El objetivo de este estudio fue determinar la frecuencia de reacciones adversas a fármacos en tuberculosis multidrogorresistente (TB MDR) en pacientes que pertenecen a la provincia Trujillo, periodo 2008-2012 y conocer su comportamiento del mismo. Estudio de farmacovigilancia intensiva, observacional descriptivo y corte transversal; se utilizó la información, registrada en la oficina de epidemiología de la Dirección Regional de Salud, de cuáles son los centros de Salud que han documentado en el Programa de Control de la Tuberculosis (PCT) a pacientes con TB MDR pertenecientes a provincia Trujillo, en el periodo 2008, se acudió a ellos y se evaluaron todas la RAFAs registradas en dichos establecimientos, se utilizó además la base de datos creada por el centro nacional de farmacovigilancia (DIGEMID); para establecer la causalidad de las RAFAs se empleó el algoritmo de decisión b...

Modalidad de obtención de segunda especialidad sin designación de jurado según Oficio N.° 009-2025–OGYT-FMH/USMP

Objetivos: Determinar las características clínico epidemiológicas de pacientes adultos jóvenes con cáncer colorrectal. Materiales y métodos: Se solicitó la información recolectada por la Dirección General de Epidemiología mediante la estrategia de vigilancia en enfermedades no transmisibles durante el periodo 2006-2014. Se calculó la tasa de incidencia ajustada para la edad y un análisis estadístico descriptivo de las variables estudiadas. Resultados: Se reportaron 1261 casos de CCR en pacientes entre 20 a 49 años de edad. El cambio porcentual anual (CPA) en la muestra estudiada para la incidencia presentó un descenso para este periodo de -0,09% (p=0,004). El CPA para los casos de CCR fue de -3,9% en hombres (p=0,009) y -5,22% en mujeres (p=0,014). Se reportaron 640 mujeres y 621 varones. La mayor cantidad de casos de CCR en la población estudiada corresponde al grupo de ...

Objective: To analyze the clinical and angiographic characteristics of patients with coronary ectasia found on coronary angiography. Materials and methods: Descriptive study of patients admitted to the cardiac catheterization laboratory of the Hospital Guillermo Almenara with coronary ectasia, during the years 2012 to 2020. The frequency of coronary ectasia, clinical, angiographic and coronary flow characteristics were determined. Results: 7504 catheterizations were reviewed, and 91 patients were found to have coronary ectasia (1.21%). Of these patients, 71 cases were male (78%), and the mean age was 67.74 ± 9.9 years. The 38.5% of cases were obese or overweight; 39.6% were hypertensive; 11% diabetic; 13.2% smoked; 3.3% had chronic kidney disease and 3.3% had polyglobulia. Sixty-one percent of cases had a diagnosis of acute coronary syndrome, and 24% of cases had high-risk stable angina...

Objetivo: Analizar las características clínicas y angiográficas de pacientes con hallazgo de ectasia coronaria en la coronariografía. Materiales y métodos: Estudio descripitivo de pacientes admitidos a laboratorio de hemodinámica del Hospital Guillermo Almenara con hallazgo de ectasia coronaria, durante el periódo comprendido entre 2012 y 2020. Se determinó la frecuencia de ectasia coronaria, características clínicas, angiográficas y de flujo coronario. Resultados: se revisaron 7504 cateterismos y se halló 91 pacientes con ectasia coronaria (1,21%). De estos, 71 casos fueron varones (78%), y la edad media de 67,74 ± 9,9 años. El 38,5% de casos tuvieron obesidad o sobrepeso; 39,6 % fueron hipertensos; 11% diabéticos; 13,2% fumaban; 3,3% padecían enfermedad renal crónica y un 3,3% poliglobulia. El 61% de casos tuvieron diagnóstico de síndrome coronario ...

Objective: To analyze the clinical and angiographic characteristics of patients with coronary ectasia found on coronary angiography. Materials and methods: Descriptive study of patients admitted to the cardiac catheterization laboratory of the Hospital Guillermo Almenara with coronary ectasia, during the years 2012 to 2020. The frequency of coronary ectasia, clinical, angiographic and coronary flow characteristics were determined. Results: 7504 catheterizations were reviewed, and 91 patients were found to have coronary ectasia (1.21%). Of these patients, 71 cases were male (78%), and the mean age was 67.74 ± 9.9 years. The 38.5% of cases were obese or overweight; 39.6% were hypertensive; 11% diabetic; 13.2% smoked; 3.3% had chronic kidney disease and 3.3% had polyglobulia. Sixty-one percent of cases had a diagnosis of acute coronary syndrome, and 24% of cases had high-risk stable angina...

Rheumatic heart disease is the leading cause of cardiovascular disease in young adults under 25 years of age worldwide, with the highest prevalence in low-income countries. The usual and distinctive finding of rheumatic aggression is mitral stenosis, which leads to serious cardiovascular consequences. International guidelines establish transthoracic echocardiography (TTE) as the diagnostic test for rheumatic heart disease; however, it has limitations in the measurement of planimetry and those inherent to Doppler. Transesophageal 3D echocardiography (TTE-3D) is a new modality that shows realistic images of the mitral valve and has the added value of accurately locating the plane of maximum stenosis and better determining commissural involvement.

La cardiopatía reumática es la causa líder de enfermedad cardiovascular en menores de 25 años en el mundo, con una mayor prevalencia en países de bajos ingresos. El hallazgo habitual y distintivo de agresión reumática es la estenosis mitral, lo cual conlleva a graves consecuencias cardiovasculares. Las guías internacionales establecen la ecocardiografía transtorácica (ETT) como prueba diagnóstica de la cardiopatía reumática; sin embargo, presenta limitaciones en la medición de la planimetría y las inherentes al Doppler. La ecocardiografía transesofágica 3D (ETE-3D) es una novel modalidad que muestra imágenes realísticas de la válvula mitral y que presenta como valor agregado el localizar con precisión el plano de máxima estenosis y determinar mejor el compromiso comisural.

