Program for Determining the Dosimetric Contribution of Tc-99m Biokinetics in Estimating the Dose to the Heart of a Male Adult

• Autores: Morales-Nizama, Rosa Adela, Gallozzo-Cárdenas, Moisés Miguel, Chinchay-Espino, Héctor Almanzor, Murga-Torres, Emzon, Alvarez-Escobedo, Amilu M., Nazario-Naveda, Renny
• Formato: artículo
• Fecha de Publicación: 2023
• Institución: Universidad Autónoma del Perú
• Repositorio: AUTONOMA-Institucional
• Lenguaje: inglés
• OAI Identifier: oai:repositorio.autonoma.edu.pe:20.500.13067/3483
• Enlace del recurso: https://hdl.handle.net/20.500.13067/3483; https://doi.org/10.4103/jmp.jmp_79_23
• Nivel de acceso: acceso abierto
• Materia: Biokinetics; Internal dosimetry; Medical internal radiation dose formalism; Tc‑99m; https://purl.org/pe-repo/ocde/ford#2.07.00

Purpose: To calculate the contribution of absorbed dose by organs in the biokinetics of Tc-99m when used for radiodiagnosis of the adult male heart employing a Matlab program. Methods: The absorbed self-dose of the adult male heart and absorbed dose by organs in the biokinetics of the heart when administering Tc-99m are estimated using the MIRD formalism and the Cristy-Eckerman representation, which have been employed to develop the algorithm in Matlab. Results: The results indicate that electron capture emissions of 1.446 (mGy/MBq) and Auger electrons of 0.062 (mGy/MBq) are entirely directed towards the target organ (heart) and contribute 29.33% and 1.25% respectively to its total dose. Additionally, the dosimetric contributions of biokinetic organs correspond to characteristic radiation emissions and gamma photons at 2.578 (mGy/MBq) for Tc-99m, representing 52.29% of its total dose. Conclusion: These dosimetric contributions are significant in estimating the total absorbed dose by the heart in adult males and should not be disregarded.