Introduction In recent years, the number of malaria cases in native communities from Condorcanqui, Amazonas has considerably increased. Plasmodium vivax malaria is endemic in the region and the re-introduction of P. falciparum was reported in 2019. Methods Here, we compiled and analyzed malaria and COVID-19 data reported by the Regional Direction of Health (DIRESA) during the 2020. Additionally, we performed an odds ratio analysis to evaluate significant associations between COVID-19 symptoms and previous malaria infections. Results In 2020, 1547 malaria (97% were P. vivax) and 5968 COVID-19 cases were reported. Furthermore, 96 patients got COVID-19 after getting a malaria infection. From these, 87 were symptomatic (90.6%), and mostly adults, ages 30 to 59 (62.3%). Also, we found that malaria previous infections represent a risk for the presence of symptoms such as fever, cough, throat p...

La Leishmania braziliensis es la principal especie en el Perú que causa Leishmaniasis cutánea y mucocutánea. La gravedad de sus úlceras se relaciona con una reacción inflamatoria exacerbada, por lo que terapias basadas en el secretoma de células estromales mesenquimales (CEM) podrían ser consideradas. El secretoma de las CEM presenta capacidad regenerativa e inmunomoduladora, la cual, incluso, puede ser potenciada cuando se exponen a diversos estímulos o pretratamientos. En este sentido, el objetivo del presente proyecto fue caracterizar el secretoma de las CEM humanas pretratadas con antígeno soluble de L. braziliensis y evaluar su potencial inmunomodulador. Se trabajó con CEMh de gelatina de Wharton las cuales fueron estabilizadas y caracterizadas según los estándares internacionales. En el pase 4 las células fueron pretratadas con antígeno soluble de L. braziliensis (ASL...

Las células madre mesenquimales humanas (CMMh) derivadas de tejido adiposo tienen características y propiedades que las hacen atractivas para la medicina regenerativa. Para ser llevadas a clínica estas células deben ser cultivadas en condiciones de Buenas Prácticas de Fabricación y los medios químicamente definidos son los ideales para mantener estas condiciones por su composición definida libre de elementos xenogénicos. El objetivo del presente trabajo fue evaluar el medio químicamente definido XANADU como medio de expansión a largo plazo para CMMh en comparación con un medio suplementado con suero fetal bovino (medio control) y un medio comercial químicamente definido (MQD-Comercial). La cinética de crecimiento fue evaluada a lo largo de 8 pases (56 días). La morfología y adherencia al plástico fue evaluada visualmente por microscopía. Se midieron la presencia de marc...

The current COVID-19 pandemic has become a major global public health problem with almost one and a half million cases and tens of thousands of deaths until now. Genetics is playing a leading role in the identification, management and treatment of diseases. This article details the importance of genetics as a science to face the global threat of COVID-19, from different approaches. The contributions that genetics have had and will continue to have in the identification of the new SARS-CoV-2 virus, in the development of new diagnostic techniques, in the prevention of infections and development of severe symptoms, as well as in the design of vaccines and in the proposal and evaluation of treatments for COVID-19.

The current COVID-19 pandemic has become a major global public health problem with almost one and a half million cases and tens of thousands of deaths until now. Genetics is playing a leading role in the identification, management and treatment of diseases. This article details the importance of genetics as a science to face the global threat of COVID-19, from different approaches. The contributions that genetics have had and will continue to have in the identification of the new SARS-CoV-2 virus, in the development of new diagnostic techniques, in the prevention of infections and development of severe symptoms, as well as in the design of vaccines and in the proposal and evaluation of treatments for COVID-19.