La histiocitosis de células de Langerhans es un trastorno neoplásico raro de etiología desconocida. Varón de 23 años de edad, no fumador, que consultó por fiebre y síntomas constitucionales; y, las imágenes del tórax mostraron múltiples lesiones nodulares bilaterales. El estudio histopatológico evidenció infiltración de células histiocíticas con S100 (+), CD1a (+), macrófagos intraalveolares CD68(+), confirmando el diagnóstico de histiocitosis pulmonar de células de Langerhans. Fue tratado con corticoides, obteniéndose una respuesta clínica y de imágenes favorable.

Cortical adrenocarcinoma is a rare neoplastic pathology with poor prognosis. It produces hormone hypersecretion, causing fortuitous clinical and disparate findings. We present the case of a 32-year-old female patient admitted to the emergency department for abdominal pain, weight loss and palpable mass. Imaging showed a large heterogeneous mass, dependent on the right adrenal gland, in addition to hypercortisolism not dependent on ACTH. She was treated with surgical resection, radiotherapy and mitotane, evolving positively. An infrequent cause of abdominal pain is evidenced in which clinical suspicion, paraclinical support and imaging findings allowed the optimal diagnostic and therapeutic approach.

 Peripartum cardiomyopathy is a rare form of heart failure characterized by left ventricular systolic dysfunction occurring at the end of pregnancy or in the months following delivery. Its incidence is estimated at 1 in every 1 000 to 4 000 deliveries according to US registries, with a high mortality in the African population. Its exact cause is unknown, but various pathophysiological  theories have been proposed; its diagnosis is based on clinical manifestations and the exclusion of other causes of heart failure and although its prognosis is generally good, a small proportion of women may present with chronic heart failure and thromboembolic complications. We present two cases of peripartum cardiomyopathy that debuted with dyspnea and had a usual course of the disease. We highlight the diagnostic process and therapeutic plan based on the latest available guidelines according t...