El presente trabajo titulado, “Efecto insecticida y composición química del extracto hidroalcohólico de Capsicum pubescens Ruiz & Pav, sobre Epitrix spp. en condiciones de laboratorio”, tuvo tres (03) objetivos; la primera relacionada al efecto del extracto hidroalcóhilico de rocoto en diferentes concentraciones y tiempos, a la vez comprender la composición química y por último determinar el costo productivo de Capsicum pubescens Ruiz & Pav. Dentro de la metodología se utilizó el diseño en bloque completamente al azar (DBCA), 4 dosis por 5 tiempos de evaluación 4A x 5B (a1= 5.0%, a2= 2.5%, a3= 1.0%, a4= 0.0%(testigo), (b1=06 horas dda, b2= 12 horas dda, b3 = 24 horas dda, b4 = 48 horas dda y b5 = 72 horas dda) con 3 repeticiones. De acuerdo a los resultados obtenidos se encontró un promedio de 12.33 % a las 72 horas después de la aplicación con una mortalidad al 95% (19...

Introduction: Esophageal adenocarcinoma (EAC) is increasing in Western countries, and Barrett’s esophagus (BE) represents its only known premalignant condition. BE affects approximately 1–2% of the general population and up to 14% of patients with gastroesophageal reflux disease (GERD). Data from Latin America and Chile remain limited. Objectives: To determine the prevalence of BE, the neoplasia detection rate (NDR), and the endoscopic quality criteria associated with neoplasia detection in a Chilean university center. Materials and methods: A longitudinal cohort study including all patients with BE identified among upper gastrointestinal endoscopies performed at the Red de Salud UC CHRISTUS between January 2015 and December 2022. Patients with a history of other digestive neoplasms or referred with previously diagnosed BE/EAC were excluded. Demographic, endoscopic, and histopatholog...

Objetivo. Determinar el valor pronóstico del descenso absoluto de la porción N-terminal del propéptido natriurético tipo B (NT–proBNP) para prevenir menos eventos clínicos en la población del estudio CLUSTER-HF (eficacia del ultrasonido pulmonar para guiar la terapia y prevenir las rehospitalizaciones en insuficiencia cardiaca). Materiales y métodos. El presente estudio fue realizado en un subgrupo de 94 pacientes con información disponible de NT-proBNP al alta hospitalaria y previo a la aleatorización del estudio CLUSTER-HF. El objetivo primario del estudio fue determinar el valor pronóstico de descenso absoluto de NT - pro-BNP por debajo del cual se prediga menos eventos de muerte por todas las causas, visitas a urgencias y rehospitalización por insuficiencia cardiaca a 180 días. Resultados. El descenso absoluto de NT-proBNP por debajo de 3 350 pg/mL tiene una capacidad d...

Objective. The purpose of this study is to determine the prognostic value of the absolute decrease in the N-terminal portion of pro-B-type natriuretic peptide (NT-proBNP) to prevent fewer clinical events, in the population of CLUSTER-HF (efficacy of ultrasound lung to guide therapy and prevent readmissions in heart failure). Materials and methods. This study was conducted in a subgroup of ninety-four patients with available NT-proBNP information at hospital discharge and prior to randomization in the CLUSTER-HF study. The primary objective of the study was to determine the prognostic value of absolute NT-proBNP decline below which fewer events of all-cause death, emergency room visits, and rehospitalization for heart failure at 180 days. Results. The absolute decrease in NT-proBNP below 3,350 pg/mL has a moderate discriminative capacity with AUC= 0.602, with a prognostic value in the com...

Objective. Acute myocardial infarction-related cardiogenic shock (AMI-CS) is often accompanied by tachycardia, which, in turn, increases myocardial oxygen consumption and hinders the use of ventricular assist devices, such as intra-aortic balloon pump. Evidence suggests that ivabradine may reduce heart rate (HR) without affecting other hemodynamic parameters. The aim of the present study was to determine the effect of ivabradine on reducing HR and changes in other hemodynamic parameters such as cardiac index (CI), in patients with AMI-CS and tachycardia. Materials and methods. A single-center, open label, randomized clinical trial included patients diagnosed with AMI-CS and tachycardia with >100 beats per minute (BPM). Heart rate, cardiac index, and other hemodynamic parameters measured by pulmonary flotation catheter were compared at 0, 6, 12, 24, and 48 hours after randomization. Re...