La resistencia bacteriana a los antibióticos indica una necesidad urgente de encontrar y desarrollar agentes nuevos a partir de fuentes naturales y el veneno de escorpión proporciona moléculas peptídicas prometedoras para el desarrollo de agentes antibacterianos. En el presente estudio experimental se caracterizó los péptidos del veneno crudo de Hadruroides sp. (escorpión) y se evaluó su actividad antibacteriana frente a Acinetobacter baumannii ATCC19606, Klebsiella pneumoniae ATCC 700603 y Serratia marcescens. Los 115 Hadruroides sp se muestrearon en Jaén y se trabajó con una cepa de A. baumannii, K. pneumoniae y S. marcescens. Para el ordeño se aplicó una descarga eléctrica entre 15 a 20 voltios y caracterizado en su composición proteica y tamaño molecular por espectrofotometría UV, SDS-PAGE y UHPLC-Masas (UHPLC-MS/MS). El veneno, fue fraccionado en columnas de Sephadex...

Introduction In recent years, the number of malaria cases in native communities from Condorcanqui, Amazonas has considerably increased. Plasmodium vivax malaria is endemic in the region and the re-introduction of P. falciparum was reported in 2019. Methods Here, we compiled and analyzed malaria and COVID-19 data reported by the Regional Direction of Health (DIRESA) during the 2020. Additionally, we performed an odds ratio analysis to evaluate significant associations between COVID-19 symptoms and previous malaria infections. Results In 2020, 1547 malaria (97% were P. vivax) and 5968 COVID-19 cases were reported. Furthermore, 96 patients got COVID-19 after getting a malaria infection. From these, 87 were symptomatic (90.6%), and mostly adults, ages 30 to 59 (62.3%). Also, we found that malaria previous infections represent a risk for the presence of symptoms such as fever, cough, throat p...