Objective: To determine the prevalence of obstructive sleep apnea (OSA), as confirmed byrespiratory polygraphy, and to analyze its association with sociodemographic, anthropometric, lifestyle, and comorbidity-related variables among patients attending outpatient pulmonary consultations. Materials and methods: An observational, analytical, and retrospective study was conducted based on the medical records of adult patients evaluated for suspected OSA at the Pulmonology Department of Hospital de Especialidades No. 2, a tertiary care center of the Instituto Mexicano del Seguro Social (IMSS – Mexican Social Security Institute) in Ciudad Obregón, Sonora, between January 2023 and December 2024. Patients who had undergone respiratory polygraphy and had recorded variables such as age, sex, weight, height, body mass index (BMI), neck and abdominal circumference, physical activity, smoking hist...

Studies of Native South American genetic diversity have helped to shed light on the peopling and differentiation of the continent, but available data are sparse for the major ecogeographic domains. These include the Pacific Coast, a potential early migration route; the Andes, home to the most expansive complex societies and to one of the most widely spoken indigenous language families of the continent (Quechua); and Amazonia, with its understudied population structure and rich cultural diversity. Here, we explore the genetic structure of 176 individuals from these three domains, genotyped with the Affymetrix Human Origins array. We infer multiple sources of ancestry within the Native American ancestry component; one with clear predominance on the Coast and in the Andes, and at least two distinct substrates in neighboring Amazonia, including a previously undetected ancestry characteristic...