Atypical Alterations of cerebrospinal fluid in Guillain Barré Syndrome: Cases Reports.

• Autores: Zelada-Ríos, Laura, Guevara-Silva, Erik, Castro-Suarez, Sheila, Caparó-Zamalloa, César, Meza-Vega, María
• Formato: artículo
• Fecha de Publicación: 2021
• Institución: Universidad Peruana Cayetano Heredia
• Repositorio: Revistas - Universidad Peruana Cayetano Heredia
• Lenguaje: español
• OAI Identifier: oai:revistas.upch.edu.pe:article/3939
• Enlace del recurso: https://revistas.upch.edu.pe/index.php/RNP/article/view/3939
• Nivel de acceso: acceso abierto
• Materia: Disociación albuminocitológica; hipoglucorraquia; líquido cefalorraquídeo; pleocitosis; poliradiculopatía aguda axonal; Síndrome de Guillain-Barré

Guillain-Barré syndrome shows a cyto-albuminologic dissociation in most patients. Pleocytosis or hypoglycorrhachia may defer the diagnosis, a reason for which an infectious etiology must be ruled out. Three cases of Guillain- Barré are described, whose cerebrospinal fluid tests showed limphocytic pleocytosis and persistently elevated protein concentration, while one of the cases also showed hypoglycorrhachia, and the classic cyto-albuminologic dissociation was only demonstrated in subsequent analysis. The neurophysiologic evaluation revealed an axonal disruption in all the patients. The atypical alterations in the context of acute flaccid paralysis warrant a retesting of the cerebrospinal fluid in order to rule out other etiologies, but without postponing the start of treatment.