Rheumatic heart disease is the leading cause of cardiovascular disease in young adults under 25 years of age worldwide, with the highest prevalence in low-income countries. The usual and distinctive finding of rheumatic aggression is mitral stenosis, which leads to serious cardiovascular consequences. International guidelines establish transthoracic echocardiography (TTE) as the diagnostic test for rheumatic heart disease; however, it has limitations in the measurement of planimetry and those inherent to Doppler. Transesophageal 3D echocardiography (TTE-3D) is a new modality that shows realistic images of the mitral valve and has the added value of accurately locating the plane of maximum stenosis and better determining commissural involvement.

Objectives. During acute infection by the SARS-CoV-2 virus, myocardial involvement has been demonstrated; it is unknown if cardiovascular sequelae in patients recovered from this infection and if these are associated with global morbidity and mortality. The objective of this study was to compare myocardial deformation in patients recovered from mild SARS-CoV-2 virus infection with healthy controls. Materials and methods. This was a cross-sectional observational study that included 33 subjects recovered from mild SARS-CoV-2 infection, who were diagnosed in the previous three to six months, and 31 healthy volunteers, both groups free of cardiovascular risk factors. The study of myocardial deformation was performed using echocardiography with the speckle tracking modality. Clinical and anthropometric variables were compared. Results. The 2D global longitudinal strain of the left ventricle w...

Objetivos. Durante la infección aguda por el virus SARS-CoV-2 se ha demostrado una afectación miocárdica, se desconoce si existen secuelas cardiovasculares en pacientes recuperados de esta infección y si estas se asocian a un incremento en la morbilidad y mortalidad global. El objetivo de este estudio fue comparar la deformación miocárdica en pacientes recuperados de infección leve por SARS-CoV-2 con controles sanos. Materiales y métodos. Estudio observacional transversal que incluyó 33 sujetos recuperados de infección leve por SARS-CoV-2, quienes fueron diagnosticados en los tres a seis meses previos, y 31 voluntarios sanos, ambos grupos libres de factores de riesgo cardiovascular. El estudio de deformación miocárdica se realizó mediante ecocardiografía con modalidad speckle tracking. Se compararon variables clínicas y antropométricas. Resultados. El strain longitudinal ...

Objectives: To determine structural or functional echocardiographic findings in patients recovered from SARS-CoV-2 infection. Materials and methods: Cross-sectional observational study, which included worker patients of a national COVID hospital, who were studied between 3 to 6 months after the diagnosis of SARS-CoV-2 infection. The echocardiographic examination was carried out systematically and included conventional modalities. Results: 65 cases with CoV-2 infection were included, the average age was 37.7 years, obesity was the most frequent comorbidity (13.8%) and the mild clinical presentation was the one with the highest prevalence (84.6%). The mean diastolic diameter and left ventricular eyection fraction were 42mm and 57%, respectively. Likewise, the mean basal diameter of the right ventricle was 31mm, the shortening fraction was 44%, and the probability of pulmonary hypertension ...

Objetivos: Determinar hallazgos estructurales o funcionales ecocardiográficos en pacientes recuperados de infección SARS-CoV-2. Materiales y métodos: Estudio observacional transversal, que incluyó pacientes trabajadores de un hospital nacional COVID, estudiados entre 3 a 6 meses luego del diagnostico de infección SARS-CoV-2. La exploración ecocardiográfica se desarrolló de forma sistemática e incluyó las modalidades convencionales. Resultados: Se incluyeron 65 casos con infección-CoV-2, la edad promedio fue 37.7 años, la obesidad resultó la comorbilidad mas frecuente (13.8%) y la presentación clínica leve fue la de mayor prevalencia (84.6%). Las medias del diámetro diastólico y la fracción de eyección ventrículo izquierdo fueron 42mm y 57% respectivamente. Así mismo la media del diámetro basal del ventrículo derecho fue de 31mm, de la fracción de acortamiento 44% ...

Objectives: To determine structural or functional echocardiographic findings in patients recovered from SARS-CoV-2 infection. Materials and methods: Cross-sectional observational study, which included worker patients of a national COVID hospital, who were studied between 3 to 6 months after the diagnosis of SARS-CoV-2 infection. The echocardiographic examination was carried out systematically and included conventional modalities. Results: 65 cases with CoV-2 infection were included, the average age was 37.7 years, obesity was the most frequent comorbidity (13.8%) and the mild clinical presentation was the one with the highest prevalence (84.6%). The mean diastolic diameter and left ventricular eyection fraction were 42mm and 57%, respectively. Likewise, the mean basal diameter of the right ventricle was 31mm, the shortening fraction was 44%, and the probability of pulmonary hypertension ...

Objectives. During acute infection by the SARS-CoV-2 virus, myocardial involvement has been demonstrated; it is unknown if cardiovascular sequelae in patients recovered from this infection and if these are associated with global morbidity and mortality. The objective of this study was to compare myocardial deformation in patients recovered from mild SARS-CoV-2 virus infection with healthy controls. Materials and methods. This was a cross-sectional observational study that included 33 subjects recovered from mild SARS-CoV-2 infection, who were diagnosed in the previous three to six months, and 31 healthy volunteers, both groups free of cardiovascular risk factors. The study of myocardial deformation was performed using echocardiography with the speckle tracking modality. Clinical and anthropometric variables were compared. Results. The 2D global longitudinal strain of the left ventricle w...