The current Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic has severely impacted the economy and health care system in more than 180 countries around the world in an unprecedented event, which since its inception has resulted in countless case reports focusing on the potentially fatal systemic and respiratory manifestations of the disease. However, the full extent of possible neurological manifestations caused by this new virus is not yet known. Understanding the interaction of SARS-CoV-2 with the nervous system is essential to assessing likely short- and long-term pathologic consequences. This review seeks to gather and discuss evidence on the occurrence of neurological manifestations and/or nervous system involvement in SARS- CoV-2 infected patients.

The current Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic has severely impacted the economy and health care system in more than 180 countries around the world in an unprecedented event, which since its inception has resulted in countless case reports focusing on the potentially fatal systemic and respiratory manifestations of the disease. However, the full extent of possible neurological manifestations caused by this new virus is not yet known. Understanding the interaction of SARS-CoV-2 with the nervous system is essential to assessing likely short- and long-term pathologic consequences. This review seeks to gather and discuss evidence on the occurrence of neurological manifestations and/or nervous system involvement in SARS- CoV-2 infected patients.

The global spread and lethality of SARS-CoV-2 prompt the urgent need to develop an appropriate therapeutic strategy to control COVID-19 cases. The development of new drugs to fight this novel virus is urgent due to its rapid spread. Parallel alternatives have been proposed by using drugs already available for similar purposes. This review article describes theantiviral potential of ivermectin as well as its mechanisms of action against some viruses, and discusses its probable use to fight SARS-CoV-2.

background: Monkeypox is a viral zoonotic disease caused by the poxvirus of the same name, endemic to central and western Africa. However, its presence has increased in other regions of the world during the last decade compared to the previous 40 years. Objective. To describe and update the etiologic, epidemiologic, and clinical features of simian pox, as well as to discuss the potential risk of international spread. Material and Methods. A review of literature published in the last five years was performed using the descriptors Medical Subject Headings. The search was performed in the MEDLINE/PubMed and LILACS databases, without language restrictions. Duplicate studies and those that did not fit the research objective were excluded, selecting 47 articles. Results. Simian smallpox virus is related to human smallpox virus (eradicated in 1979). It is transmitted from a sick individual by r...

Se realizó la presente investigación para evaluar el efecto antibacteriano in vitro del extracto etanólico de Cucurbita moschata Duch. “loche” frente a Escherichia coli, Shigella sp., Salmonella enterica y Vibrio cholerae. Así como para evaluar la acción antihelmíntica in vivo del extracto acuoso de Cucurbita moschata Duch. “loche” contra Syphacia obvelata (oxiuros) e Hymenolepis nana var. fraterna. La actividad antibacteriana se determinó mediante Disco difusión donde se enfretnaron las bacterias mencionadas a concentraciones del 100, 75, 50 y 25% del extracto etanólico, mientras que los parásitos se mantuvieron en ratones Mus musculus a los que se les aplicó el extracto acuoso. Se encontró que Cucurbita moschata Duch. carece de actividad antibacteriana, así como contra H. nana var. fraterna, pero posee una muy eficaz actividad antihelmíntica.

Background: The genetic variability of SARS-CoV-2 has increased notably since the pandemic was declared, which has allowed it to represent a continuous challenge for health policies aimed at its control. Objective. Describe the genomic nomenclature used for general and scientific communication about SARS-CoV-2, as well as describe the mutations, evolution, origin and variants of the virus. Material and Methods. A narrative literature review was carried out, for which a search and analysis of the information was carried out until December 15, 2021. 74 sources selected from the MEDLINE / PubMed, SciELO, LILACS databases and official web pages were reviewed; no language restrictions. Results. Mutations are changes in the nucleotide sequence of the viral genome, which, by affecting the epidemiological dynamics in a population, give rise to variants, and these in turn to differentiated clades...