Objective: This study evaluated the use of vitamin E and phytogenic compounds in drinking water on growth performance, oxidative stress, and immune status of piglets fed peroxidized lipids. Materials and Methods: In a 35-d study, 21-d-old weaned piglets (n = 96; 6.10 +/- 0.64 kg of BW) were assigned within sex and BW blocks to 1 of 4 treatments, using 24 pens (4 pigs per pen; 6 replications per treatment). Diets contained either 6% soybean oil or 6% peroxidized soybean oil. Pigs fed peroxidized soybean oil received drinking water without (control) or with supplemental vitamin E (100 IU/L of RRR-alpha-tocopherol) or phytogenic compounds (60 mu L/L for wk 1 and 30 mu L/L for wk 2 to 5). Results and Discussion: Peroxidized soybean oil decreased (P < 0.001) final BW (18.2 vs. 21.6 kg) and ADG (346 vs. 441 g/d) and tended to decrease ADFI (P = 0.14; 542 vs. 617 g/d) and G:F (P = 0.07; 645 vs....