La desensibilización farmacológica induce un estado temporal de hiposensibilidad a un medicamento que se realiza a pacientes con reacciones mediadas por Inmunoglobulina E. Reporte de caso: Presentamos el caso de un paciente con exacerbación respiratoria de fibrosis quística que presentó hipersensibilidad inmediata a colistina, un antibiótico esencial para su tratamiento, tanto por la sensibilidad del microorganismo, como la falta de disponibilidad de otros medicamentos. Se realizó el procedimiento en Unidad de Cuidados Intensivos de forma exitosa y el paciente completó el esquema del tratamiento. Conclusión: Actualmente el paciente se encuentra en tratamiento específico para su enfermedad de fondo y no ha presentado nuevos episodios de exacerbación ni neumonías.

Introduction: Pharmacological desensitization induces a temporary hyposensitivity to the causative drug in patients with Immunoglobulin E-mediated drug reactions. Case of report: We present the case of a patient with respiratory exacerbation of cystic fibrosis who presented immediate hypersensitivity to colistin, an essential antibiotic for its treatment—both due to the sensitivity of the microorganism and the lack of availability of other drugs. The procedure was successfully performed in the Intensive Care Unit, and the patient completed the treatment schedule. Conclusion: Currently, the patient is undergoing specific treatment for his underlying disease and has not presented any new episodes of exacerbation or pneumonia.

Determina los factores asociados a la calidad de vida relacionada a salud de los niños con inmunodeficiencias primarias atendidos durante la pandemia de la enfermedad por coronavirus (COVID-19) en el Hospital Nacional Edgardo Rebagliati Martins y el Hospital Nacional Guillermo Almenara Irigoyen. El presente estudio es observacional y analítico. Se invitó a la totalidad de pacientes, 63 sujetos, de ambos hospitales con inmunodeficiencias primarias en el rango de edad de 2 a 17 años en los que se aplicó el cuestionario de calidad de vida relacionado a salud PEDS-QL 4.0. Asimismo, se recolectó información clínica para evaluar los factores asociados y se comparó los puntajes de CVRS con pacientes con asma bronquial. 50 niños con inmunodeficiencias primarias participaron en el estudio (tasa de respuesta 79,37%) y 102 niños con asma fueron incluidos para comparar los puntajes de cal...

No description

Introduction: According to the millennium development goals, our country must reduce maternal mortality rate in 75%, and the Strategic National Action Plan for Reduction of Maternal and Perinatal Mortality considers reducing the possibilities of complications during pregnancy, labor and puerperium by recognizing the danger signs during pregnancy. Objectives: To determine the level of knowledge and practices on danger signs in pregnant women. Design: Descriptive study. Setting: Hospital Nacional Docente Madre-Niño San Bartolome, Lima, Peru. Patients: Pregnant women in hospitalization and outpatient consultation during June 2013. Interventions: A survey was administered to evaluate knowledge and practices on danger signs during pregnancy. Chi-square test bivariate analysis was used; odds ratio assessed association strength. Main outcome measures: With/without knowledge and practi...

Introduction: According to the millennium development goals, our country must reduce maternal mortality rate in 75%, and the Strategic National Action Plan for Reduction of Maternal and Perinatal Mortality considers reducing the possibilities of complications during pregnancy, labor and puerperium by recognizing the danger signs during pregnancy. Objectives: To determine the level of knowledge and practices on danger signs in pregnant women. Design: Descriptive study. Setting: Hospital Nacional Docente Madre-Niño San Bartolome, Lima, Peru. Patients: Pregnant women in hospitalization and outpatient consultation during June 2013. Interventions: A survey was administered to evaluate knowledge and practices on danger signs during pregnancy. Chi-square test bivariate analysis was used; odds ratio assessed association strength. Main outcome measures: With/without knowledge and practi...