How Can Genomic Innovations in Pediatric Brain Tumors Transform Outcomes in Low- and Middle-Income Countries?

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Advances in molecular diagnostics have led to improved stratification and targeted interventions in the treatment of children with brain tumors. This has necessitated complex infrastructure to deliver all the required testing in a clinically useful time period. However, in less-resourced countries,...

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Detalles Bibliográficos
Autores: Bailey, S, Davidson, AA, Parkes, J, Tabori, U, Figaji, A, Epari, S, Chinnaswamy, G, Dias-Coronado, R, Casavilca-Zambrano, S, Amayiri, N, Vassal, G, Bouffet, E, Clifford, SC
Formato: revisión
Fecha de Publicación:2022
Institución:Instituto Nacional de Enfermedades Neoplásicas
Repositorio:INEN-Institucional
Lenguaje:inglés
OAI Identifier:oai:repositorio.inen.sld.pe:20.500.14703/324
Enlace del recurso:https: //doi.org/10.1200/GO.22.00156
https://hdl.handle.net/20.500.14703/324
Nivel de acceso:acceso abierto
Materia:Brain Neoplasms
Child
Developing Countries
Genomics
Humans
Income
https://purl.org/pe-repo/ocde/ford#3.02.21
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spelling PublicationBailey, SDavidson, AAParkes, JTabori, UFigaji, AEpari, SChinnaswamy, GDias-Coronado, RCasavilca-Zambrano, SAmayiri, NVassal, GBouffet, EClifford, SC2025-01-02T14:42:38Z2025-01-02T14:42:38Z2022https: //doi.org/10.1200/GO.22.00156https://hdl.handle.net/20.500.14703/324JCO global oncologyAdvances in molecular diagnostics have led to improved stratification and targeted interventions in the treatment of children with brain tumors. This has necessitated complex infrastructure to deliver all the required testing in a clinically useful time period. However, in less-resourced countries, this testing is not routinely available and an ever-widening gap in the ability to deliver more tailored therapies including targeted agents is increasingly evident. This article reviews the recent advances and suggests practical ways of ensuring that genomic advances are applied according to available resources.application/pdfengLippincott Williams and WilkinsUSinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/4.0/Brain NeoplasmsChildDeveloping CountriesGenomicsHumansIncomehttps://purl.org/pe-repo/ocde/ford#3.02.21How Can Genomic Innovations in Pediatric Brain Tumors Transform Outcomes in Low- and Middle-Income Countries?info:eu-repo/semantics/reviewinfo:eu-repo/semantics/publishedVersionreponame:INEN-Institucionalinstname:Instituto Nacional de Enfermedades Neoplásicasinstacron:INENORIGINALgo-8-e2200156.pdfapplication/pdf300788https://repositorio.inen.sld.pe/backend/api/core/bitstreams/4b1b51d5-01ed-445f-8422-285763033867/downloada1e93ed55c0b8858b93686aae0c3c11aMD51trueAnonymousREADTEXTgo-8-e2200156.pdf.txtWritten by FormatFilter org.dspace.app.mediafilter.TikaTextExtractionFilter on 2025-08-22T08:05:26Z (GMT).Extracted texttext/plain65047https://repositorio.inen.sld.pe/backend/api/core/bitstreams/b7a4b4a0-1f47-4cdb-9ea4-4a34fa809dc3/download35161e79253a1e4a967e9cbbb2e6bf1eMD52falseAnonymousREADTHUMBNAILgo-8-e2200156.pdf.jpgWritten by FormatFilter org.dspace.app.mediafilter.PDFBoxThumbnail on 2025-08-22T08:05:26Z (GMT).Generated Thumbnailimage/jpeg49150https://repositorio.inen.sld.pe/backend/api/core/bitstreams/58b1f441-bba3-4bdc-a2ec-1dd7b1a320a4/downloade2aaefc1dff931ad4608a7e671cfb921MD53falseAnonymousREAD20.500.14703/324oai:repositorio.inen.sld.pe:20.500.14703/3242026-02-15T18:16:30.271Zhttps://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessopen.accesshttps://repositorio.inen.sld.peRepositorio del Instituto Nacional de Enfermedades Neoplásicasrepositorio@inen.sld.pe
dc.title.none.fl_str_mv How Can Genomic Innovations in Pediatric Brain Tumors Transform Outcomes in Low- and Middle-Income Countries?
title How Can Genomic Innovations in Pediatric Brain Tumors Transform Outcomes in Low- and Middle-Income Countries?
spellingShingle How Can Genomic Innovations in Pediatric Brain Tumors Transform Outcomes in Low- and Middle-Income Countries?
