Comparison of the concentration of the transforming growth factor Beta 1 (TGF-β1) in synovial fluid of dogs with and without degenerative joint disease

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Degenerative joint disease (DJD) is a non-inflammatory pathology and characterized to be progressive, structural, and functional. The transforming growth factor Beta 1 (TGF-β1) is a regulatory cytokine participating in the production and deposition of extracellular matrix in various tissues, includi...

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Autores: Fischer Wiethuchter, Christof, Lepe, Valentina, Opazo, Álvaro, Luzio, Álvaro, Troncoso, Ignacio, Hernandez, Carolina
Formato: artículo
Fecha de Publicación:2018
Institución:Universidad Nacional Mayor de San Marcos
Repositorio:Revistas - Universidad Nacional Mayor de San Marcos
Lenguaje:español
OAI Identifier:oai:ojs.csi.unmsm:article/14758
Enlace del recurso:https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/14758
Nivel de acceso:acceso abierto
Materia:ttransforming growth factor β1
synovial fluid
canines
factor de crecimiento transformante β1
líquido sinovial
caninos
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spelling Comparison of the concentration of the transforming growth factor Beta 1 (TGF-β1) in synovial fluid of dogs with and without degenerative joint diseaseComparación de la concentración del factor de crecimiento transformante Beta 1 (TGF-β1) en líquido sinovial de perros con y sin enfermedad degenerativa articularFischer Wiethuchter, ChristofLepe, ValentinaOpazo, ÁlvaroLuzio, ÁlvaroTroncoso, IgnacioHernandez, Carolinattransforming growth factor β1synovial fluidcaninesfactor de crecimiento transformante β1líquido sinovialcaninosDegenerative joint disease (DJD) is a non-inflammatory pathology and characterized to be progressive, structural, and functional. The transforming growth factor Beta 1 (TGF-β1) is a regulatory cytokine participating in the production and deposition of extracellular matrix in various tissues, including joint cartilage. The aim of the present study was to compare the concentrations of transforming growth factor β1 in canine synovial fluid with (n=12) and without DJD (n=11), determined by an ELISA test. The mean concentration of TGB-β1 in dogs without DJD was 16.8 ± 7.1 ng/ml, while in dogs with DJD it was 10.3 ± 3.5 ng/ml (p <0.05).La enfermedad degenerativa articular (EDA) es una patología de carácter no inflamatorio en su origen, que se caracteriza en ser progresiva, estructural y funcional. El factor de crecimiento transformante Beta 1 (TGF-β1) es una citocina reguladora en la producción y depósito de matriz extracelular en varios tejidos, incluyendo el cartílago articular. El objetivo del presente estudio fue comparar las concentraciones del factor de crecimiento transformante β1 en líquido sinovial de caninos con (n=12) y sin EDA (n=11), determinado mediante una prueba de ELISA. La concentración media de TGB- β1 en perros sin EDA fue de 16.8 ± 7.1 ng/ml, mientras que en perros con EDA fue de 10.3 ± 3.5 ng/ml (p<0.05).Universidad Nacional Mayor de San Marcos, Facultad de Medicina Veterinaria2018-09-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdftext/htmlhttps://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/1475810.15381/rivep.v29i3.14758Revista de Investigaciones Veterinarias del Perú; Vol. 29 Núm. 3 (2018); 729-733Revista de Investigaciones Veterinarias del Perú; Vol. 29 No. 3 (2018); 729-7331682-34191609-9117reponame:Revistas - Universidad Nacional Mayor de San Marcosinstname:Universidad Nacional Mayor de San Marcosinstacron:UNMSMspahttps://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/14758/13069https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/14758/13880Derechos de autor 2018 Christof Fischer Wiethuchter, Valentina Lepe, Álvaro Opazo, Álvaro Luzio, Ignacio Troncoso, Carolina Hernandezhttps://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccessoai:ojs.csi.unmsm:article/147582018-12-21T09:58:01Z
dc.title.none.fl_str_mv Comparison of the concentration of the transforming growth factor Beta 1 (TGF-β1) in synovial fluid of dogs with and without degenerative joint disease
Comparación de la concentración del factor de crecimiento transformante Beta 1 (TGF-β1) en líquido sinovial de perros con y sin enfermedad degenerativa articular
