Factores de riesgo asociados a mortalidad en pacientes con COVID-19 en el Hospital Regional de Loreto, Perú 2021

• Autor: Alván Rodríguez, Elsa Día
• Formato: tesis de grado
• Fecha de Publicación: 2022
• Institución: Universidad Nacional De La Amazonía Peruana
• Repositorio: UNAPIquitos-Institucional
• Lenguaje: español
• OAI Identifier: oai:repositorio.unapiquitos.edu.pe:20.500.12737/8314
• Enlace del recurso: https://hdl.handle.net/20.500.12737/8314
• Nivel de acceso: acceso abierto
• Materia: Covid-19; Mortalidad; Factores de riesgo; Pacientes ambulatorios; Hospitales públicos; https://purl.org/pe-repo/ocde/ford#3.03.08

Objective: To determine the risk factors associated with mortality in patients with COVID-19 at the Regional Hospital of Loreto, Peru 2021. Methodology and materials: Retrospective analytical observational case-control study of adult patients hospitalized for COVID-19 from January to May 2021. Sociodemographic data, comorbidities and laboratory tests were collected on admission. Univariate and bivariate analyzes were performed, using association measures (OR and Chi square), with their respective 95% confidence intervals (95% CI). Results: There was an initial population of 731 medical records of patients hospitalized for COVID-19. We worked with 300 medical records that met all the inclusion criteria, these were divided into two groups: deceased (n=114) and discharged (n=186). The average age of the total (n=300) was 55.9 (IQR: 18-91), with a predominance of males (60.7%). 77.7% of the entire population presented one or more comorbidities, among the most frequent: Arterial Hypertension (46%), Obesity (38.3%) and Diabetes Mellitus (35%). In the bivariate analysis, there was a significant association: Age ?60 with 58.8% (OR: 2.65; CI: 1.64-4.28); Prior Mediation 62.3% (OR: 3.64; CI: 2.23-5.94); ICU admission 53.5% (OR: 8.58; CI: 4.81-15.28); Oxygen supply 96.5% (OR: 9.03; CI: 3.15-25.86). 86.8% had one or more comorbidities (OR: 2.56; CI: 1.36-4.81); HT 62.3% (OR: 2.89; CI: 1.78-4.68) and ; DM2 44.7% (OR: 1.97; CI: 1.21-3.21); in laboratory tests on admission: PAFI <300 with 96.5% (OR: 12.77; CI: 4.49-36.30); SatO2 <93 with 97.4% (OR: 11.80; CI: 3.57-39.00); Glucose >130 with 53.5% (OR: 0.34; CI: 0.21-0.56) and LDH >720 with 72.8% (OR: 0.10; CI: 0.06-0.17 ). Conclusion: The risk factors with the greatest association with mortality from COVID-19 were: age ? 60 years, admission to the ICU, presenting ?1 comorbidity within the main ones: hypertension and DM2; PAFI <300, SATO2 <93, glucose ?130 and LDH ?720.