Gastroesophageal reflux disease as a factor associated with bronchial asthma in the pediatric population
Descripción del Articulo
Objective: To determine the relationship between gastroesophageal reflux disease and bronchial asthma in the pediatric population of the National Children's Hospital Breña headquarters between the years 2017-2018. Methods: An analytical observational study of cases and controls was not matched,...
| Autores: | , , , , |
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| Formato: | artículo |
| Fecha de Publicación: | 2020 |
| Institución: | Universidad Ricardo Palma |
| Repositorio: | Revista URP - Revista de la Facultad de Medicina Humana |
| Lenguaje: | español inglés |
| OAI Identifier: | oai:oai.revistas.urp.edu.pe:article/2918 |
| Enlace del recurso: | http://revistas.urp.edu.pe/index.php/RFMH/article/view/2918 |
| Nivel de acceso: | acceso abierto |
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Revista URP - Revista de la Facultad de Medicina Humana |
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Gastroesophageal reflux disease as a factor associated with bronchial asthma in the pediatric populationEnfermedad por reflujo gastroesofágico como factor asociado a asma bronquial en población pediátricaRicra, RafaelRoque, Juan CarlosAlburqueque-Melgarejo, JosephRicra, PedroSaldaña, ClaudiaObjective: To determine the relationship between gastroesophageal reflux disease and bronchial asthma in the pediatric population of the National Children's Hospital Breña headquarters between the years 2017-2018. Methods: An analytical observational study of cases and controls was not matched, with a ratio of 1 case to 2 controls, with a total of 45 cases and 90 controls, a simple random probability sampling was performed, with a retrospective collection for the variables bronchial asthma, GERD, GERDinduced esophagitis, prematurity, interrupted breastfeeding, sex and age. A bivariate and multiple logistic regression model was performed to obtain the Odds Ratio for the strength of association. Results: A statistically significant difference was found for GERD (p = 0.002), being 33.33% and 11.11% for cases and controls, as well as for interrupted lactation (p = 0.013); by multiple logistic regression analysis the variables GERD (OR 4.27, p = 0.003, CI 1.64-10.92) and interrupted breastfeeding (OR 2.74, P = 0.011, CI 1.26-5.97 ) presented a relationship for bronchial asthma. Conclusion: A relationship was found between GERD and bronchial asthma which can be extrapolated to the pediatric population of the city of Lima, this is the first article published in this regard at the national level, prospective studies are recommended to determine causality.Objetivo: Determinar la relación entre enfermedad por reflujo gastroesofágico y asma bronquial en la población pediátrica del hospital Nacional del niño sede Breña entre los años 2017-2018. Métodos: Se realizó un estudio observacional analítico tipo casos y controles no emparejado de razón 1 caso para 2 controles, con un total de 45 casos y 90 controles, se realizó un muestreo probabilístico aleatorio simple, con una recolección retrospectiva para las variables asma bronquial, ERGE, esofagitis inducida por ERGE, prematuridad, lactancia materna interrumpida, sexo y edad. Se realizó un modelo de regresión logística bivariado y múltiple para la obtención del Odds Ratio para la fuerza de asociación. Resultados: Se encontró una diferencia estadísticamente significativa para ERGE (p=0,002), siendo 33,33% y 11,11% para los casos y controles, así como para lactancia interrumpida (p=0,013); por análisis de regresión logística múltiple las variables ERGE (OR 4,27, p=0,003, IC 1,64-10,92) y lactancia materna interrumpida (OR 2,74, P=0,011, IC 1,26-5,97) presentaron relación para asma bronquial. Conclusión: Se encontró una relación entre ERGE y asma bronquial la cual puede ser extrapolada a la población pediátrica de la ciudad de Lima, este es el primer artículo publicado al respecto a nivel nacional, se recomiendan estudios prospectivos para determinar causalidad.Universidad Ricardo