Antifungal effect in vitro of Origanum Vulgare in Candida Albicans strains

• Autores: Villavicencio Gastelú, Jorge Eleodoro, Moromi Nakata, Hilda, Salcedo- Moncada, Doris, Pineda-Mejía, Martha, Ramos Perfecto, Donald, Zambrano de la Peña, Livia Sonia, Martínez Cadillo, Elba Estefanía, Mendoza Rojas, Gilberto Alejandro, Petkova-Gueorguieva, Marieta, Bardales Álvarez, Roxana Margarita
• Formato: artículo
• Fecha de Publicación: 2016
• Institución: Universidad Nacional Mayor de San Marcos
• Repositorio: Revistas - Universidad Nacional Mayor de San Marcos
• Lenguaje: español
• OAI Identifier: oai:ojs.csi.unmsm:article/12907
• Enlace del recurso: https://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/12907
• Nivel de acceso: acceso abierto
• Materia: Origanum vulgare; Candida albicans; antimicótico; Antifungal Agents.

Objective: To evaluate the in vitro antimycotic effect of Origanum vulgare essential oil on Candida albi-cans strain ATCC 10231 Material and method: Selection of four different oregano geotypes was carried out, the essential oils were obtained by distillation by Drag with steam; Its quantitative chemical com-position was determined by Gas Chromatography, Mass Spectrometry (GC / MS). The antimicrotic activity of essential oils was evaluated in vitro through sensitivity tests with the disk diffusion method in agar culture against C. albicans. Results: The results showed high antimycotic activity of all oils from the concentration of 12.5%. Conclusions: Essential oils of Origanum vulgare from different geotypes show differences in their antifungal effects. The essential oil of Origanum vulgare may be is a pharmacological alternative for the treatment of fungal infections in the mouth.