Association between free thyroid hormones values and the lipid profile in middle-aged women with chronic symptoms

Descripción del Articulo

El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado.
Detalles Bibliográficos
Autores: Guarnizo-Poma, Mirella, Paico-Palacios, Socorro, Pantoja-Torres, Betzi, Lazaro-Alcantara, Herbert, Urrunaga-Pastor, Diego, Benítes-Zapata, Vicente A.
Formato: artículo
Fecha de Publicación:2018
Institución:Universidad Peruana de Ciencias Aplicadas
Repositorio:UPC-Institucional
Lenguaje:inglés
OAI Identifier:oai:repositorioacademico.upc.edu.pe:10757/624620
Enlace del recurso:http://hdl.handle.net/10757/624620
Nivel de acceso:acceso embargado
Materia:Cholesterol, LDL
Dyslipidemias
Thyroid
Triiodothyronine
Women
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dc.title.en_US.fl_str_mv Association between free thyroid hormones values and the lipid profile in middle-aged women with chronic symptoms
title Association between free thyroid hormones values and the lipid profile in middle-aged women with chronic symptoms
spellingShingle Association between free thyroid hormones values and the lipid profile in middle-aged women with chronic symptoms
Guarnizo-Poma, Mirella
Cholesterol, LDL
Dyslipidemias
Thyroid
Triiodothyronine
Women
title_short Association between free thyroid hormones values and the lipid profile in middle-aged women with chronic symptoms
title_full Association between free thyroid hormones values and the lipid profile in middle-aged women with chronic symptoms
title_fullStr Association between free thyroid hormones values and the lipid profile in middle-aged women with chronic symptoms
title_full_unstemmed Association between free thyroid hormones values and the lipid profile in middle-aged women with chronic symptoms
title_sort Association between free thyroid hormones values and the lipid profile in middle-aged women with chronic symptoms
author Guarnizo-Poma, Mirella
author_facet Guarnizo-Poma, Mirella
Paico-Palacios, Socorro
Pantoja-Torres, Betzi
Lazaro-Alcantara, Herbert
Urrunaga-Pastor, Diego
Benítes-Zapata, Vicente A.
author_role author
author2 Paico-Palacios, Socorro
Pantoja-Torres, Betzi
Lazaro-Alcantara, Herbert
Urrunaga-Pastor, Diego
Benítes-Zapata, Vicente A.
author2_role author
author
author
author
author
dc.contributor.email.es_PE.fl_str_mv mguarnizo@imm.com.pe
dc.contributor.author.fl_str_mv Guarnizo-Poma, Mirella
Paico-Palacios, Socorro
Pantoja-Torres, Betzi
Lazaro-Alcantara, Herbert
Urrunaga-Pastor, Diego
Benítes-Zapata, Vicente A.
dc.subject.en_US.fl_str_mv Cholesterol, LDL
Dyslipidemias
Thyroid
Triiodothyronine
Women
topic Cholesterol, LDL
Dyslipidemias
Thyroid
Triiodothyronine
Women
description El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado.
publishDate 2018
dc.date.accessioned.none.fl_str_mv 2018-11-23T20:53:48Z
dc.date.available.none.fl_str_mv 2018-11-23T20:53:48Z
dc.date.issued.fl_str_mv 2018-07
dc.type.en_US.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.issn.none.fl_str_mv 18714021
dc.identifier.doi.none.fl_str_mv 10.1016/j.dsx.2018.03.023
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10757/624620
dc.identifier.journal.en_US.fl_str_mv Diabetes and Metabolic Syndrome: Clinical Research and Reviews
dc.identifier.isni.none.fl_str_mv 0000 0001 2196 144X
identifier_str_mv 18714021
10.1016/j.dsx.2018.03.023
Diabetes and Metabolic Syndrome: Clinical Research and Reviews
0000 0001 2196 144X
url http://hdl.handle.net/10757/624620
dc.language.iso.en_US.fl_str_mv eng
language eng
dc.relation.url.en_US.fl_str_mv https://linkinghub.elsevier.com/retrieve/pii/S1871402118300560
dc.rights.en_US.fl_str_mv info:eu-repo/semantics/embargoedAccess
eu_rights_str_mv embargoedAccess
dc.format.en_US.fl_str_mv application/pdf
dc.publisher.en_US.fl_str_mv Elsevier Ltd
dc.source.es_PE.fl_str_mv Universidad Peruana de Ciencias Aplicadas (UPC)
Repositorio Academico - UPC
dc.source.none.fl_str_mv reponame:UPC-Institucional
instname:Universidad Peruana de Ciencias Aplicadas
instacron:UPC
instname_str Universidad Peruana de Ciencias Aplicadas
instacron_str UPC
institution UPC
reponame_str UPC-Institucional
collection UPC-Institucional
dc.source.journaltitle.none.fl_str_mv Diabetes & Metabolic Syndrome: Clinical Research & Reviews
dc.source.volume.none.fl_str_mv 12
dc.source.issue.none.fl_str_mv 4
dc.source.beginpage.none.fl_str_mv 531
dc.source.endpage.none.fl_str_mv 535
