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artículo
Were obtained dried calcium alginate beads of 1 mm diameter. The optimum pH for the biosorption of Cu (II) is between 4.5 and 5. The study of the kinetics of biosorption was determined that the thermodynamic equilibrium is reached after 24 h. The data fit very well with the Langmuir model, and shows that the maximum biosorption is Qmax = 80.6 mg / g.
2
artículo
Were obtained dried calcium alginate beads of 1 mm diameter. The optimum pH for the biosorption of Cu (II) is between 4.5 and 5. The study of the kinetics of biosorption was determined that the thermodynamic equilibrium is reached after 24 h. The data fit very well with the Langmuir model, and shows that the maximum biosorption is Qmax = 80.6 mg / g.
3
artículo
Background AKT pathway activation is implicated in endocrine-therapy resistance. Data on the efficacy and safety of the AKT inhibitor capivasertib, as an addition to fulvestrant therapy, in patients with hormone receptor-positive advanced breast cancer are limited. Methods In a phase 3, randomized, double-blind trial, we enrolled eligible pre-, peri-, and postmenopausal women and men with hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer who had had a relapse or disease progression during or after treatment with an aromatase inhibitor, with or without previous cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitor therapy. Patients were randomly assigned in a 1:1 ratio to receive capivasertib plus fulvestrant or placebo plus fulvestrant. The dual primary end point was investigator-assessed progression-free survival assessed both in the overal...
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artículo
Publicado 2021
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Background: Trichosporon fungaemia (TF) episodes have increased in recent years and mortality rates remain high despite the advances in the management of sepsis. New concepts about its clinical course, treatment and microbiology need to be investigated for the better management of this infection. Objectives: To describe the aetiology, natural history, clinical management and prognostic factors of TF. Methods: TF episodes documented between 2005 and 2018 in 23 South American centres were retrospectively investigated by using a standard clinical form. Molecular identification, antifungal susceptibility testing and biofilm production were also performed. Results: Eighty-eight TF episodes were studied. Patients had several underlying conditions, including haematological diseases (47.7%), post-operative status (34%), solid organ transplants (n = 7, 7.9%), among others. Seventy-three (82.9%) p...