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Childhood Maltreatment and Somatic Symptoms in Adulthood: Establishing a New Research Pathway

Publicado por
Lüönd, Antonia M., Ayas, Görkem, Bachem, Rahel, Carranza-Neira, Julia, Eberle, David J., Fares-Otero, Natalia E., Hashim, Mohammad, Iqbal, Naved, Jenkins, Dan, Kamari Songhorabadi, Saman, Ledermann, Katharina, Makhashvili, Nino, Martin Soelch, Chantal, Nebioğlu, Ertaç, Oe, Misari, Olayinka, Juliet N., Olff, Miranda, Picot, Laura, Seedat, Soraya, Tandon, Tanya, Wadji, Dany L., Womersley, Jacqueline S., Schnyder, Ulrich, Sar, Vedat, Pfaltz, Monique C., Ceylan, Deniz

Publicado 2025

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Background: Somatic symptoms, such as chronic pain, fatigue, and gastrointestinal disturbances, are commonly reported in individuals with a history of childhood maltreatment (CM), which includes various forms of abuse and neglect experienced before age 18. Although CM is strongly associated with somatic symptoms, the specific relationships between CM subtypes and these symptoms, as well as the mechanisms connecting them, remain insufficiently understood. This review examines the complex interaction between CM and somatic symptoms, which often coexist with mental disorders and significantly impact quality of life and healthcare systems. Summary: Somatic symptoms, frequently a mix of "explained" and "unexplained" conditions, are associated with personal distress and pose diagnostic challenges. CM has been linked to these symptoms through neurobiological mechanisms, such as HPA axis dysregu...