La histiocitosis de células de Langerhans es un trastorno neoplásico raro de etiología desconocida. Varón de 23 años de edad, no fumador, que consultó por fiebre y síntomas constitucionales; y, las imágenes del tórax mostraron múltiples lesiones nodulares bilaterales. El estudio histopatológico evidenció infiltración de células histiocíticas con S100 (+), CD1a (+), macrófagos intraalveolares CD68(+), confirmando el diagnóstico de histiocitosis pulmonar de células de Langerhans. Fue tratado con corticoides, obteniéndose una respuesta clínica y de imágenes favorable.

 Peripartum cardiomyopathy is a rare form of heart failure characterized by left ventricular systolic dysfunction occurring at the end of pregnancy or in the months following delivery. Its incidence is estimated at 1 in every 1 000 to 4 000 deliveries according to US registries, with a high mortality in the African population. Its exact cause is unknown, but various pathophysiological  theories have been proposed; its diagnosis is based on clinical manifestations and the exclusion of other causes of heart failure and although its prognosis is generally good, a small proportion of women may present with chronic heart failure and thromboembolic complications. We present two cases of peripartum cardiomyopathy that debuted with dyspnea and had a usual course of the disease. We highlight the diagnostic process and therapeutic plan based on the latest available guidelines according t...