title Comparison of the concentration of the transforming growth factor Beta 1 (TGF-β1) in synovial fluid of dogs with and without degenerative joint disease
spellingShingle Comparison of the concentration of the transforming growth factor Beta 1 (TGF-β1) in synovial fluid of dogs with and without degenerative joint disease
Fischer Wiethuchter, Christof
ttransforming growth factor β1
synovial fluid
canines
factor de crecimiento transformante β1
líquido sinovial
caninos
title_short Comparison of the concentration of the transforming growth factor Beta 1 (TGF-β1) in synovial fluid of dogs with and without degenerative joint disease
title_full Comparison of the concentration of the transforming growth factor Beta 1 (TGF-β1) in synovial fluid of dogs with and without degenerative joint disease
title_fullStr Comparison of the concentration of the transforming growth factor Beta 1 (TGF-β1) in synovial fluid of dogs with and without degenerative joint disease
title_full_unstemmed Comparison of the concentration of the transforming growth factor Beta 1 (TGF-β1) in synovial fluid of dogs with and without degenerative joint disease
title_sort Comparison of the concentration of the transforming growth factor Beta 1 (TGF-β1) in synovial fluid of dogs with and without degenerative joint disease
dc.creator.none.fl_str_mv Fischer Wiethuchter, Christof
Lepe, Valentina
Opazo, Álvaro
Luzio, Álvaro
Troncoso, Ignacio
Hernandez, Carolina
author Fischer Wiethuchter, Christof
author_facet Fischer Wiethuchter, Christof
Lepe, Valentina
Opazo, Álvaro
Luzio, Álvaro
Troncoso, Ignacio
Hernandez, Carolina
author_role author
author2 Lepe, Valentina
Opazo, Álvaro
Luzio, Álvaro
Troncoso, Ignacio
Hernandez, Carolina
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv ttransforming growth factor β1
synovial fluid
canines
factor de crecimiento transformante β1
líquido sinovial
caninos
topic ttransforming growth factor β1
synovial fluid
canines
factor de crecimiento transformante β1
líquido sinovial
caninos
description Degenerative joint disease (DJD) is a non-inflammatory pathology and characterized to be progressive, structural, and functional. The transforming growth factor Beta 1 (TGF-β1) is a regulatory cytokine participating in the production and deposition of extracellular matrix in various tissues, including joint cartilage. The aim of the present study was to compare the concentrations of transforming growth factor β1 in canine synovial fluid with (n=12) and without DJD (n=11), determined by an ELISA test. The mean concentration of TGB-β1 in dogs without DJD was 16.8 ± 7.1 ng/ml, while in dogs with DJD it was 10.3 ± 3.5 ng/ml (p <0.05).
publishDate 2018
dc.date.none.fl_str_mv 2018-09-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/14758
10.15381/rivep.v29i3.14758
url https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/14758
identifier_str_mv 10.15381/rivep.v29i3.14758
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/14758/13069
https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/14758/13880
dc.rights.none.fl_str_mv https://creativecommons.org/licenses/by-nc-sa/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
text/html
dc.publisher.none.fl_str_mv Universidad Nacional Mayor de San Marcos, Facultad de Medicina Veterinaria
publisher.none.fl_str_mv Universidad Nacional Mayor de San Marcos, Facultad de Medicina Veterinaria
dc.source.none.fl_str_mv Revista de Investigaciones Veterinarias del Perú; Vol. 29 Núm. 3 (2018); 729-733
Revista de Investigaciones Veterinarias del Perú; Vol. 29 No. 3 (2018); 729-733
1682-3419
1609-9117
reponame:Revistas - Universidad Nacional Mayor de San Marcos
instname:Universidad Nacional Mayor de San Marcos
instacron:UNMSM
instname_str Universidad Nacional Mayor de San Marcos
instacron_str UNMSM
institution UNMSM
reponame_str Revistas - Universidad Nacional Mayor de San Marcos
collection Revistas - Universidad Nacional Mayor de San Marcos
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 13.905277
Comparison of the concentration of the transforming growth factor Beta 1 (TGF-β1) in synovial fluid of dogs with and without degenerative joint disease
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