Ethanolic flower extract from Laccopetalum giganteum (pacra-pacra) increases fertility in rats
Descripción del Articulo
Objective: To determine whether oral administration of the ethanolic flower extract from Laccopetalum giganteum (pacra-pacra) increases fertility in normal rats. Design: Experimental study. Setting: Faculty of Medicine and Faculty of Pharmacy and Biochemistry, Universidad Nacional Mayor de San Marco...
| Autores: | , , , , , , |
|---|---|
| Formato: | artículo |
| Fecha de Publicación: | 2007 |
| Institución: | Universidad Nacional Mayor de San Marcos |
| Repositorio: | Revistas - Universidad Nacional Mayor de San Marcos |
| Lenguaje: | español |
| OAI Identifier: | oai:ojs.csi.unmsm:article/1209 |
| Enlace del recurso: | https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/1209 |
| Nivel de acceso: | acceso abierto |
| Materia: | Extractos vegetales fertilidad investigación Plant extracts fertility research |
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REVUNMSM |
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Revistas - Universidad Nacional Mayor de San Marcos |
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Ethanolic flower extract from Laccopetalum giganteum (pacra-pacra) increases fertility in rats El extracto etanólico de las flores de Laccopetalum giganteum (pacra-pacra) aumenta la fertilidad en ratas |
| title |
Ethanolic flower extract from Laccopetalum giganteum (pacra-pacra) increases fertility in rats |
| spellingShingle |
Ethanolic flower extract from Laccopetalum giganteum (pacra-pacra) increases fertility in rats Arroyo, Jorge Extractos vegetales fertilidad investigación Plant extracts fertility research |
| title_short |
Ethanolic flower extract from Laccopetalum giganteum (pacra-pacra) increases fertility in rats |
| title_full |
Ethanolic flower extract from Laccopetalum giganteum (pacra-pacra) increases fertility in rats |
| title_fullStr |
Ethanolic flower extract from Laccopetalum giganteum (pacra-pacra) increases fertility in rats |
| title_full_unstemmed |
Ethanolic flower extract from Laccopetalum giganteum (pacra-pacra) increases fertility in rats |
| title_sort |
Ethanolic flower extract from Laccopetalum giganteum (pacra-pacra) increases fertility in rats |
| dc.creator.none.fl_str_mv |
Arroyo, Jorge Barreda, Alejandro Ráez, Ernesto Jurado, Bertha Moral, Gloria Martínez, Jaime Palomino, Christian |
| author |
Arroyo, Jorge |
| author_facet |
Arroyo, Jorge Barreda, Alejandro Ráez, Ernesto Jurado, Bertha Moral, Gloria Martínez, Jaime Palomino, Christian |
| author_role |
author |
| author2 |
Barreda, Alejandro Ráez, Ernesto Jurado, Bertha Moral, Gloria Martínez, Jaime Palomino, Christian |
| author2_role |
author author author author author author |
| dc.subject.none.fl_str_mv |
Extractos vegetales fertilidad investigación Plant extracts fertility research |
| topic |
Extractos vegetales fertilidad investigación Plant extracts fertility research |
| description |
Objective: To determine whether oral administration of the ethanolic flower extract from Laccopetalum giganteum (pacra-pacra) increases fertility in normal rats. Design: Experimental study. Setting: Faculty of Medicine and Faculty of Pharmacy and Biochemistry, Universidad Nacional Mayor de San Marcos. Biologic material: Rats. Interventions: Forty-eight rats were randomly distributed into 2 groups of 24 rats each. The first control group received solución salina fisiológica (SSF) 5 mL/kg and the second group 300 mg/kg of the extract, orally, for 15 days. Each group had 6 female rats and 6 male rats living together and 6 female rats and 6 male rats lived separate. The animals living together were sacrificed in order to observe the fetuses in the uterus. The animals that lived separate had blood samples taken in order to determine testosterone levels in male rats and LH, FSH, estrogen and progesterone levels in female rats using electro chemiluminescence. At the same time, liver function tests, urea and creatinine tests were done. Main outcome measures: Pregnancy, FSH, LH, estrogens and progesterone in female rats; testosterone in male rats. Results: Flavonoids, tannins and phenolic compounds were found in higher quantities in the ethanolic extract. All female rats receiving the plant extract and living together with the male rats got pregnant and the ones that lived separate had increased levels of FSH. Male rats had increased levels of testosterone as compared to the control group. Liver function tests, urea and creatinine were within acceptable limits. Conclusions: The ethanolic flower extract from Laccopetalum giganteum (pacra-pacra) increased fertility in normal rats. |
| publishDate |
2007 |
| dc.date.none.fl_str_mv |
2007-09-17 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.none.fl_str_mv |
https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/1209 10.15381/anales.v68i3.1209 |
| url |
https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/1209 |
| identifier_str_mv |
10.15381/anales.v68i3.1209 |
| dc.language.none.fl_str_mv |
spa |
| language |
spa |
| dc.relation.none.fl_str_mv |
https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/1209/1015 |
| dc.rights.none.fl_str_mv |
https://creativecommons.org/licenses/by-nc-sa/4.0 info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by-nc-sa/4.0 |
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openAccess |
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application/pdf |
| dc.publisher.none.fl_str_mv |
Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana |
| publisher.none.fl_str_mv |
Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana |
