Resumen del Proyecto: Fármaco inhibidor de la proteína s1-spike del virus sars-cov-2 a partir de quimera hsace2/fago t4 con base hexagonal suministrable vía oral inhalatoria

Objective: To analyze the trends in gastric cancer mortality in Peru from 1995 to 2013 and their differences by sex, age groups, natural regions and political regions. Materials and methods: Ecological time-series study based on 49,690 death records from the Ministry of Health, from 1995 to 2013; Crude, specific and standardized mortality rates (SMR) were calculated by year; according to sex; age group; political and geographic regions, to analyze trends by estimating joinpoints and annual percentage changes (CPA); using segmented regression models, adjusted using Joinpoint Regression Desktop software version 4.5.0.0, Results: The SMR trend due to gastric cancer in Peru was decreasing, falling from 16.1 x 100 000 inhabitants. in 1995 to 11.4 x 100 000 inhabitants. in 2013 (CPA: -2.3), observing decreasing trends by age groups, sex and in 17 of 25 political regions. Differences were found...

Objective: To analyze the trends in gastric cancer mortality in Peru from 1995 to 2013 and their differences by sex, age groups, natural regions and political regions. Materials and methods: Ecological time-series study based on 49,690 death records from the Ministry of Health, from 1995 to 2013; Crude, specific and standardized mortality rates (SMR) were calculated by year; according to sex; age group; political and geographic regions, to analyze trends by estimating joinpoints and annual percentage changes (CPA); using segmented regression models, adjusted using Joinpoint Regression Desktop software version 4.5.0.0, Results: The SMR trend due to gastric cancer in Peru was decreasing, falling from 16.1 x 100 000 inhabitants. in 1995 to 11.4 x 100 000 inhabitants. in 2013 (CPA: -2.3), observing decreasing trends by age groups, sex and in 17 of 25 political regions. Differences were found...

Analiza las tendencias de la mortalidad por cáncer gástrico en el Perú. El estudio es descriptivo, longitudinal sobre la base de 49,690 registros de defunción del Ministerio de Salud, de 1995 al 2013; se calcularon las tasas brutas, estandarizadas y específicas de mortalidad por año, sexo, grupo de edad, región política y región natural para analizar sus tendencias, joinpoints y cambios de porcentaje anual (CPA) utilizando el software Joinpoint Regression Program versión 4.3.1.0, La tendencia de mortalidad por cáncer gástrico en el Perú fue decreciente (CPA:-2.3) y estadísticamente significativa (p<0.05), pero muestra disparidades, un decremento más acelerado en mujeres (CPA -2.5) versus hombres (-2.0) y en grupos de edad (CPA para 75 - 79 años: -2.57 versus CPA para 40 – 44: - 1.39); se identifica tres áreas de alta mortalidad: Andes centrales (Huancavelica, Huánuco,...

Objective: To determine the epidemiological, clinical and pathological characteristics of lymphoma cases in Cayetano Heredia National Hospital. Material and methods: We conducted a descriptive and retrospective case series including 433 patients with lymphoma diagnosed from 1998 to 2008. Results: Average age of patients was 44.8 years, and 60.04% were male. Most frequent birthplace and living area was Lima, with 61.5% and 90% of all patients, respectively. Most frequent symptoms were weight loss and lymph node enlargement (40.5% and 3,7%, respectively). More than half of all patients (55.08%) were in I-II clinical stages. The most frequent location of the disease was in the lymph nodes (55.1%). Extranodal locations were the gastrointestinal tract (15.2%) and the skin (10.8%). The B immunophenotype corresponded to 57.8% o all non-Hodgkin lymphoma cases, and the most common ...

Objective: To determine the epidemiological, clinical and pathological characteristics of lymphoma cases in Cayetano Heredia National Hospital. Material and methods: We conducted a descriptive and retrospective case series including 433 patients with lymphoma diagnosed from 1998 to 2008. Results: Average age of patients was 44.8 years, and 60.04% were male. Most frequent birthplace and living area was Lima, with 61.5% and 90% of all patients, respectively. Most frequent symptoms were weight loss and lymph node enlargement (40.5% and 3,7%, respectively). More than half of all patients (55.08%) were in I-II clinical stages. The most frequent location of the disease was in the lymph nodes (55.1%). Extranodal locations were the gastrointestinal tract (15.2%) and the skin (10.8%). The B immunophenotype corresponded to 57.8% o all non-Hodgkin lymphoma cases, and the most common ...

Resumen del Proyecto: Detección rápida del coronavirus SARS-COV-2 utilizando como target el receptor ACE2, inmovilizado con una cola de cisteína en un electrodo de oro, usando técnicas de espectroscopía de impedancia