Introduction. Liver cancer is the seventh most common neoplasm worldwide and the second cause of mortality directly associated with cancer. In Mexico it has an incidence of 3.9% in the entire population. Although computed tomography (CT) is the imaging study of choice, the final diagnosis is established with the anatomopathological study of the lesion. Objective. Correlate the tomographic findings with the histopathological result in patients with liver lesions with suspicion of malignancy, who underwent USG-guided biopsy. Methods. Descriptive, correlation, retrolective, homodemographic and single-center study. The study period was from September 2021 to February 2022. Patients older than 18 years with liver lesions suspicious of malignancy were selected and underwent Computed Axial Tomography and ultrasound-guided biopsy. Shapiro Wilk tests (for normality) were used and chi-square was u...

Objective: To compare the effectiveness of stratifying high cardiovascular disease (CVD) risk inpatients diagnosed with rheumatoid arthritis (RA) using the Framingham Risk Score (FRS), modifiedSystematic Coronary Risk Evaluation (mSCORE), 2013 American College of Cardiology/AmericanHeart Association (2013 ACC/AHA) guidelines and QResearch Risk Estimator version 3 (QRISK3),with carotid ultrasound (CUS) serving as the gold standard for detecting subclinical atherosclerosis.Materials and methods: A comparative, observational and cross-sectional diagnostic study was conducted in patients aged 40 to 75 years, of both sexes, with RA and without CVD, at a tertiarycare hospital in Puebla, Mexico. Patients on treatment with one or more disease-modifying antirheumatic drugs (DMARDs) for at least three months were included. Patients with chronic diseases and those who did not undergo a CUS were exc...

Introduction: Transplantation is the treatment of choice in patients with chronic kidney disease (CKD). It requires immunosuppression, which predisposes to the development of complications. Chronic rhinosinusitis (CRS) is one of the most important. Objective: To compare the characteristics of patients with CKD with and without CRS undergoing renal transplantation protocol in a concentration Hospital in Puebla, Mexico. Methods: Comparative, cross-sectional, retrospective study in patients in a tertiary care hospital with CKD and undergoing renal transplantation protocol. The SNOT-22 and Lund-Mackay scales were applied. Descriptive statistics and Mann-Whitney U test, Fisher's exact test and Phi coefficient were used; p<0.05 was considered significant. Results: 360 patients were recruited, 49 presented CRS, prevalence: 13.61%. Means: age: 39.22 ±12.09 years and evolution time: 17.73 ±5...

Vascular malformations represent a heterogeneous spectrum of lesions that often present a diagnostic and therapeutic challenge, thus requiring a high index of clinical suspicion to reach a definitive diagnosis. Cloves syndrome is a rare overgrowth disorder of genetic etiology associated with a somatic activating mutation in PIK3CA, which is part of the PI3KAkt-mTOR intracellular signaling pathway. Clinically, it is characterized by congenital lipomatous overgrowth of any part of the body (mainly the thorax), accompanied by vascular and lymphatic malformations, epidermal nevi and structural abnormalities of the skeletal system such as scoliosis and alterations in the spine. The current therapeutic cornerstone for this syndrome is therapy with rapamycin, an mTOR pathway inhibitor. On the other hand, Klippel-Trenaunay syndrome is a complex vascular condition associated with overgrowth due t...