La investigación se realizó con el objetivo de determinar el efecto de Pseudomonas spp. con diferentes dosis de fertilizante químico en el desarrollo de Zea mays L. ―maíz‖. En 15 cultivos bacterianos previamente aislados de la rizósfera de Asparagus officinalis L. se verificaron in vitro promoción de crecimiento vegetal. En el primer ensayo, bajo un diseño completamente aleatorio (DCA), se investigó el efecto de estas bacterias en la emergencia, altura, biomasa aérea y longitud radicular del maíz. En el segundo ensayo bajo un DCA con arreglo factorial, se determinó el efecto de tres dosis de fertilizante químico (0, 50, 100%) y cinco Pseudomonas spp. (1, 2, 3, 4, 5) en el crecimiento y rendimiento de maíz. Los 15 cultivos de Pseudomonas spp. produjeron ácido indol acético, fijaron nitrógeno, solubilizaron fosfato tricálcico e incrementaron la altura y longitud de la ...

Persistent bacteria are the transient variants of a genetically homogeneous population generated by exposure to stress as in antibiotic treatment. They are an epigenetic phenomenon or a non-inherited phenotype, which may be considered as the first line of defense before developing antimicrobial resistance. Despite their discovery more than 70 years ago, their definition, mechanisms of formation, classification and morphologies of clinical implication are still current research topics. In the present research, we describe the relationship between chronic persistent infections and the formation of biofilms as important factors in recurrences, relapses and greater virulence in infections. Likewise, a brief review of the various mechanisms involved in bacterial persistence, their ineffective elimination due to antibiotic tolerance, and possible treatment strategies is provided. Overall, it i...

Introduction: Measles is one of the most contagious diseases that affect humans. After its eradicationin the Americas region in 2016, it has reemerged and the number of cases is progressively increasing..Objective: To deepen and update the most important aspects of the measles virus molecularepidermiology in the Americas. Methods: The search and analysis of the information was carriedout over a period of five months (November 1, 2019 to March 31, 2020) for which the following wordswere used: measles, molecular epidemiology, America, outbreak, genotype, epidemic, in the PubMed,Hinari, SciELO and Medline databases Likewise, the epidemiological reports of the Pan American HealthOrganization (PAHO) and government entities from different countries of America were taken intoaccount. Results: Two lineages of the D8 genotype are spreading widely in the Americas region. Andalthough we still canno...

Introduction: Measles is one of the most contagious diseases that affect humans. After its eradicationin the Americas region in 2016, it has reemerged and the number of cases is progressively increasing..Objective: To deepen and update the most important aspects of the measles virus molecularepidermiology in the Americas. Methods: The search and analysis of the information was carriedout over a period of five months (November 1, 2019 to March 31, 2020) for which the following wordswere used: measles, molecular epidemiology, America, outbreak, genotype, epidemic, in the PubMed,Hinari, SciELO and Medline databases Likewise, the epidemiological reports of the Pan American HealthOrganization (PAHO) and government entities from different countries of America were taken intoaccount. Results: Two lineages of the D8 genotype are spreading widely in the Americas region. Andalthough we still canno...

The current Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic has severely impacted the economy and health care system in more than 180 countries around the world in an unprecedented event, which since its inception has resulted in countless case reports focusing on the potentially fatal systemic and respiratory manifestations of the disease. However, the full extent of possible neurological manifestations caused by this new virus is not yet known. Understanding the interaction of SARS-CoV-2 with the nervous system is essential to assessing likely short- and long-term pathologic consequences. This review seeks to gather and discuss evidence on the occurrence of neurological manifestations and/or nervous system involvement in SARS- CoV-2 infected patients.

The current Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic has severely impacted the economy and health care system in more than 180 countries around the world in an unprecedented event, which since its inception has resulted in countless case reports focusing on the potentially fatal systemic and respiratory manifestations of the disease. However, the full extent of possible neurological manifestations caused by this new virus is not yet known. Understanding the interaction of SARS-CoV-2 with the nervous system is essential to assessing likely short- and long-term pathologic consequences. This review seeks to gather and discuss evidence on the occurrence of neurological manifestations and/or nervous system involvement in SARS- CoV-2 infected patients.

