Biological activity and chemical characterization of Pouteria lucuma seeds: A possible use of an agricultural waste
Descripción del Articulo
The authors thank CONCYTEC (Convention 231-2015 FONDECYT) and FONDECYT REGULAR (Grant 1170871 and 1150745) for financial support.
| Autores: | , , , , , , |
|---|---|
| Formato: | artículo |
| Fecha de Publicación: | 2019 |
| Institución: | Consejo Nacional de Ciencia Tecnología e Innovación |
| Repositorio: | CONCYTEC-Institucional |
| Lenguaje: | inglés |
| OAI Identifier: | oai:repositorio.concytec.gob.pe:20.500.12390/538 |
| Enlace del recurso: | https://hdl.handle.net/20.500.12390/538 https://doi.org/10.1016/j.wasman.2019.03.055 |
| Nivel de acceso: | acceso abierto |
| Materia: | waste management Agricultural wastes Antioxidants Bioactivity Flavonoids Metabolites Organic acids Plants (botany) Agro-industrial wastes LC-MS/MS Lucuma Phenolics Pouteria Q Exactive Agriculture carboxylic acid flavonoid glycoside lansoprazole lipid methanol nucleoside nutraceutical nutrition supplement phenol phenol derivative plant extract Pouteria lucuma seed extract superoxide tannin unclassified drug agroindustry antioxidant biochemistry fruit mass spectrometry metabolite phenolic compound seed ABTS radical scavenging assay agro-industrial waste animal experiment animal model animal tissue antioxidant activity antiulcer activity Article biological activity chemical composition controlled study DPPH radical scavenging assay drug screening dry weight ferric reducing antioxidant power assay liquid chromatography-mass spectrometry nonhuman plant seed priority journal stomach protection Swiss Webster mouse Pouteria lucuma https://purl.org/pe-repo/ocde/ford#4.01.01 |
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| dc.title.none.fl_str_mv |
Biological activity and chemical characterization of Pouteria lucuma seeds: A possible use of an agricultural waste |
| title |
Biological activity and chemical characterization of Pouteria lucuma seeds: A possible use of an agricultural waste |
| spellingShingle |
Biological activity and chemical characterization of Pouteria lucuma seeds: A possible use of an agricultural waste Guerrero-Castillo P. waste management Agricultural wastes Antioxidants Bioactivity Flavonoids Metabolites Organic acids Plants (botany) Agro-industrial wastes LC-MS/MS Lucuma Phenolics Pouteria Q Exactive Agriculture carboxylic acid carboxylic acid flavonoid glycoside lansoprazole lansoprazole lipid methanol nucleoside nutraceutical nutraceutical nutrition supplement phenol phenol derivative plant extract Pouteria lucuma seed extract superoxide tannin tannin unclassified drug unclassified drug agroindustry antioxidant antioxidant biochemistry fruit fruit mass spectrometry metabolite phenolic compound seed ABTS radical scavenging assay ABTS radical scavenging assay agro-industrial waste animal experiment animal model animal tissue antioxidant activity antioxidant activity antiulcer activity Article biological activity biological activity chemical composition controlled study DPPH radical scavenging assay DPPH radical scavenging assay drug screening dry weight ferric reducing antioxidant power assay liquid chromatography-mass spectrometry metabolite nonhuman plant seed Pouteria priority journal stomach protection Swiss Webster mouse Pouteria Pouteria lucuma https://purl.org/pe-repo/ocde/ford#4.01.01 |
| title_short |
Biological activity and chemical characterization of Pouteria lucuma seeds: A possible use of an agricultural waste |
| title_full |
Biological activity and chemical characterization of Pouteria lucuma seeds: A possible use of an agricultural waste |
