Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations
Descripción del Articulo
Se realizó un análisis exhaustivo, utilizando un mapeo fino denso, para identificar variantes robustas e independientes que predisponen el Lupus Eritematoso Sistémico (LES), para predecir y validar los efectos moleculares de los alelos de riesgo de LES a través de la bioinformática, modelización mol...
| Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | artículo |
| Fecha de Publicación: | 2014 |
| Institución: | Seguro Social de Salud |
| Repositorio: | ESSALUD-Institucional |
| Lenguaje: | inglés |
| OAI Identifier: | oai:repositorio.essalud.gob.pe:20.500.12959/490 |
| Enlace del recurso: | https://hdl.handle.net/20.500.12959/490 |
| Nivel de acceso: | acceso abierto |
| Materia: | Reumatología Lupus Eritematoso Sistémico Genética Humana https://purl.org/pe-repo/ocde/ford#3.05.00 |
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| dc.title.es_PE.fl_str_mv |
Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations |
| title |
Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations |
| spellingShingle |
Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations Kim-Howard, Xana Reumatología Lupus Eritematoso Sistémico Genética Humana https://purl.org/pe-repo/ocde/ford#3.05.00 |
| title_short |
Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations |
| title_full |
Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations |
| title_fullStr |
Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations |
| title_full_unstemmed |
Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations |
| title_sort |
Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations |
| author |
Kim-Howard, Xana |
| author_facet |
Kim-Howard, Xana Sun, Celi Molineros, Julio E. Maiti, Amit K. Chandru, Hema Adler, Adam Wiley, Graham B. Kaufman, Kenneth M. Kottyan, Leah Guthridge, Joel M. Rasmussen, Astrid Kelly, Jennifer Sánchez, Elena Raj, Prithvi Li, Quan-Zhen Bang, So-Young Lee, Hye-Soon Kim, Tae-Hwan Kang, Young Mo Suh, Chang-Hee Chung, Won Tae Park, Yong-Beom Choe, Jung-Yoon Shim, Seung Cheol Lee, Shin-Seok Han, Bok-Ghee Olsen, Nancy J. Karp, David R. Moser, Kathy Pons-Estel, Bernardo A. Wakeland, Edward K. James, Judith A. Harley, John B. Bae, Sang-Cheol Gaffney, Patrick M. Alarcón-Riquelme, Marta Looger, Loren L. Nath, Swapan K. Acevedo-Vasquez, Eduardo GENLES Network Group |
| author_role |
author |
| author2 |
Sun, Celi Molineros, Julio E. Maiti, Amit K. Chandru, Hema Adler, Adam Wiley, Graham B. Kaufman, Kenneth M. Kottyan, Leah Guthridge, Joel M. Rasmussen, Astrid Kelly, Jennifer Sánchez, Elena Raj, Prithvi Li, Quan-Zhen Bang, So-Young Lee, Hye-Soon Kim, Tae-Hwan Kang, Young Mo Suh, Chang-Hee Chung, Won Tae Park, Yong-Beom Choe, Jung-Yoon Shim, Seung Cheol Lee, Shin-Seok Han, Bok-Ghee Olsen, Nancy J. Karp, David R. Moser, Kathy Pons-Estel, Bernardo A. Wakeland, Edward K. James, Judith A. Harley, John B. Bae, Sang-Cheol Gaffney, Patrick M. Alarcón-Riquelme, Marta Looger, Loren L. Nath, Swapan K. Acevedo-Vasquez, Eduardo GENLES Network Group |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Kim-Howard, Xana Sun, Celi Molineros, Julio E. Maiti, Amit K. Chandru, Hema Adler, Adam Wiley, Graham B. Kaufman, Kenneth M. Kottyan, Leah Guthridge, Joel M. Rasmussen, Astrid Kelly, Jennifer Sánchez, Elena Raj, Prithvi Li, Quan-Zhen Bang, So-Young Lee, Hye-Soon Kim, Tae-Hwan Kang, Young Mo Suh, Chang-Hee Chung, Won Tae Park, Yong-Beom Choe, Jung-Yoon Shim, Seung Cheol Lee, Shin-Seok Han, Bok-Ghee Olsen, Nancy J. Karp, David R. Moser, Kathy Pons-Estel, Bernardo A. Wakeland, Edward K. James, Judith A. Harley, John B. Bae, Sang-Cheol Gaffney, Patrick M. Alarcón-Riquelme, Marta Looger, Loren L. Nath, Swapan K. Acevedo-Vasquez, Eduardo GENLES Network Group |
| dc.subject.es_PE.fl_str_mv |
Reumatología Lupus Eritematoso Sistémico Genética Humana |
| topic |
Reumatología Lupus Eritematoso Sistémico Genética Humana https://purl.org/pe-repo/ocde/ford#3.05.00 |
| dc.subject.ocde.es_PE.fl_str_mv |
https://purl.org/pe-repo/ocde/ford#3.05.00 |
| description |
Se realizó un análisis exhaustivo, utilizando un mapeo fino denso, para identificar variantes robustas e independientes que predisponen el Lupus Eritematoso Sistémico (LES), para predecir y validar los efectos moleculares de los alelos de riesgo de LES a través de la bioinformática, modelización molecular, y ensayos in vitro. Se analizó una gran cohorte multiétnica para investigar a fondo la asociación lupus eritematoso sistémico-NCF2 en población étnica diversa y para identificar etnicidad específica y variantes causales robustas. |
| publishDate |
2014 |
| dc.date.accessioned.none.fl_str_mv |
2019-04-26T15:28:58Z |
| dc.date.available.none.fl_str_mv |
2019-04-26T15:28:58Z |
| dc.date.issued.fl_str_mv |
2014 |
| dc.type.es_PE.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| dc.identifier.citation.es_PE.fl_str_mv |
Human Molecular Genetics |
