Helicobacter pylori and its relationship with variations of gut microbiota in asymptomatic children between 6 and 12 years

• Autores: Benavides-Ward, Araceli, Vasquez-Achaya, Fernando, Mazulis,Fernando, Urteaga, Numan, del Valle-Mendoza, Juana, Silva-Caso, Wilmer, Aguilar-Luis, Miguel Angel
• Formato: artículo
• Fecha de Publicación: 2018
• Institución: Universidad Peruana de Ciencias Aplicadas
• Repositorio: UPC-Institucional
• Lenguaje: inglés
• OAI Identifier: oai:repositorioacademico.upc.edu.pe:10757/624618
• Enlace del recurso: https://doi.org/10.1186/s13104-018-3565-5; http://hdl.handle.net/10757/624618
• Nivel de acceso: acceso abierto
• Materia: Gut microbiota; Helicobacter pylori; Peru; School children

Objective: To determine the variations in the composition of the intestinal microbiota in asymptomatic children infected with Helicobacter pylori in comparison with children without the infection. Results: Children infected with H. pylori doubled their probability of presenting 3 of 9 genera of bacteria from the gut microbiota, including: Proteobacteria (p = 0.008), Clostridium (p = 0.040), Firmicutes (p = 0.001) and Prevotella (p = 0.006) in comparison to patients without the infection. We performed a nutritional assessment and found that growth stunting was statistically significantly higher in patients infected with H. pylori (p = 0.046).