La investigación realizada ha permitido establecer una valiosa experiencia que establece un marco para la toma de decisiones estratégicas correctas, permitiendo así a la empresa ser mucho más capaz en la resolución de futuros retos manteniendo su interés hacia las percepciones y necesidades de producción, lo que le permite construir procesos eficientes. El análisis de logros representa un proceso básico para poder mantener la mejora continua, mientras se establecen fuertes lazos entre las diferentes áreas.

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We present a prenatal diagnosis case with false negative result in long term villi culture discordant with short term villi culture showing trisomy 21. We discuss possible causes of discordance in this and similar cases and the best way to proceed to ensure correct diagnosis.

OBJECTIVES: To describe the frequency of chromosome anomalies in spontaneous abortions, the influence of maternal and gestational age, and the application of this knowledge in obstetrical practice, and in future pregnancies management. DESIGN: Descriptive transversal study. SETTING: Genetics Medical Institute, Lima, Peru. MATERIALS: Spontaneous abortions samples recieved for study between 1995 and 2007. INTERVENTIONS: Data of 1088 spontaneous abortions samples were obtained and karyotype, maternal age and gestational age were analyzed. MAIN OUTCOME MEASURES: Karyotype normality or abnormality, maternal age. RESULTS: Karyotype was normal in 332 (30,5%) of the 1088 samples and abnormal in 756 (69,5%). Among chromosomal anomalies, aneuploidy showed a frequency of 60,3%, polyploidy, 16,4%, and X monosomy, 9,5%. Prevalence of aneuploidy rose with maternal age. CONCLUSIONS: Cytogenetic study o...

OBJECTIVES: To describe the frequency of chromosome anomalies in spontaneous abortions, the influence of maternal and gestational age, and the application of this knowledge in obstetrical practice, and in future pregnancies management. DESIGN: Descriptive transversal study. SETTING: Genetics Medical Institute, Lima, Peru. MATERIALS: Spontaneous abortions samples recieved for study between 1995 and 2007. INTERVENTIONS: Data of 1088 spontaneous abortions samples were obtained and karyotype, maternal age and gestational age were analyzed. MAIN OUTCOME MEASURES: Karyotype normality or abnormality, maternal age. RESULTS: Karyotype was normal in 332 (30,5%) of the 1088 samples and abnormal in 756 (69,5%). Among chromosomal anomalies, aneuploidy showed a frequency of 60,3%, polyploidy, 16,4%, and X monosomy, 9,5%. Prevalence of aneuploidy rose with maternal age. CONCLUSIONS: Cytogenetic study o...