Meningoencephalitis caused by Mycobacterium bovis in a calf. Case report

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A clinical case of tuberculous meningoencephalitis in a 5-month-old Holstein calf that presented nervous symptoms is described. The calf was part of a herd with a 30% prevalence of tuberculosis. The animal was euthanized, and a necropsy was performed. No lesions were found in organs of the thoracic...

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Detalles Bibliográficos
Autores: Favila-Humara, Lucia del Carmen, Santillán-Flores, Marco Antonio, Martínez-Serrano, María Guadalupe, Morales-Álvarez, José Francisco
Formato: artículo
Fecha de Publicación:2021
Institución:Universidad Nacional Mayor de San Marcos
Repositorio:Revistas - Universidad Nacional Mayor de San Marcos
Lenguaje:español
OAI Identifier:oai:ojs.csi.unmsm:article/19498
Enlace del recurso:https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/19498
Nivel de acceso:acceso abierto
Materia:bovine tuberculosis
meningoencephalitis
Mycobacterium bovis
PCR
tuberculosis bovina
meningoencefalitis
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spelling Meningoencephalitis caused by Mycobacterium bovis in a calf. Case reportMeningoencefalitis causada por Mycobacterium bovis en un ternero. Reporte de casoFavila-Humara, Lucia del CarmenSantillán-Flores, Marco AntonioMartínez-Serrano, María GuadalupeMorales-Álvarez, José Franciscobovine tuberculosismeningoencephalitisMycobacterium bovisPCRtuberculosis bovinameningoencefalitisMycobacterium bovisPCRA clinical case of tuberculous meningoencephalitis in a 5-month-old Holstein calf that presented nervous symptoms is described. The calf was part of a herd with a 30% prevalence of tuberculosis. The animal was euthanized, and a necropsy was performed. No lesions were found in organs of the thoracic or abdominal cavity. Brain samples were taken for histopathology (hematoxylin-eosin and Zielh Nelsen staining), bacteriology and PCR-MRD1 studies. In the brain, macroscopic inflammatory lesions with congestion and granular appearance were observed in the meninges, as well as fibrous adhesions in the ventral area. Microscopically, inflammatory infiltrate, lymphocytes, macrophages, epithelioid cells, plasma cells and multinucleated giant cells, areas of central necrosis, dystrophic mineralization and acid-fast bacilli were observed. Granulomatous meningoencephalitis due to Mycobacterium bovis was confirmed by bacterial isolation and PCR-MRD1.Se describe un caso clínico de meningoencefalitis tuberculosa en un ternero Holstein de cinco meses de edad que presentaba signología nerviosa; además de pertenecer a un hato con 30% de prevalencia a tuberculosis. Se llevó a cabo la eutanasia del animal y se practicó la necropsia. No se encontraron lesiones en órganos de cavidad torácica ni abdominal. Se tomaron muestras de encéfalo para estudios de histopatología (tinción con hematoxilina-eosina y Zielh Nelsen), bacteriología y PCR-MRD1. En el encéfalo se observaron lesiones inflamatorias macroscópicas con congestión y aspecto granular en meninges, así como adherencias fibrosas en la zona ventral. Microscópicamente se observó infiltrado inflamatorio, linfocitos, macrófagos, células epitelioides, células plasmáticas y células gigantes multinucleadas, áreas de necrosis central, mineralización distrófica y bacilos ácido-alcohol resistentes. La meningoencefalitis granulomatosa por Mycobacterium bovis se confirmó por aislamiento bacteriano y PCR-MRD1.Universidad Nacional Mayor de San Marcos, Facultad de Medicina Veterinaria2021-02-26info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/1949810.15381/rivep.v32i1.19498Revista de Investigaciones Veterinarias del Perú; Vol. 32 Núm. 1 (2021); e19498Revista de Investigaciones Veterinarias del Perú; Vol. 32 No. 1 (2021); e194981682-34191609-9117reponame:Revistas - Universidad Nacional Mayor de San Marcosinstname:Universidad Nacional Mayor de San Marcosinstacron:UNMSMspahttps://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/19498/16408Derechos de autor 2021 Lucia del Carmen Favila-Humara, Marco Antonio Santillán-Flores, María Guadalupe Martínez-Serrano, José Francisco Morales-Álvarezhttps://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccessoai:ojs.csi.unmsm:article/194982021-02-26T18:53:16Z
