tener una presentación discreta o mixta. Aunque su patogénesis no está del todo clara, actualmente se han propuesto diversas teorías que involucran mutaciones genéticas, factores locales y factores ambientales en su aparición. De acuerdo con sus características histológicas, estas son muy variables, y presentan diferentes patrones estructurales. El abordaje terapéutico difiere en ambos tipos histopatológicos, por lo que es importante saber de la existencia sincrónica de estos tumores.

The synchronous existence of papillary and medullary carcinoma is infrequent, and they can have a discrete or mixed presentation. About its pathogenesis, it is not entirely clear, however, various theories have currently been proposed where genetic mutations and local and environmental factors involved in its appearance are involved. According to their histological characteristics, these are highly variable, presenting different structural patterns. The therapeutic approach differs in both histopathological types, so it is important to know about the synchronous existence of these tumors.

The synchronous existence of papillary and medullary carcinoma is infrequent, and they can have a discrete or mixed presentation. About its pathogenesis, it is not entirely clear, however, various theories have currently been proposed where genetic mutations and local and environmental factors involved in its appearance are involved. According to their histological characteristics, these are highly variable, presenting different structural patterns. The therapeutic approach differs in both histopathological types, so it is important to know about the synchronous existence of these tumors.

El melanoma anorrectal es un cáncer poco frecuente, de difícil diagnóstico, de alta malignidad y mal pronóstico. El tratamiento suele ser quirúrgico y suele incluir adyuvantes como radioterapia e inmunoterapia. Presentamos el caso de una peruana de 77 años que finalmente fue diagnosticada de este cáncer durante la pandemia de COVID-19, lo que complicó su tratamiento y permitió la propagación del cáncer. Su tratamiento incluyó resección abdominoperineal, linfadenectomía pélvica bilateral, rafia de vena ilíaca interna izquierda y colostomía terminal, seguida de radioterapia 3D (50 Gy, 25 sesiones) y tratamiento sistémico con nivolumab, todos los cuales fueron bien tolerados. La paciente estaba viva al 20 de agosto de 2023, habiendo sobrevivido durante más de 3 años desde el inicio de los síntomas

Gastric glomangiomas are rare vascular tumors originating from glomic cells. We report the case of a 52-year-old woman who presented with early satiety and discomfort in the upper abdomen. Initial biopsy and imaging studies suggested a gastrointestinal stromal tumor (GIST). The tumor was surgically removed through antrectomy and lymphadenectomy, ensuring clear surgical margins. However, immunohistochemistry and histopathological examination of the removed tissue revealed that the initial diagnosis was incorrect; the patient was found to have a gastric glomangioma. This case highlights the challenges in accurately diagnosing gastric glomus tumors before surgery and reviews the prognosis and available treatment options.