The global spread and lethality of SARS-CoV-2 prompt the urgent need to develop an appropriate therapeutic strategy to control COVID-19 cases. The development of new drugs to fight this novel virus is urgent due to its rapid spread. Parallel alternatives have been proposed by using drugs already available for similar purposes. This review article describes theantiviral potential of ivermectin as well as its mechanisms of action against some viruses, and discusses its probable use to fight SARS-CoV-2.

Background: The genetic variability of SARS-CoV-2 has increased notably since the pandemic was declared, which has allowed it to represent a continuous challenge for health policies aimed at its control. Objective. Describe the genomic nomenclature used for general and scientific communication about SARS-CoV-2, as well as describe the mutations, evolution, origin and variants of the virus. Material and Methods. A narrative literature review was carried out, for which a search and analysis of the information was carried out until December 15, 2021. 74 sources selected from the MEDLINE / PubMed, SciELO, LILACS databases and official web pages were reviewed; no language restrictions. Results. Mutations are changes in the nucleotide sequence of the viral genome, which, by affecting the epidemiological dynamics in a population, give rise to variants, and these in turn to differentiated clades...

background: Monkeypox is a viral zoonotic disease caused by the poxvirus of the same name, endemic to central and western Africa. However, its presence has increased in other regions of the world during the last decade compared to the previous 40 years. Objective. To describe and update the etiologic, epidemiologic, and clinical features of simian pox, as well as to discuss the potential risk of international spread. Material and Methods. A review of literature published in the last five years was performed using the descriptors Medical Subject Headings. The search was performed in the MEDLINE/PubMed and LILACS databases, without language restrictions. Duplicate studies and those that did not fit the research objective were excluded, selecting 47 articles. Results. Simian smallpox virus is related to human smallpox virus (eradicated in 1979). It is transmitted from a sick individual by r...

“Introducción: Las Enterobacteriaceae productoras de betalactamasas de espectro extendido están presentes en las heces de los individuos de la comunidad. En Perú, la automedicación, el tipo de alimentación, condiciones sanitarias podrían asociarse a esta colonización. Objetivo: determinar la frecuencia de colonización rectal por EP-BLEE en pacientes de consulta externa del Hospital Regional Lambayeque, así como los factores asociados a la misma, durante los meses de julio 2018 a febrero 2019. Material y método: 331 pacientes participantes fueron entrevistados, de los cuales se obtuvieron tres muestras seriadas de heces recién emitidas. Las muestras fueron cultivadas en agar McConkey. Las EP-BLEE se confirmaron con la prueba de disco combinado (método americano). Resultados: el 85,8 % de los pacientes estuvieron colonizados por EP-BLEE, siendo Escherichia coli el aislamiento...

“Introducción: Las Enterobacteriaceae productoras de betalactamasas de espectro extendido están presentes en las heces de los individuos de la comunidad. En Perú, la automedicación, el tipo de alimentación, condiciones sanitarias podrían asociarse a esta colonización. Objetivo: determinar la frecuencia de colonización rectal por EP-BLEE en pacientes de consulta externa del Hospital Regional Lambayeque, así como los factores asociados a la misma, durante los meses de julio 2018 a febrero 2019. Material y método: 331 pacientes participantes fueron entrevistados, de los cuales se obtuvieron tres muestras seriadas de heces recién emitidas. Las muestras fueron cultivadas en agar McConkey. Las EP-BLEE se confirmaron con la prueba de disco combinado (método americano). Resultados: el 85,8 % de los pacientes estuvieron colonizados por EP-BLEE, siendo Escherichia coli el aislamiento...

Background: Extended-spectrum beta-lactamase-producing Enterobacteriaceae (EP-BLEE) are present in the feces of individuals in the community. In Peru, self-medication, type of diet and sanitary conditions could be associated with this colonization. Objective: to determine the frequency of rectal colonization by EP-BLEE in outpatients of the “Hospital Regional Lambayeque”, as well as the factors associated with it, during the months of July 2018 to February 2019. Material and methods: 331 participating patients were interviewed, and three serial samples of freshly emitted stool were obtained from them. The samples were cultured on McConkey agar. EP-BLEE were confirmed with the combined disc test (American method). Results: 85.8% of patients were colonized by EP-BLEE, and Escherichia coli was the most frequent isolate (87.7%). Bivariate analysis associated the consumption of pork (RP=1...