Microscopic colitis (MC) is a chronic inflammatory bowel disease characterized by watery diarrhea and a macroscopically normal-appearing colonic mucosa on colonoscopy. It is classified into lymphocytic colitis (LC) and collagenous colitis (CC). Its incidence has increased in developed countries, but data from Latin America remain limited. We present the case of a 65-year-old woman with fibromyalgia and recent use of duloxetine, who presented with chronic diarrhea. Colonoscopy revealed edematous mucosa with loss of vascular transparency, deep furrows with a cobblestone-like appearance, and an open dot-like surface pattern. Histopathological analysis confirmed a diagnosis of LC. After discontinuing duloxetine, the diarrhea resolved spontaneously without the need for corticosteroids. Although MC has traditionally been described as presenting with a normal-appearing colonic mucosa, studies h...

Endoscopic intermuscular dissection (EID) emerges as an alternative for the treatment of patients with rectal lesions with suspected deep invasion or with extensive fibrosis which are not candidates for endoscopic submucosal dissection (ESD). In EID the dissection is performed between the inner (circular) and outer (longitudinal) layers of the muscularis propia. We present the case of a patient successfully treated with EID technique. 54-year-old female patient with a history sessile adenomatous lesion of the rectum of approximately 40 mm resected with conventional endoscopic mucosal resection technique. She presented a recurrence of the lesion on the prior resection scar. EID was performed on the scar of prior endoscopic resection, accessing and exposing the intermuscular plane. En bloc resection of the lesion was achieved with negative histological lateral and deep margins, fulfilling ...

Introduction: Esophageal adenocarcinoma (EAC) is increasing in Western countries, and Barrett’s esophagus (BE) represents its only known premalignant condition. BE affects approximately 1–2% of the general population and up to 14% of patients with gastroesophageal reflux disease (GERD). Data from Latin America and Chile remain limited. Objectives: To determine the prevalence of BE, the neoplasia detection rate (NDR), and the endoscopic quality criteria associated with neoplasia detection in a Chilean university center. Materials and methods: A longitudinal cohort study including all patients with BE identified among upper gastrointestinal endoscopies performed at the Red de Salud UC CHRISTUS between January 2015 and December 2022. Patients with a history of other digestive neoplasms or referred with previously diagnosed BE/EAC were excluded. Demographic, endoscopic, and histopatholog...