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We have recently read the article by Chaung et al1 describing a case of SARS‐CoV‐2 and HCoV‐HKU1 coinfection. The HCoV‐HKU1 is also a member of the Betacoronavirus. In addition to other coronaviruses in different regions of the world, there is an increasing number of reports of coinfections in SARS‐CoV‐2/COVID‐19. Then, we would like to take the opportunity to discuss some of them,1-10 as there are not yet reviews on this emerging issue of COVID‐19. Currently, the evidence suggests that the coinfection rates between SARS‐CoV‐2 and other respiratory pathogens would be higher than initially expected, which represents a challenge for the diagnosis and treatment.

Letter to the Editor (without abstract)

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Objective: Develop a narrative synthesis about a global public health problem known as psychostimulant misuse. Materials and methods: Narrative literature review using six databases from January 2010 to December 2023, under PRISMA recommendations. Results: The psychostimulants consumption, including nootropics and energy drinks, is increasing worldwide, creating a public health problem. Substances such as methylphenidate, modafinil and piracetam are used without a prescription to improve academic and work performance, as well as energy drinks, led by caffeine. The increase in their production and consumption has been associated with adverse cardiovascular and neurological effects. Conclusion: The indiscriminate consumption of psychostimulants has been associated with adverse cardiovascular and neuropsychiatric effects, so scientific and political interest should be encouraged in the cons...

Objetivo: Describir características microbiológicas de las infecciones en pacientes pediátricos con cáncer en un centro de referencia del Eje Cafetero Colombiano 2014 – 2016. Materiales y métodos. Estudio descriptivo, corte transversal de pacientes oncológicos menores de 18 años hospitalizados en una institución de referencia en Colombia; los cuales hayan presentado una infección y se les haya realizado un cultivo con antibiograma. La ficha de recolección validada por expertos es reportada a través de WHONET 5.6. Análisis estadísticos descriptivos fueron realizados con STATA 14.2, versión oficial. Resultados. 2691 cultivos de 596 pacientes fueron incluidos. 53,86% correspondió a sexo masculino, la edad media fue de 8,86 años. El 76,89% de los cultivos se realizaron en el área de hospitalización. El 74,36% de los cultivos fueron de sangre, con un 22,04% de reportes pos...

Immunization is one of the most important advances in medicine, achieving protection against numerous microorganisms that have put the health of the population at risk for centuries and is currently one of the main health prevention strategies; Recently, with the appearance of COVID-19, a before and after has been marked, since vaccination has regained visibility and importance after the pandemic. However, despite the available evidence, there is limited dissemination and promotion of vaccination in the adult, a situation that generates low coverage in this population. The current global context sets an urgent call to strengthen the implementation of vaccination plans and strategies not only in the pediatric population, but also in the adult population, so the objective of this narrative review is to synthesize the current recommendations for vaccination in the population. from Colombia ...

Objective: To develop a narrative synthesis on polycythemia, a prevalent condition that poses diagnostic challenges in primary health care. Materials and methods: A non-systematic literature review was conducted using six databases (PubMed, SCOPUS, ScienceDirect, SciELO, Redalyc, and Google Scholar), covering publications from January 2005 to December 2024. Result: Polycythemia is an underdiagnosed blood hyperviscosity condition with high prevalence and a strong association with cardiovascular events, particularly in cases of polycythemia vera and chronic obstructive pulmonary disease. Conclusion: This review provides a practical approach for early etiological diagnosis and timely treatment of polycythemia. The proposed algorithm optimizes resource use in primary care and may reduce diagnostic delays, improving clinical decision-making.

Objective. The objective of the study was to explore predictive variables of mortality in patients with COPD in Colombia. Materials and methods. Case-control study, in adult patients, diagnosed with COPD, treated at the clínica Comfamiliar, Risaralda, from January 1, 2015 to December 31, 2018. Deceased patients were called cases, and the control group was survivors. A data collection instrument validated by expert judgement was used. A multivariate logistic regression analysis was performed, followed by post-modeling analysis for validation. The analyzes were carried out in Stata 14, official version. It was considered significant with p value <0.05. The project was approved by the bioethics committee of the clínica Comfamiliar. Results. 230 patients with a diagnosis of COPD were included. The mortality rate was 10%, for which there were 23 cases. In the multivariate analysis, the p...

Objective: tcompare the decrease in pain in patients with pregabalin therapy versus interventional blocks. Materials and methods: retrospective cohort study that included patients older than 18 years diagnosed with neuropathic pain from a reference center in Pereira, Colombia, between the years 2010-2016. The outcome was assessed at three months in each cohort and was defined as the change in pain intensity according to the visual analog pain scale. The comparison between cohorts and the effectiveness of the intervention was evaluated through repeated measures analysis with the generalized estimating equation. Results: a total of 1451 patients with pain were selected, of these, only 94 met the inclusion criteria. Sixty-two (66%) patients received a pharmacological scheme with pregabalin, and 32 patients (34%) underwent blockages. The pain intensity prior to pregabalin treatment was 7.3 �...

Durante las últimas décadas, el mundo se ha expuesto a una serie de amenazas por brotes virales emergentes de diferente índole, los cuales, sólo al estudiarlos en detalle, surge la posibilidad de comprender su verdadero impacto, no sólo de forma inmediata, si no también, a largo plazo.

Durante las últimas décadas, el mundo se ha expuesto a una serie de amenazas por brotes virales emergentes de diferente índole, los cuales, sólo al estudiarlos en detalle, surge la posibilidad de comprender su verdadero impacto, no sólo de forma inmediata, si no también, a largo plazo. Recientemente, el 12 de diciembre de 2019, la Comisión Municipal de Salud de Wuhan, en la República Popular de China, hizo público un reporte de 27 casos humanos quienes cursaron con una neumonía viral, de los cuales 7 pacientes se encontraban en condiciones críticas, la cual tenía como etiología un nuevo patógeno humano con alta capacidad zoonótica, conocido provisionalmente como Coronavirus novel 2019 (2019-nCoV), y unas semanas después como Enfermedad por Coronavirus 2019 (COVID-19) causada por el virus SARS-CoV-2.

Durante las últimas décadas, el mundo se ha expuesto a una serie de amenazas por brotes virales emergentes de diferente índole, los cuales, sólo al estudiarlos en detalle, surge la posibilidad de comprender su verdadero impacto, no sólo de forma inmediata, si no también, a largo plazo. Recientemente, el 12 de diciembre de 2019, la Comisión Municipal de Salud de Wuhan, en la República Popular de China, hizo público un reporte de 27 casos humanos quienes cursaron con una neumonía viral, de los cuales 7 pacientes se encontraban en condiciones críticas, la cual tenía como etiología un nuevo patógeno humano con alta capacidad zoonótica, conocido provisionalmente como Coronavirus novel 2019 (2019-nCoV), y unas semanas después como Enfermedad por Coronavirus 2019 (COVID-19) causada por el virus SARS-CoV-2.