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spelling 37046881d08c72ebbfab942c37e1fb98-12cc9aa17c4f9246022c95244af4a629c-115667af7e6363d0f591d2f243aa99411-1e47f658e17f0ff9c68f84f451efef3b7-11b46942249e1da47206b7ce03f249a14-11252d461f45efe4dc7eec4d8ea6f5c0eGuarnizo-Poma, MirellaPaico-Palacios, SocorroPantoja-Torres, BetziLazaro-Alcantara, HerbertUrrunaga-Pastor, DiegoBenítes-Zapata, Vicente A.mguarnizo@imm.com.pe2018-11-23T20:53:48Z2018-11-23T20:53:48Z2018-071871402110.1016/j.dsx.2018.03.023http://hdl.handle.net/10757/624620Diabetes and Metabolic Syndrome: Clinical Research and Reviews0000 0001 2196 144XEl texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado.Aims: To determine the association between the thyroid hormones(FT3, FT4 and TSH) and the lipid profile markers(HDL-c, LDL-c and triglycerides) values in middle-aged women with no metabolic disorders and recurrent chronic symptomatology. Materials and Methods: We carried out an analytical cross-sectional study in euthyroid women with recurrent chronic symptoms of at least six months with no apparent diagnosis who attended the endocrinological gynaecology outpatient service of a private clinic in Lima-Peru during 2012–2014. Participants who met the eligibility criteria were evaluated according to their thyroid hormones(FT3, FT4 and TSH) and lipid profile markers(HDL-c, LDL-c and triglycerides) values. We elaborated univariate/multivariate linear regression models to evaluate the association between the thyroid markers and the lipid profile levels. The reported association measure was the beta coefficient(β) with its respective p-value. Results: We analyzed 211 participants, the average age was 44.9 ± 14.0(SD) years, the FT3 and FT4 mean levels were 3.2 ± 0.4 pg/mL and 1.2 ± 0.2 ng/dL respectively, while the TSH median was 2.8(IQR:1.9–4.0) μU/mL. The mean or median levels of LDL-c, HDL-c and triglycerides were of 137.5 ± 37.9 mg/dL, 54.0 ± 15.0 mg/dL and 118.5(IQR:79.5–169.5) mg/dL respectively. In the multivariate linear regression model between the FT3 and LDL-c levels, we found that for each increase in a FT3 unit, the LDL-c values decreased on average 30.85 mg/dL(p < 0.01). We found no statistically significant associations in the other multivariate models of linear regression, among the other thyroid hormones and lipid markers. Conclusion: We found an inverse association between the FT3 and LDL-c values in women with chronic gynaecological symptomsRevisión por paresRevisión por paresapplication/pdfengElsevier Ltdhttps://linkinghub.elsevier.com/retrieve/pii/S1871402118300560info:eu-repo/semantics/embargoedAccessUniversidad Peruana de Ciencias Aplicadas (UPC)Repositorio Academico - UPCDiabetes & Metabolic Syndrome: Clinical Research & Reviews124531535reponame:UPC-Institucionalinstname:Universidad Peruana de Ciencias Aplicadasinstacron:UPCCholesterol, LDLDyslipidemiasThyroidTriiodothyronineWomenAssociation between free thyroid hormones values and the lipid profile in middle-aged women with chronic symptomsinfo:eu-repo/semantics/article2018-11-23T20:58:07ZTHUMBNAIL10.1016 j.dsx.2018.03.023.pdf.jpg10.1016 j.dsx.2018.03.023.pdf.jpgGenerated Thumbnailimage/jpeg88675https://repositorioacademico.upc.edu.pe/bitstream/10757/624620/4/10.1016%20j.dsx.2018.03.023.pdf.jpgbc858944a536c848d859d31b30a8d2c6MD54falseelsevier-thumbnail.pngapplication/octet-stream55422https://repositorioacademico.upc.edu.pe/bitstream/10757/624620/5/elsevier-thumbnail.pngfc9b2fb2bcf42cc457e6bb7a20eac582MD55falseTEXT10.1016 j.dsx.2018.03.023.pdf.txt10.1016 j.dsx.2018.03.023.pdf.txtExtracted texttext/plain3548https://repositorioacademico.upc.edu.pe/bitstream/10757/624620/3/10.1016%20j.dsx.2018.03.023.pdf.txtda51d795dcba5f77226bc26ddba6e51cMD53falseORIGINAL10.1016 j.dsx.2018.03.023.pdf10.1016 j.dsx.2018.03.023.pdfapplication/pdf219705https://repositorioacademico.upc.edu.pe/bitstream/10757/624620/2/10.1016%20j.dsx.2018.03.023.pdfd8b8e1e0ba7e8e31ed1dc95924caec7eMD52trueLICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorioacademico.upc.edu.pe/bitstream/10757/624620/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51false10757/624620oai:repositorioacademico.upc.edu.pe:10757/6246202020-04-06 16:25:19.548Repositorio académico upcupc@openrepository.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Association between free thyroid hormones values and the lipid profile in middle-aged women with chronic symptoms
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