Adhesive systems are used in daily clinical practice; however, the main disadvantage is polymerization shrinkage, which could lead to microleakage, plaque accumulation, secondary caries, and hypersensitivity. For this reason, antimicrobial agents have been incorporated, such as light-curing quaternary ammonium methacrylate, fluoride ion-releasing glass fillers, pyrogallol, and nanoparticles of silver, calcium, and fluorinated graphene. In recent years, some of these have been shown to have good antimicrobial effectiveness and, in turn, do not interfere with adhesion in restorations. Thus, these antimicrobial adhesive systems could contribute to better long-term results. The best-performing nanoparticles were amorphous calcium phosphate and silver nanoparticles.

The research addresses the budget execution process, whose objective was to measure the level of budget execution for local government projects in the Puno region in the periods 2019 to 2021, with a quantitative, non-experimental methodology with a crosssectional descriptive research design applied For the 110 local governments, a documentary analysis sheet was used to identify the level of expenditure execution, using the MEF range: (84-00=deficient) (89-85 =regular) (94-85=good) ( 100-95=Very good), the institutional performance is qualified according to the range, where the following result was obtained: the average execution of public spending in projects of the municipalities in periods 2019 to 2021, is deficient; it is below and equal to 84% of the budget execution efficiency level. In the 2019 period, the average execution of project spending is 70.4% as of December 31, in 2019, 6...