Bailey, S
Brain Neoplasms
Child
Developing Countries
Genomics
Humans
Income
https://purl.org/pe-repo/ocde/ford#3.02.21
title_short How Can Genomic Innovations in Pediatric Brain Tumors Transform Outcomes in Low- and Middle-Income Countries?
title_full How Can Genomic Innovations in Pediatric Brain Tumors Transform Outcomes in Low- and Middle-Income Countries?
title_fullStr How Can Genomic Innovations in Pediatric Brain Tumors Transform Outcomes in Low- and Middle-Income Countries?
title_full_unstemmed How Can Genomic Innovations in Pediatric Brain Tumors Transform Outcomes in Low- and Middle-Income Countries?
title_sort How Can Genomic Innovations in Pediatric Brain Tumors Transform Outcomes in Low- and Middle-Income Countries?
author Bailey, S
author_facet Bailey, S
Davidson, AA
Parkes, J
Tabori, U
Figaji, A
Epari, S
Chinnaswamy, G
Dias-Coronado, R
Casavilca-Zambrano, S
Amayiri, N
Vassal, G
Bouffet, E
Clifford, SC
author_role author
author2 Davidson, AA
Parkes, J
Tabori, U
Figaji, A
Epari, S
Chinnaswamy, G
Dias-Coronado, R
Casavilca-Zambrano, S
Amayiri, N
Vassal, G
Bouffet, E
Clifford, SC
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Bailey, S
Davidson, AA
Parkes, J
Tabori, U
Figaji, A
Epari, S
Chinnaswamy, G
Dias-Coronado, R
Casavilca-Zambrano, S
Amayiri, N
Vassal, G
Bouffet, E
Clifford, SC
dc.subject.none.fl_str_mv Brain Neoplasms
Child
Developing Countries
Genomics
Humans
Income
topic Brain Neoplasms
Child
Developing Countries
Genomics
Humans
Income
https://purl.org/pe-repo/ocde/ford#3.02.21
dc.subject.ocde.none.fl_str_mv https://purl.org/pe-repo/ocde/ford#3.02.21
description Advances in molecular diagnostics have led to improved stratification and targeted interventions in the treatment of children with brain tumors. This has necessitated complex infrastructure to deliver all the required testing in a clinically useful time period. However, in less-resourced countries, this testing is not routinely available and an ever-widening gap in the ability to deliver more tailored therapies including targeted agents is increasingly evident. This article reviews the recent advances and suggests practical ways of ensuring that genomic advances are applied according to available resources.
publishDate 2022
dc.date.accessioned.none.fl_str_mv 2025-01-02T14:42:38Z
dc.date.available.none.fl_str_mv 2025-01-02T14:42:38Z
dc.date.issued.fl_str_mv 2022
dc.type.none.fl_str_mv info:eu-repo/semantics/review
dc.type.version.none.fl_str_mv info:eu-repo/semantics/publishedVersion
format review
status_str publishedVersion
dc.identifier.doi.none.fl_str_mv https: //doi.org/10.1200/GO.22.00156
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.14703/324
dc.identifier.journal.none.fl_str_mv JCO global oncology
url https: //doi.org/10.1200/GO.22.00156
https://hdl.handle.net/20.500.14703/324
identifier_str_mv JCO global oncology
dc.language.iso.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.uri.none.fl_str_mv https://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0/
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Lippincott Williams and Wilkins
dc.publisher.country.none.fl_str_mv US
publisher.none.fl_str_mv Lippincott Williams and Wilkins
dc.source.none.fl_str_mv reponame:INEN-Institucional
instname:Instituto Nacional de Enfermedades Neoplásicas
instacron:INEN
instname_str Instituto Nacional de Enfermedades Neoplásicas
instacron_str INEN
institution INEN
reponame_str INEN-Institucional
collection INEN-Institucional
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How Can Genomic Innovations in Pediatric Brain Tumors Transform Outcomes in Low- and Middle-Income Countries?
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