Determina el efecto del esferificado de la suspensión de harina de tocosh de Solanum tuberosum (Papa) sobre el tejido gástrico dañado por etanol en ratas. Realiza un estudio experimental puro, con un grupo control y post-prueba en el Centro de Investigación de Bioquímica y Nutrición Alberto Guzmán Barrón, Facultad de Medicina, UNMSM. Utiliza como material biológico esferificado de la suspensión de harina de tocosh de papa (ESHTP) y ratas Rattus novergicus. Se emplearon 36 ratas machos (260 ± 40 g), de tres meses de edad, los cuales fueron distribuidos en seis grupos (n=6). La inducción a injuria con etanol al 70% fue según el método de Robert y col 1979, a dosis de 10 mL/kg vía peroral, tras 24 horas de ayuno. Una hora post injuria, se administraron los siguientes tratamientos por tres días: Grupo I, y III: Agua (10 mL/kg); grupo IV: ranitidina (40 mg/kg); grupo V: ESHTP ...

Introduction: The increase in ultra-processed foods (UPFs) intake has raised concerns about its impact on public health. Prospective observational studies have reported significant associations between higher intake of UPFs and adverse health outcomes. The aim of this study is to determine whether these associations could be confirmed in randomized controlled trials (RCTs). Methods: We conducted a systematic review to analyze the evidence on the effects of UPFs intake on health. A systematic search was conducted in Medline, Embase, Web of Science, Scopus, LILACS, and CENTRAL up to April 22, 2024. RCTs in English, Spanish, and Portuguese evaluating the health effects of interventions to modify UPFs intake were included. The certainty of evidence was determined using the GRADE methodology. Results: Three educational intervention studies and one controlled feeding trial were included, evalu...

Background and purpose: Bioavailability studies and observational evidence suggest that heme iron (HI) may have greater impact on iron status indicators compared with non-heme iron (NHI). This systematic review and meta-analysis aimed to review the current evidence on the effect of the administration of HI compared with NHI for improving iron status in non-hospitalized population groups. Methods: We searched Pubmed, CENTRAL, Scopus, Web of Science, and LILACS from inception to July 2024. There was no language restriction or exclusion based on age or iron status. Only randomized controlled trials comparing HI with NHI were considered. A random-effects meta-analysis was performed to compare the effect of treatments for iron status indicators and total side effects (including gastrointestinal side effects). We measured the certainty of the evidence (CoE) using GRADE assessment. Results: Aft...