Therapeutic adherence to Helicobacter pylori eradication treatment and its associated factors in a public hospital in Peru

• Autores: Vargas Cárdenas, Gloria, Balvin Yanes, Lucía, Chaiña Meza, Jimena Marisol, Llanos Tejada, Félix
• Formato: artículo
• Fecha de Publicación: 2020
• Institución: Sociedad de Gastroenterología del Perú
• Repositorio: Revista de Gastroenterología del Perú
• Lenguaje: español
• OAI Identifier: oai:ojs.revistagastroperu.com:article/1121
• Enlace del recurso: http://www.revistagastroperu.com/index.php/rgp/article/view/1121
• Nivel de acceso: acceso abierto
• Materia: Cumplimiento y adherencia al tratamiento; Factores de riesgo; Helicobacter pylori

Objective: To determine the factors associated with adherence to Helicobacter pylori eradication treatment in patients with theinfection. Materials and methods: A longitudinal prospective cohort analytical observational study was conducted, including 100 patients who initiated Helicobacter pylori eradication treatment. The Morisky Green test was applied to measure adherence to treatment and the Battle Test was applied to measure knowledge about Helicobacter pylori infection. The Chi-square test was performed to determine the association of factors with adherence to treatment and logistic regression analysis to estimate crude RR and adjusted RR. Results: Of the 100 patients, 64% were found to be female. The average age was 49.9 years and 65%were adherent to treatment. Factors associated with lack of treatment adherence were: age under 50 years (adjusted RR 3.95, 95% CI: 1.09-14.33), lack of higher studies (adjusted RR: 5.1, 95% CI: 1.26-20.5) and presence of adverse reactions (adjusted RR: 5.88, 95% CI: 1.56-22.2). Conclusions: Most patients were found to be adherent to the treatment. The risk factors for poor adherence were adverse reactions, age under 50 years and lack of higher education.