| dc.identifier.uri.none.fl_str_mv |
https://hdl.handle.net/20.500.12959/490 |
| identifier_str_mv |
Human Molecular Genetics |
| url |
https://hdl.handle.net/20.500.12959/490 |
| dc.language.iso.es_PE.fl_str_mv |
eng |
| language |
eng |
| dc.rights.es_PE.fl_str_mv |
info:eu-repo/semantics/openAccess |
| dc.rights.uri.es_PE.fl_str_mv |
https://creativecommons.org/licenses/by-nc-nd/4.0/ |
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openAccess |
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https://creativecommons.org/licenses/by-nc-nd/4.0/ |
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application/pdf |
| dc.publisher.es_PE.fl_str_mv |
Seguro Social de Salud (EsSalud) |
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PE |
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Seguro Social de Salud (EsSalud) Repositorio Institucional EsSalud |
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reponame:ESSALUD-Institucional instname:Seguro Social de Salud instacron:ESSALUD |
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Seguro Social de Salud |
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ESSALUD |
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ESSALUD |
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ESSALUD-Institucional |
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ESSALUD-Institucional |
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Kim-Howard, XanaSun, CeliMolineros, Julio E.Maiti, Amit K.Chandru, HemaAdler, AdamWiley, Graham B.Kaufman, Kenneth M.Kottyan, LeahGuthridge, Joel M.Rasmussen, AstridKelly, JenniferSánchez, ElenaRaj, PrithviLi, Quan-ZhenBang, So-YoungLee, Hye-SoonKim, Tae-HwanKang, Young MoSuh, Chang-HeeChung, Won TaePark, Yong-BeomChoe, Jung-YoonShim, Seung CheolLee, Shin-SeokHan, Bok-GheeOlsen, Nancy J.Karp, David R.Moser, KathyPons-Estel, Bernardo A.Wakeland, Edward K.James, Judith A.Harley, John B.Bae, Sang-CheolGaffney, Patrick M.Alarcón-Riquelme, MartaLooger, Loren L.Nath, Swapan K.Acevedo-Vasquez, EduardoGENLES Network Group2019-04-26T15:28:58Z2019-04-26T15:28:58Z2014Human Molecular Geneticshttps://hdl.handle.net/20.500.12959/490Se realizó un análisis exhaustivo, utilizando un mapeo fino denso, para identificar variantes robustas e independientes que predisponen el Lupus Eritematoso Sistémico (LES), para predecir y validar los efectos moleculares de los alelos de riesgo de LES a través de la bioinformática, modelización molecular, y ensayos in vitro. Se analizó una gran cohorte multiétnica para investigar a fondo la asociación lupus eritematoso sistémico-NCF2 en población étnica diversa y para identificar etnicidad específica y variantes causales robustas.application/pdfengSeguro Social de Salud (EsSalud)PEinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/4.0/Seguro Social de Salud (EsSalud)Repositorio Institucional EsSaludreponame:ESSALUD-Institucionalinstname:Seguro Social de Saludinstacron:ESSALUDReumatologíaLupus Eritematoso SistémicoGenética Humanahttps://purl.org/pe-repo/ocde/ford#3.05.00Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populationsinfo:eu-repo/semantics/articleORIGINALAllelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations.pdfAllelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations.pdfapplication/pdf519154https://repositorio.essalud.gob.pe/bitstream/20.500.12959/490/1/Allelic%20heterogeneity%20in%20NCF2%20associated%20with%20systemic%20lupus%20erythematosus%20%28SLE%29%20susceptibility%20across%20four%20ethnic%20populations.pdf6d03918ba4eec99e9e317d8c6b2be659MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.essalud.gob.pe/bitstream/20.500.12959/490/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52TEXTAllelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations.pdf.txtAllelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations.pdf.txtExtracted texttext/plain76829https://repositorio.essalud.gob.pe/bitstream/20.500.12959/490/3/Allelic%20heterogeneity%20in%20NCF2%20associated%20with%20systemic%20lupus%20erythematosus%20%28SLE%29%20susceptibility%20across%20four%20ethnic%20populations.pdf.txta8e3dd6508d440ddb91404457467cb33MD53THUMBNAILAllelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations.pdf.jpgAllelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations.pdf.jpgGenerated Thumbnailimage/jpeg8339https://repositorio.essalud.gob.pe/bitstream/20.500.12959/490/4/Allelic%20heterogeneity%20in%20NCF2%20associated%20with%20systemic%20lupus%20erythematosus%20%28SLE%29%20susceptibility%20across%20four%20ethnic%20populations.pdf.jpg8dcbe4995152ce3553cb0835b319e9a5MD5420.500.12959/490oai:repositorio.essalud.gob.pe:20.500.12959/4902022-09-09 03:04:32.713Repositorio Seguro Social de Salud – ESSALUDbibliotecacentral@essalud.gob.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 |
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Nota importante:
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).