| title_fullStr |
Biological activity and chemical characterization of Pouteria lucuma seeds: A possible use of an agricultural waste |
| title_full_unstemmed |
Biological activity and chemical characterization of Pouteria lucuma seeds: A possible use of an agricultural waste |
| title_sort |
Biological activity and chemical characterization of Pouteria lucuma seeds: A possible use of an agricultural waste |
| author |
Guerrero-Castillo P. |
| author_facet |
Guerrero-Castillo P. Reyes S. Robles J. Simirgiotis M.J. Sepulveda B. Fernandez-Burgos R. Areche C. |
| author_role |
author |
| author2 |
Reyes S. Robles J. Simirgiotis M.J. Sepulveda B. Fernandez-Burgos R. Areche C. |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
Guerrero-Castillo P. Reyes S. Robles J. Simirgiotis M.J. Sepulveda B. Fernandez-Burgos R. Areche C. |
| dc.subject.none.fl_str_mv |
waste management |
| topic |
waste management Agricultural wastes Antioxidants Bioactivity Flavonoids Metabolites Organic acids Plants (botany) Agro-industrial wastes LC-MS/MS Lucuma Phenolics Pouteria Q Exactive Agriculture carboxylic acid carboxylic acid flavonoid glycoside lansoprazole lansoprazole lipid methanol nucleoside nutraceutical nutraceutical nutrition supplement phenol phenol derivative plant extract Pouteria lucuma seed extract superoxide tannin tannin unclassified drug unclassified drug agroindustry antioxidant antioxidant biochemistry fruit fruit mass spectrometry metabolite phenolic compound seed ABTS radical scavenging assay ABTS radical scavenging assay agro-industrial waste animal experiment animal model animal tissue antioxidant activity antioxidant activity antiulcer activity Article biological activity biological activity chemical composition controlled study DPPH radical scavenging assay DPPH radical scavenging assay drug screening dry weight ferric reducing antioxidant power assay liquid chromatography-mass spectrometry metabolite nonhuman plant seed Pouteria priority journal stomach protection Swiss Webster mouse Pouteria Pouteria lucuma https://purl.org/pe-repo/ocde/ford#4.01.01 |
| dc.subject.es_PE.fl_str_mv |
Agricultural wastes Antioxidants Bioactivity Flavonoids Metabolites Organic acids Plants (botany) Agro-industrial wastes LC-MS/MS Lucuma Phenolics Pouteria Q Exactive Agriculture carboxylic acid carboxylic acid flavonoid glycoside lansoprazole lansoprazole lipid methanol nucleoside nutraceutical nutraceutical nutrition supplement phenol phenol derivative plant extract Pouteria lucuma seed extract superoxide tannin tannin unclassified drug unclassified drug agroindustry antioxidant antioxidant biochemistry fruit fruit mass spectrometry metabolite phenolic compound seed ABTS radical scavenging assay ABTS radical scavenging assay agro-industrial waste animal experiment animal model animal tissue antioxidant activity antioxidant activity antiulcer activity Article biological activity biological activity chemical composition controlled study DPPH radical scavenging assay DPPH radical scavenging assay drug screening dry weight ferric reducing antioxidant power assay liquid chromatography-mass spectrometry metabolite nonhuman plant seed Pouteria priority journal stomach protection Swiss Webster mouse Pouteria Pouteria lucuma |
| dc.subject.ocde.none.fl_str_mv |
https://purl.org/pe-repo/ocde/ford#4.01.01 |
| description |
The authors thank CONCYTEC (Convention 231-2015 FONDECYT) and FONDECYT REGULAR (Grant 1170871 and 1150745) for financial support. |
| publishDate |
2019 |
| dc.date.accessioned.none.fl_str_mv |
2024-05-30T23:13:38Z |
| dc.date.available.none.fl_str_mv |
2024-05-30T23:13:38Z |
| dc.date.issued.fl_str_mv |