| dc.source.none.fl_str_mv |
Anales de la Facultad de Medicina; Vol. 68 No. 3 (2007); 238-243 Anales de la Facultad de Medicina; Vol. 68 Núm. 3 (2007); 238-243 1609-9419 1025-5583 reponame:Revistas - Universidad Nacional Mayor de San Marcos instname:Universidad Nacional Mayor de San Marcos instacron:UNMSM |
| instname_str |
Universidad Nacional Mayor de San Marcos |
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UNMSM |
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UNMSM |
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Revistas - Universidad Nacional Mayor de San Marcos |
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Revistas - Universidad Nacional Mayor de San Marcos |
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1795238242013937664 |
| spelling |
Ethanolic flower extract from Laccopetalum giganteum (pacra-pacra) increases fertility in ratsEl extracto etanólico de las flores de Laccopetalum giganteum (pacra-pacra) aumenta la fertilidad en ratasArroyo, JorgeBarreda, AlejandroRáez, ErnestoJurado, BerthaMoral, GloriaMartínez, JaimePalomino, ChristianExtractos vegetalesfertilidadinvestigaciónPlant extractsfertilityresearchObjective: To determine whether oral administration of the ethanolic flower extract from Laccopetalum giganteum (pacra-pacra) increases fertility in normal rats. Design: Experimental study. Setting: Faculty of Medicine and Faculty of Pharmacy and Biochemistry, Universidad Nacional Mayor de San Marcos. Biologic material: Rats. Interventions: Forty-eight rats were randomly distributed into 2 groups of 24 rats each. The first control group received solución salina fisiológica (SSF) 5 mL/kg and the second group 300 mg/kg of the extract, orally, for 15 days. Each group had 6 female rats and 6 male rats living together and 6 female rats and 6 male rats lived separate. The animals living together were sacrificed in order to observe the fetuses in the uterus. The animals that lived separate had blood samples taken in order to determine testosterone levels in male rats and LH, FSH, estrogen and progesterone levels in female rats using electro chemiluminescence. At the same time, liver function tests, urea and creatinine tests were done. Main outcome measures: Pregnancy, FSH, LH, estrogens and progesterone in female rats; testosterone in male rats. Results: Flavonoids, tannins and phenolic compounds were found in higher quantities in the ethanolic extract. All female rats receiving the plant extract and living together with the male rats got pregnant and the ones that lived separate had increased levels of FSH. Male rats had increased levels of testosterone as compared to the control group. Liver function tests, urea and creatinine were within acceptable limits. Conclusions: The ethanolic flower extract from Laccopetalum giganteum (pacra-pacra) increased fertility in normal rats.Objetivos: Determinar si la administración por vía oral del extracto etanólico de flores de Laccopetalum giganteum (Pacra-pacra) en ratas normales aumenta la fertilidad. Diseño: Estudio experimental. Lugar: Facultad de Medicina y Facultad de Farmacia y Bioquímica, Universidad Nacional Mayor de San Marcos. Material biológico: Ratas. Intervenciones: Cuarentiocho animales fueron divididos aleatoriamente en 2 grandes grupos, de 24 cada uno. El primero fue control, con solución salina fisiológica (SSF) 5mL/kg y el segundo con extracto vía oral, 300 mg/kg, durante 15 días. Cada grupo consideró 6 hembras y 6 machos juntos, y 6 hembras y 6 machos separados. Los animales que estuvieron juntos fueron sacrificados, para observar la presencia de fetos en el útero; y a los animales que estuvieron separados, se les extrajo muestra de sangre, para conocer el nivel de testosterona en machos y LH, FSH, estrógenos y progesterona en hembras, expresándose en ug/dL; el dosaje hormonal se realizó por el método de electroquimioluminiscencia. Asimismo, se determinó GOT, GPT, urea y creatinina, según las técnicas utilizadas en el laboratorio clínico. Principales medidas de resultados: Gravidez, FSH, LH, estrógenos y progesterona en ratas hembras; testosterona en ratas machos. Resultados: Los flavonoides, compuestos fenólicos y taninos estuvieron en mayor cantidad en el extracto etanólico. El 100% de ratas que recibió el extracto etanólico de la planta y estuvo junto a los machos resultó grávida; y, las separadas que recibieron el mismo extracto, presentaron incremento de FSH en las hembras y testosterona en los machos, comparativamente a los controles respectivos. Los niveles de GOT, GPT, urea y creatinina se encontraron dentro de los límites aceptados. Conclusiones: En condiciones experimentales, el extracto etanólico de las flores de Laccopetalum giganteum (pacra-pacra) incrementó la fertilidad en ratas normales.Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana2007-09-17info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/120910.15381/anales.v68i3.1209Anales de la Facultad de Medicina; Vol. 68 No. 3 (2007); 238-243Anales de la Facultad de Medicina; Vol. 68 Núm. 3 (2007); 238-2431609-94191025-5583reponame:Revistas - Universidad Nacional Mayor de San Marcosinstname:Universidad Nacional Mayor de San Marcosinstacron:UNMSMspahttps://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/1209/1015Derechos de autor 2007 Jorge Arroyo, Alejandro Barreda, Ernesto Ráez, Bertha Jurado, Gloria Moral, Jaime Martínez, Christian Palominohttps://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccessoai:ojs.csi.unmsm:article/12092020-04-14T21:48:09Z |
| score |
13.905282 |
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La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).