Palma2020-03-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdftext/htmlapplication/pdftext/htmlhttp://revistas.urp.edu.pe/index.php/RFMH/article/view/291810.25176/RFMH.v20i2.2918Revista de la Facultad de Medicina Humana; Vol 20 No 2 (2020): Revista de la Facultad de Medicina Humana; 1Revista de la Facultad de Medicina Humana; Vol. 20 Núm. 2 (2020): Revista de la Facultad de Medicina Humana; 12308-05311814-5469reponame:Revista URP - Revista de la Facultad de Medicina Humanainstname:Universidad Ricardo Palmainstacron:URPspaenghttp://revistas.urp.edu.pe/index.php/RFMH/article/view/2918/3070http://revistas.urp.edu.pe/index.php/RFMH/article/view/2918/3071http://revistas.urp.edu.pe/index.php/RFMH/article/view/2918/3072http://revistas.urp.edu.pe/index.php/RFMH/article/view/2918/3073info:eu-repo/semantics/openAccess2021-06-02T16:10:24Zmail@mail.com - |
| dc.title.none.fl_str_mv |
Gastroesophageal reflux disease as a factor associated with bronchial asthma in the pediatric population Enfermedad por reflujo gastroesofágico como factor asociado a asma bronquial en población pediátrica |
| title |
Gastroesophageal reflux disease as a factor associated with bronchial asthma in the pediatric population |
| spellingShingle |
Gastroesophageal reflux disease as a factor associated with bronchial asthma in the pediatric population Ricra, Rafael |
| title_short |
Gastroesophageal reflux disease as a factor associated with bronchial asthma in the pediatric population |
| title_full |
Gastroesophageal reflux disease as a factor associated with bronchial asthma in the pediatric population |
| title_fullStr |
Gastroesophageal reflux disease as a factor associated with bronchial asthma in the pediatric population |
| title_full_unstemmed |
Gastroesophageal reflux disease as a factor associated with bronchial asthma in the pediatric population |
| title_sort |
Gastroesophageal reflux disease as a factor associated with bronchial asthma in the pediatric population |
| dc.creator.none.fl_str_mv |
Ricra, Rafael Roque, Juan Carlos Alburqueque-Melgarejo, Joseph Ricra, Pedro Saldaña, Claudia |
| author |
Ricra, Rafael |
| author_facet |
Ricra, Rafael Roque, Juan Carlos Alburqueque-Melgarejo, Joseph Ricra, Pedro Saldaña, Claudia |
| author_role |
author |
| author2 |
Roque, Juan Carlos Alburqueque-Melgarejo, Joseph Ricra, Pedro Saldaña, Claudia |
| author2_role |
author author author author |
| dc.description.none.fl_txt_mv |
Objective: To determine the relationship between gastroesophageal reflux disease and bronchial asthma in the pediatric population of the National Children's Hospital Breña headquarters between the years 2017-2018. Methods: An analytical observational study of cases and controls was not matched, with a ratio of 1 case to 2 controls, with a total of 45 cases and 90 controls, a simple random probability sampling was performed, with a retrospective collection for the variables bronchial asthma, GERD, GERDinduced esophagitis, prematurity, interrupted breastfeeding, sex and age. A bivariate and multiple logistic regression model was performed to obtain the Odds Ratio for the strength of association. Results: A statistically significant difference was found for GERD (p = 0.002), being 33.33% and 11.11% for cases and controls, as well as for interrupted lactation (p = 0.013); by multiple logistic regression analysis the variables GERD (OR 4.27, p = 0.003, CI 1.64-10.92) and interrupted breastfeeding (OR 2.74, P = 0.011, CI 1.26-5.97 ) presented a relationship for bronchial asthma. Conclusion: A relationship was found between GERD and bronchial asthma which can be extrapolated to the pediatric population of the city of Lima, this is the first article published in this regard at the national level, prospective studies are recommended to determine causality. Objetivo: Determinar la relación entre enfermedad por reflujo gastroesofágico y asma bronquial en la población pediátrica del hospital Nacional del niño sede Breña entre los años 2017-2018. Métodos: Se realizó un estudio observacional analítico tipo casos y controles no emparejado de razón 1 caso para 2 controles, con un total de 45 casos y 90 controles, se realizó