dc.title.none.fl_str_mv Meningoencephalitis caused by Mycobacterium bovis in a calf. Case report
Meningoencefalitis causada por Mycobacterium bovis en un ternero. Reporte de caso
title Meningoencephalitis caused by Mycobacterium bovis in a calf. Case report
spellingShingle Meningoencephalitis caused by Mycobacterium bovis in a calf. Case report
Favila-Humara, Lucia del Carmen
bovine tuberculosis
meningoencephalitis
Mycobacterium bovis
PCR
tuberculosis bovina
meningoencefalitis
Mycobacterium bovis
PCR
title_short Meningoencephalitis caused by Mycobacterium bovis in a calf. Case report
title_full Meningoencephalitis caused by Mycobacterium bovis in a calf. Case report
title_fullStr Meningoencephalitis caused by Mycobacterium bovis in a calf. Case report
title_full_unstemmed Meningoencephalitis caused by Mycobacterium bovis in a calf. Case report
title_sort Meningoencephalitis caused by Mycobacterium bovis in a calf. Case report
dc.creator.none.fl_str_mv Favila-Humara, Lucia del Carmen
Santillán-Flores, Marco Antonio
Martínez-Serrano, María Guadalupe
Morales-Álvarez, José Francisco
author Favila-Humara, Lucia del Carmen
author_facet Favila-Humara, Lucia del Carmen
Santillán-Flores, Marco Antonio
Martínez-Serrano, María Guadalupe
Morales-Álvarez, José Francisco
author_role author
author2 Santillán-Flores, Marco Antonio
Martínez-Serrano, María Guadalupe
Morales-Álvarez, José Francisco
author2_role author
author
author
dc.subject.none.fl_str_mv bovine tuberculosis
meningoencephalitis
Mycobacterium bovis
PCR
tuberculosis bovina
meningoencefalitis
Mycobacterium bovis
PCR
topic bovine tuberculosis
meningoencephalitis
Mycobacterium bovis
PCR
tuberculosis bovina
meningoencefalitis
Mycobacterium bovis
PCR
description A clinical case of tuberculous meningoencephalitis in a 5-month-old Holstein calf that presented nervous symptoms is described. The calf was part of a herd with a 30% prevalence of tuberculosis. The animal was euthanized, and a necropsy was performed. No lesions were found in organs of the thoracic or abdominal cavity. Brain samples were taken for histopathology (hematoxylin-eosin and Zielh Nelsen staining), bacteriology and PCR-MRD1 studies. In the brain, macroscopic inflammatory lesions with congestion and granular appearance were observed in the meninges, as well as fibrous adhesions in the ventral area. Microscopically, inflammatory infiltrate, lymphocytes, macrophages, epithelioid cells, plasma cells and multinucleated giant cells, areas of central necrosis, dystrophic mineralization and acid-fast bacilli were observed. Granulomatous meningoencephalitis due to Mycobacterium bovis was confirmed by bacterial isolation and PCR-MRD1.
publishDate 2021
dc.date.none.fl_str_mv 2021-02-26
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/19498
10.15381/rivep.v32i1.19498
url https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/19498
identifier_str_mv 10.15381/rivep.v32i1.19498
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/19498/16408
dc.rights.none.fl_str_mv https://creativecommons.org/licenses/by-nc-sa/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidad Nacional Mayor de San Marcos, Facultad de Medicina Veterinaria
publisher.none.fl_str_mv Universidad Nacional Mayor de San Marcos, Facultad de Medicina Veterinaria
dc.source.none.fl_str_mv Revista de Investigaciones Veterinarias del Perú; Vol. 32 Núm. 1 (2021); e19498
Revista de Investigaciones Veterinarias del Perú; Vol. 32 No. 1 (2021); e19498
1682-3419
1609-9117
reponame:Revistas - Universidad Nacional Mayor de San Marcos
instname:Universidad Nacional Mayor de San Marcos
instacron:UNMSM
instname_str Universidad Nacional Mayor de San Marcos
instacron_str UNMSM
institution UNMSM
reponame_str Revistas - Universidad Nacional Mayor de San Marcos
collection Revistas - Universidad Nacional Mayor de San Marcos
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 13.92687
Meningoencephalitis caused by Mycobacterium bovis in a calf. Case report
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