2019 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| dc.identifier.uri.none.fl_str_mv |
https://hdl.handle.net/20.500.12390/538 |
| dc.identifier.doi.none.fl_str_mv |
https://doi.org/10.1016/j.wasman.2019.03.055 |
| dc.identifier.scopus.none.fl_str_mv |
2-s2.0-85063595860 |
| url |
https://hdl.handle.net/20.500.12390/538 https://doi.org/10.1016/j.wasman.2019.03.055 |
| identifier_str_mv |
2-s2.0-85063595860 |
| dc.language.iso.none.fl_str_mv |
eng |
| language |
eng |
| dc.relation.ispartof.none.fl_str_mv |
Waste Management |
| dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.publisher.none.fl_str_mv |
Elsevier Ltd |
| publisher.none.fl_str_mv |
Elsevier Ltd |
| dc.source.none.fl_str_mv |
reponame:CONCYTEC-Institucional instname:Consejo Nacional de Ciencia Tecnología e Innovación instacron:CONCYTEC |
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Consejo Nacional de Ciencia Tecnología e Innovación |
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CONCYTEC |
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CONCYTEC |
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CONCYTEC-Institucional |
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CONCYTEC-Institucional |
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Repositorio Institucional CONCYTEC |
| repository.mail.fl_str_mv |
repositorio@concytec.gob.pe |
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1839175595627380736 |
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Publicationrp00926600rp00837400rp00922600rp00923600rp00921600rp00924600rp00925600Guerrero-Castillo P.Reyes S.Robles J.Simirgiotis M.J.Sepulveda B.Fernandez-Burgos R.Areche C.2024-05-30T23:13:38Z2024-05-30T23:13:38Z2019https://hdl.handle.net/20.500.12390/538https://doi.org/10.1016/j.wasman.2019.03.0552-s2.0-85063595860The authors thank CONCYTEC (Convention 231-2015 FONDECYT) and FONDECYT REGULAR (Grant 1170871 and 1150745) for financial support.Pouteria lucuma fruit is widely used to prepare cakes, ice creams and juice or also commercialized as pulp and flour. As result of this business thousands of tons of seeds are generated as an agricultural waste. This study presents the antioxidant and antiulcer activities, and the identification of secondary metabolites by UHPLC/ESI/MS/MS of an agroindustrial waste of Pouteria lucuma seeds. Fifty-nine compounds were tentatively identified including eight aminoacids, five organic acids, one nucleoside, five phenolic acids, five phenolic alcohols, nineteen flavonoids, six lipids, and seven unknowns in the methanol extract of P. lucuma seeds. The total phenolic content of the seeds was 52.82 ± 0.09 μmol GAE/g dry weight, while total flavonoid content was 5.99 ± 0.01 μmol Q/g dry weight. The antioxidant activity was 58.14 ± 0.05, 66.97 ± 0.00, 272.50 ± 0.00, and 67.02 ± 2.23 for the DPPH, ABTS, FRAP, and superoxide anion assays, respectively. The highest gastroprotective activity was obtained at 100 mg/kg (78%), which as higher than the positive control lansoprazole (75%). Our findings showed that P. lucuma seed extracts have moderate to high antioxidant activity and gastroprotective properties. Therefore, it was demostrated that lucuma seeds commonly eliminated as an agricultural industry waste, could be useful for the preparation of nutritional supplements.Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - ConcytecengElsevier LtdWaste Managementinfo:eu-repo/semantics/openAccesswaste managementAgricultural wastes-1Antioxidants-1Bioactivity-1Flavonoids-1Metabolites-1Organic acids-1Plants (botany)-1Agro-industrial wastes-1LC-MS/MS-1Lucuma-1Phenolics-1Pouteria-1Q Exactive-1Agriculture-1carboxylic acid-1carboxylic acid-1flavonoid-1glycoside-1lansoprazole-1lansoprazole-1lipid-1methanol-1nucleoside-1nutraceutical-1nutraceutical-1nutrition supplement-1phenol-1phenol derivative-1plant extract-1Pouteria lucuma seed extract-1superoxide-1tannin-1tannin-1unclassified drug-1unclassified drug-1agroindustry-1antioxidant-1antioxidant-1biochemistry-1fruit-1fruit-1mass spectrometry-1metabolite-1phenolic compound-1seed-1ABTS radical scavenging assay-1ABTS radical scavenging assay-1agro-industrial waste-1animal experiment-1animal model-1animal tissue-1antioxidant activity-1antioxidant activity-1antiulcer activity-1Article-1biological activity-1biological activity-1chemical composition-1controlled study-1DPPH radical scavenging assay-1DPPH radical scavenging assay-1drug screening-1dry weight-1ferric reducing antioxidant power assay-1liquid chromatography-mass spectrometry-1metabolite-1nonhuman-1plant seed-1Pouteria-1priority journal-1stomach protection-1Swiss Webster mouse-1Pouteria-1Pouteria lucuma-1https://purl.org/pe-repo/ocde/ford#4.01.01-1Biological activity and chemical characterization of Pouteria lucuma seeds: A possible use of an agricultural wasteinfo:eu-repo/semantics/articlereponame:CONCYTEC-Institucionalinstname:Consejo Nacional de Ciencia Tecnología e Innovacióninstacron:CONCYTEC#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#20.500.12390/538oai:repositorio.concytec.gob.pe:20.500.12390/5382024-05-30 15:35:40.676http://purl.org/coar/access_right/c_14cbinfo:eu-repo/semantics/closedAccessmetadata only accesshttps://repositorio.concytec.gob.peRepositorio Institucional CONCYTECrepositorio@concytec.gob.pe#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#<Publication xmlns="https://www.openaire.eu/cerif-profile/1.1/" id="70ce8193-b8db-44e9-be5a-4a51d9f975bd"> <Type xmlns="https://www.openaire.eu/cerif-profile/vocab/COAR_Publication_Types">http://purl.org/coar/resource_type/c_1843</Type> <Language>eng</Language> <Title>Biological activity and chemical characterization of Pouteria lucuma seeds: A possible use of an agricultural waste</Title> <PublishedIn> <Publication> <Title>Waste Management</Title> </Publication> </PublishedIn> <PublicationDate>2019</PublicationDate> <DOI>https://doi.org/10.1016/j.wasman.2019.03.055</DOI> <SCP-Number>2-s2.0-85063595860</SCP-Number> <Authors> <Author> <DisplayName>Guerrero-Castillo P.</DisplayName> <Person id="rp00926" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Reyes S.</DisplayName> <Person id="rp00837" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Robles J.</DisplayName> <Person id="rp00922" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Simirgiotis M.J.</DisplayName> <Person id="rp00923" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Sepulveda B.</DisplayName> <Person id="rp00921" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Fernandez-Burgos R.</DisplayName> <Person id="rp00924" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Areche C.</DisplayName> <Person id="rp00925" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> </Authors> <Editors> </Editors> <Publishers> <Publisher> <DisplayName>Elsevier Ltd</DisplayName> <OrgUnit /> </Publisher> </Publishers> <Keyword>waste management</Keyword> <Keyword>Agricultural wastes</Keyword> <Keyword>Antioxidants</Keyword> <Keyword>Bioactivity</Keyword> <Keyword>Flavonoids</Keyword> <Keyword>Metabolites</Keyword> <Keyword>Organic acids</Keyword> <Keyword>Plants (botany)</Keyword> <Keyword>Agro-industrial wastes</Keyword> <Keyword>LC-MS/MS</Keyword> <Keyword>Lucuma</Keyword> <Keyword>Phenolics</Keyword> <Keyword>Pouteria</Keyword> <Keyword>Q Exactive</Keyword> <Keyword>Agriculture</Keyword> <Keyword>carboxylic