un muestreo probabilístico aleatorio simple, con una recolección retrospectiva para las variables asma bronquial, ERGE, esofagitis inducida por ERGE, prematuridad, lactancia materna interrumpida, sexo y edad. Se realizó un modelo de regresión logística bivariado y múltiple para la obtención del Odds Ratio para la fuerza de asociación. Resultados: Se encontró una diferencia estadísticamente significativa para ERGE (p=0,002), siendo 33,33% y 11,11% para los casos y controles, así como para lactancia interrumpida (p=0,013); por análisis de regresión logística múltiple las variables ERGE (OR 4,27, p=0,003, IC 1,64-10,92) y lactancia materna interrumpida (OR 2,74, P=0,011, IC 1,26-5,97) presentaron relación para asma bronquial. Conclusión: Se encontró una relación entre ERGE y asma bronquial la cual puede ser extrapolada a la población pediátrica de la ciudad de Lima, este es el primer artículo publicado al respecto a nivel nacional, se recomiendan estudios prospectivos para determinar causalidad. |
| description |
Objective: To determine the relationship between gastroesophageal reflux disease and bronchial asthma in the pediatric population of the National Children's Hospital Breña headquarters between the years 2017-2018. Methods: An analytical observational study of cases and controls was not matched, with a ratio of 1 case to 2 controls, with a total of 45 cases and 90 controls, a simple random probability sampling was performed, with a retrospective collection for the variables bronchial asthma, GERD, GERDinduced esophagitis, prematurity, interrupted breastfeeding, sex and age. A bivariate and multiple logistic regression model was performed to obtain the Odds Ratio for the strength of association. Results: A statistically significant difference was found for GERD (p = 0.002), being 33.33% and 11.11% for cases and controls, as well as for interrupted lactation (p = 0.013); by multiple logistic regression analysis the variables GERD (OR 4.27, p = 0.003, CI 1.64-10.92) and interrupted breastfeeding (OR 2.74, P = 0.011, CI 1.26-5.97 ) presented a relationship for bronchial asthma. Conclusion: A relationship was found between GERD and bronchial asthma which can be extrapolated to the pediatric population of the city of Lima, this is the first article published in this regard at the national level, prospective studies are recommended to determine causality. |
| publishDate |
2020 |
| dc.date.none.fl_str_mv |
2020-03-25 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
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article |
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publishedVersion |
| dc.identifier.none.fl_str_mv |
http://revistas.urp.edu.pe/index.php/RFMH/article/view/2918 10.25176/RFMH.v20i2.2918 |
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http://revistas.urp.edu.pe/index.php/RFMH/article/view/2918 |
| identifier_str_mv |
10.25176/RFMH.v20i2.2918 |
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spa eng |
| language |
spa eng |
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http://revistas.urp.edu.pe/index.php/RFMH/article/view/2918/3070 http://revistas.urp.edu.pe/index.php/RFMH/article/view/2918/3071 http://revistas.urp.edu.pe/index.php/RFMH/article/view/2918/3072 http://revistas.urp.edu.pe/index.php/RFMH/article/view/2918/3073 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf text/html application/pdf text/html |
| dc.publisher.none.fl_str_mv |
Universidad Ricardo Palma |
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Universidad Ricardo Palma |
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Revista de la Facultad de Medicina Humana; Vol 20 No 2 (2020): Revista de la Facultad de Medicina Humana; 1 Revista de la Facultad de Medicina Humana; Vol. 20 Núm. 2 (2020): Revista de la Facultad de Medicina Humana; 1 2308-0531 1814-5469 reponame:Revista URP - Revista de la Facultad de Medicina Humana instname:Universidad Ricardo Palma instacron:URP |
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mail@mail.com |
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La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).