Phytochemical Study of the Genus Salpichroa (Solanaceae), Chemotaxonomic Considerations, and Biological Evaluation in Prostate and Breast Cancer Cells

• Autores: Basso, AV, Gonzalez, SL, Barboza, GE, Careaga, VP, Calvo, JC, Sacca, PA, Nicotra, VE
• Formato: artículo
• Fecha de Publicación: 2017
• Institución: Consejo Nacional de Ciencia Tecnología e Innovación
• Repositorio: CONCYTEC-Institucional
• Lenguaje: inglés
• OAI Identifier: oai:repositorio.concytec.gob.pe:20.500.12390/1199
• Enlace del recurso: https://hdl.handle.net/20.500.12390/1199; https://doi.org/10.1002/cbdv.201700118
• Nivel de acceso: acceso abierto
• Materia: Química orgánica; Química física; https://purl.org/pe-repo/ocde/ford#1.04.03; https://purl.org/pe-repo/ocde/ford#1.04.01

Twelve Salpichroa taxa have been phytochemically analyzed. The chemical content of ca. 85% of the Salpichroa taxa is in agreement with molecular studies, which suggest that Salpichroa and Jaborosa, a genus considered morphologically close to Salpichroa, are distant in the systematic of the Solanoideae subfamily. Moreover, the in vitro cytotoxic activity of a set of natural salpichrolides and derivatives was examined against two prostate carcinoma cell lines and two human breast cancer cell lines. Several compounds showed moderate activity.