In this literature review article, the objective is to present recommendations for the systemic and local pharmacological treatment of symptomatic irreversible pulpitis, which is one of the most frequent causes of visits to the dentist in search of a treatment for pain. According to articles found in databases such as PubMed, Cochrane, Science Direct, Google Scholar, in addition to the 2017 consensus of the European Society of Endodontics (all of them with a high level of scientific evidence), premedication with non-steroidal anti-inflammatory drugs increases the rate of success of local anesthesia providing predictable anesthesia, saline solution as an irrigant at 2.5 °C reduces postoperative pain, the prescription of antibiotics is prohibited in biopulpectomies since it does not reduce postoperative pain and NSAIDs are the drugs of choice for the pain control after root canal treatmen...

Surgical treatment of third molars frequently requires a prophylactic antibiotic protocol and pharmacological treatment after surgery. Analyzing these protocols was the objective of this study. For this, electronic searches were carried out in the main databases (PubMed, SciELO, Science and academic institutional repositories of different universities) in which trials, systematic reviews, meta-analyzes, theses and studies of different types were identified. The search was filtered between the period 2016 to 2021 and it was determined that antibiotics such as amoxicillin, amoxicillin/clavulanic acid, are the prophylactic antibiotics of first choice since they stand out for different properties, among them, a significant reduction in the risk of infection (up to a 99.9 %). The purpose of prophylaxis is to prevent the possible development of infectious diseases, as well as to avoid the prol...