acid</Keyword> <Keyword>carboxylic acid</Keyword> <Keyword>flavonoid</Keyword> <Keyword>glycoside</Keyword> <Keyword>lansoprazole</Keyword> <Keyword>lansoprazole</Keyword> <Keyword>lipid</Keyword> <Keyword>methanol</Keyword> <Keyword>nucleoside</Keyword> <Keyword>nutraceutical</Keyword> <Keyword>nutraceutical</Keyword> <Keyword>nutrition supplement</Keyword> <Keyword>phenol</Keyword> <Keyword>phenol derivative</Keyword> <Keyword>plant extract</Keyword> <Keyword>Pouteria lucuma seed extract</Keyword> <Keyword>superoxide</Keyword> <Keyword>tannin</Keyword> <Keyword>tannin</Keyword> <Keyword>unclassified drug</Keyword> <Keyword>unclassified drug</Keyword> <Keyword>agroindustry</Keyword> <Keyword>antioxidant</Keyword> <Keyword>antioxidant</Keyword> <Keyword>biochemistry</Keyword> <Keyword>fruit</Keyword> <Keyword>fruit</Keyword> <Keyword>mass spectrometry</Keyword> <Keyword>metabolite</Keyword> <Keyword>phenolic compound</Keyword> <Keyword>seed</Keyword> <Keyword>ABTS radical scavenging assay</Keyword> <Keyword>ABTS radical scavenging assay</Keyword> <Keyword>agro-industrial waste</Keyword> <Keyword>animal experiment</Keyword> <Keyword>animal model</Keyword> <Keyword>animal tissue</Keyword> <Keyword>antioxidant activity</Keyword> <Keyword>antioxidant activity</Keyword> <Keyword>antiulcer activity</Keyword> <Keyword>Article</Keyword> <Keyword>biological activity</Keyword> <Keyword>biological activity</Keyword> <Keyword>chemical composition</Keyword> <Keyword>controlled study</Keyword> <Keyword>DPPH radical scavenging assay</Keyword> <Keyword>DPPH radical scavenging assay</Keyword> <Keyword>drug screening</Keyword> <Keyword>dry weight</Keyword> <Keyword>ferric reducing antioxidant power assay</Keyword> <Keyword>liquid chromatography-mass spectrometry</Keyword> <Keyword>metabolite</Keyword> <Keyword>nonhuman</Keyword> <Keyword>plant seed</Keyword> <Keyword>Pouteria</Keyword> <Keyword>priority journal</Keyword> <Keyword>stomach protection</Keyword> <Keyword>Swiss Webster mouse</Keyword> <Keyword>Pouteria</Keyword> <Keyword>Pouteria lucuma</Keyword> <Abstract>Pouteria lucuma fruit is widely used to prepare cakes, ice creams and juice or also commercialized as pulp and flour. As result of this business thousands of tons of seeds are generated as an agricultural waste. This study presents the antioxidant and antiulcer activities, and the identification of secondary metabolites by UHPLC/ESI/MS/MS of an agroindustrial waste of Pouteria lucuma seeds. Fifty-nine compounds were tentatively identified including eight aminoacids, five organic acids, one nucleoside, five phenolic acids, five phenolic alcohols, nineteen flavonoids, six lipids, and seven unknowns in the methanol extract of P. lucuma seeds. The total phenolic content of the seeds was 52.82 ± 0.09 μmol GAE/g dry weight, while total flavonoid content was 5.99 ± 0.01 μmol Q/g dry weight. The antioxidant activity was 58.14 ± 0.05, 66.97 ± 0.00, 272.50 ± 0.00, and 67.02 ± 2.23 for the DPPH, ABTS, FRAP, and superoxide anion assays, respectively. The highest gastroprotective activity was obtained at 100 mg/kg (78%), which as higher than the positive control lansoprazole (75%). Our findings showed that P. lucuma seed extracts have moderate to high antioxidant activity and gastroprotective properties. Therefore, it was demostrated that lucuma seeds commonly eliminated as an agricultural industry waste, could be useful for the preparation of nutritional supplements.</Abstract> <Access xmlns="http://purl.org/coar/access_right" > </Access> </Publication> -1 |
| score |
13.439101 |
Nota importante:
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).
