We have taken as data for the statistical study of 26 consecutive observations weight of newborn and placenta in Lima (150 m.) And 29 in Cerro de Pasco (4,200 m.). Sibien studying the technical data of the randomized comparison of two groups showed no significant difference between placental weights, covariance analysis indicates that increasing the height influence placental weight significantly (F <0.001), in while the weight of the newborn becomes smaller.

We have studied the urinary excretion of estrogens in 15 normal term pregnant women by the method of gas chromatography and thin layer Wotiz and Chottoraj, with the following results: Estrone. 1.90 + 0.73 mgm / 24 hours Estradiol: 0.56 ± 0.20 mgm. / 24 hours. Estriol: 27.2 + 9.2 mgm / 24 hours.. (Average ± standard deviation). The method is described and the clinical application of the findings discussed estrogen during pregnancy. In a case of hydatidiform mole, chorionic gonadotropin high with low estrogen excretion was found, estriol decreased the very being.

The oxygen tensión and acid-bases status of mother and fetus have been studied at delivery in 12 subjects from Lima (150 m.] and Cerro de Pasco (4,200 ,m.), Perú. Despite the low pO2 (60.7 ± 2 mm.Hg., x ± SEM) of maternal arterial blood at altitude, the tension of oxygen measured in microsamples of arterialized capillary blood from the fetal scalp was similar at altitude (19.0 ± 1.16 mm.Hg.) and sea level (21.5 ± 1.12 mm.Hg.). The fetus at altitude is born with a mixed acid-base disturbance that combines a respiratory alcalosis (pCO2 = 29.8 ± 3.4 mm.Hg.) with a metabolic acidosis (base-excess = -7.4 ± 1.6 m.Eq./L) and a pH similar to that found at sea level. The low fetal pCO2 correlotes welI with a decreased maternal pC02, at altitude, due to the additive effects of the hiperventilations of altitude and pregnancy (r = 0.77, p < 0 .001). There is a high degree of correlation betw...

Editorial

We have studied the urinary excretion of estrogens in 15 normal term pregnant women by the method of gas chromatography and thin layer Wotiz and Chottoraj, with the following results: Estrone. 1.90 + 0.73 mgm / 24 hours Estradiol: 0.56 ± 0.20 mgm. / 24 hours. Estriol: 27.2 + 9.2 mgm / 24 hours.. (Average ± standard deviation). The method is described and the clinical application of the findings discussed estrogen during pregnancy. In a case of hydatidiform mole, chorionic gonadotropin high with low estrogen excretion was found, estriol decreased the very being.

We have taken as data for the statistical study of 26 consecutive observations weight of newborn and placenta in Lima (150 m.) And 29 in Cerro de Pasco (4,200 m.). Sibien studying the technical data of the randomized comparison of two groups showed no significant difference between placental weights, covariance analysis indicates that increasing the height influence placental weight significantly (F <0.001), in while the weight of the newborn becomes smaller.

The oxygen tensión and acid-bases status of mother and fetus have been studied at delivery in 12 subjects from Lima (150 m.] and Cerro de Pasco (4,200 ,m.), Perú. Despite the low pO2 (60.7 ± 2 mm.Hg., x ± SEM) of maternal arterial blood at altitude, the tension of oxygen measured in microsamples of arterialized capillary blood from the fetal scalp was similar at altitude (19.0 ± 1.16 mm.Hg.) and sea level (21.5 ± 1.12 mm.Hg.). The fetus at altitude is born with a mixed acid-base disturbance that combines a respiratory alcalosis (pCO2 = 29.8 ± 3.4 mm.Hg.) with a metabolic acidosis (base-excess = -7.4 ± 1.6 m.Eq./L) and a pH similar to that found at sea level. The low fetal pCO2 correlotes welI with a decreased maternal pC02, at altitude, due to the additive effects of the hiperventilations of altitude and pregnancy (r = 0.77, p < 0 .001). There is a high degree of correlation b...

Editorial

El objetivo fue comparar mediante un ensayo prospectivo ciego, la eficacia de lisurida y bromocriptina en la inhibición de la lactancia y niveles de prolactina (PRL). Se evaluaron dos grupos de 25 pacientes que requerían inhibir la lactancia. Las pacientes se asignaron a cada droga en forma alternada. Se realizaron observaciones antes del tratamiento, a las 48 horas y 14 días; evaluando la galactorrea, congestión mamaria y mastalgia con una escala nominal de 4 grados. Se determinó los niveles de PRL por RIA. Las estadísticas nominales se analizaron mediante Chi cuadrado y las cuantitativas con la T de Student. A las 48 horas se obtuvo un alivio muy significativo de los síntomas y signos clínicos y el nivel de PRL se redujo a menos de la mitad de la cifra basal. A los 14 días las pacientes se encontraban asintomáticas y el nivel de PRL se hallaba en el rango normal. Ambas medici...

The two hours pst prandial blood sugar of 209 blood relatives, fifteen years or older, of the diabetic patients from the files at the University Hospital has been studied, as a pilot program in Community Medicine.  Forty seven (22.5%) of the probands had levels of 130 mgm% or more and were unwire considered suspicious of diabetes. Six (2.8%) had 175mg% or more, and were clasified as diabetics.  The search for the probands was done by house visits for one group, and bry motivation at the time of the out-patient visit of the diabetic patient in another. The house visit program gave better results, with a larger number of probands per family studied. The major obstacle to the house visit program was inadecuate recording of the patients address at the hospital files. The advantages of the house visit program, and the importance of the detection of diabetes as a medical program dire...

The two hours pst prandial blood sugar of 209 blood relatives, fifteen years or older, of the diabetic patients from the files at the University Hospital has been studied, as a pilot program in Community Medicine.  Forty seven (22.5%) of the probands had levels of 130 mgm% or more and were unwire considered suspicious of diabetes. Six (2.8%) had 175mg% or more, and were clasified as diabetics.  The search for the probands was done by house visits for one group, and bry motivation at the time of the out-patient visit of the diabetic patient in another. The house visit program gave better results, with a larger number of probands per family studied. The major obstacle to the house visit program was inadecuate recording of the patients address at the hospital files. The advantages of the house visit program, and the importance of the detection of diabetes as a medical program dire...

La normativa de contrataciones y adquisiciones del Estado regula, entre otras cosas, los contratosde obra pública en el Perú. Así, estos se encuentran establecidos como contratos de prestaciones recíprocas entre las partes, en las cuales convergen, tanto la ejecución de la obra realizada por el contratista, como el pago por la retribución realizada de parte de la entidad pública. En el presente artículo, los autores explican los conceptos relacionados al contrato de obra pública, recogiendo para tal fin aspectos considerados en la doctrina general que no se encuentran establecidos en una norma expresa, tales como el Equilibrio Económico - Financiero del contrato y los elementos que distorsionan tal balance. Del mismo modo, se desarrollan las modalidades de ejecución de los contratos de obra, entre los que se encuentran, el concurso oferta y la modalidad llave en mano.