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artículo

Exploring treatment decision-making at diagnosis for children with advanced cancer in low- and middle-income countries

Publicado por
Salek, M, Porter, AS, Maradiege, E, Dolendo, MCJ, Figueredo, D, Geriga, F, Gunasekera, S, Kizyma, R, Nguyen, HTK, Nzamu, I, Raza, MR, Rustamova, K, Sari, NM, Rodriguez-Galindo, C, Graetz, D, Bhakta, N, Kaye, EC, Wise, PH, Hunleth, JM, Friedrich, P, Force, L, Baker, JN

Publicado 2024

Enlace

Purpose: Global childhood cancer survival outcomes correlate with regional contextual factors, yet upfront treatment decision-making for children with advanced or poor prognosis cancer in low- and middle-income countries (LMICs) is not well understood. This study aimed to (1) characterize the landscape of contextual factors that shape physician decision-making at diagnosis for these children in LMICs and (2) describe physician rationales for if/when to offer treatment with non-curative intent, including how they define “poor prognosis” during treatment decision-making. Methods: An international panel of pediatric oncologists practicing in LMICs participated in two focus groups structured for the collaborative generation of factors influencing treatment decision-making, including consideration of non-curative treatment pathways at diagnosis. Thematic analysis of qualitative data was c...