Describe las características demográficas y clínicas en un grupo de pacientes con AR que presentan MEA severas atendidos en el Hospital Nacional Guillermo Almenara Irigoyen (HNGAI). El presente es un estudio descriptivo retrospectivo. La selección de los pacientes se hizo de una base de datos preexistente de 645 pacientes con AR establecida atendidos en el servicio de reumatología del HNGAI entre enero y marzo del 2005, se obtuvo las características demográficas y clínicas de los pacientes que presenten en el curso de su enfermedad una o más MEA severas. Los datos fueron procesados y analizados mediante el programa SPSS versión 13.0. La base de datos previa incluye 645 pacientes con AR, 54 pacientes (8.37%) tienen una o más MEA severas, las más prevalentes fueron escleritis/epiescleritis (4.8%), vasculitis reumatoide (1.9%), serositis (1.2 %), síndrome de Felty (0.3%) y glom...

The mental health of medical students around the world has been affected by the presence of anxiety and depression. According to the World Health Organization, more than 260 million people suffer from anxiety and approximately 300 million people suffer from depression. Objective: To determine the association between anxiety and depression in medical students at Ricardo Palma University during the 2021-II academic year. Materials and Methods: Observational, analytical, cross-sectional and quantitative study. From a population of 2046 medical students from the first to the seventh year of studies, the size of the sample obtained was 110 students. The data obtained was collected through Google Forms. Results: Of the medical students, 85.46% manifested some degree of anxiety and 50% manifested some degree of depression. These pathologies occurred more frequently in the female sex, low socioe...

Introduction: Intraventricular hemorrhage (IVH) affects the subependymal germinal matrix, and usually presents between 3 and 4 days of life. Fifty percent of cases occur on the first day and are diagnosed by cranial ultrasound. Affected neonates may develop neurodevelopmental alterations and even die. Objective: To identify the factors associated with intraventricular hemorrhage in very low birth weight newborns in a Peruvian hospital. Material and Methods: Analytical, case-control study. Information was obtained from virtual medical records and analyzed by descriptive and analytical statistics (chi-square or Fisher's exact test, crude and adjusted OR); a sample calculation and goodness-of-fit test were previously performed. Results: 204 neonates were included (55 cases and 149 controls). The most frequent HIV grades were I and II. In logistic regression, the significantly associated fac...

Background: Self-efficacy for managing chronic conditions assesses the confidence a person has on the ability of successfully perform specific tasks related to a chronic condition in several different situations. Self-efficacy is considered one of the most important modifiable factors in educational interventions that enhance Systemic Lupus Erythematosus (SLE) patients’ mental health status. Low disease self-efficacy is associated with SLE morbidity. Objectives: To determine the association of several domains of self-efficacy for managing chronic conditions and health-related quality of life (HRQoL) in SLE patients.

Background: Self-efficacy for managing chronic conditions assesses the confidence a person has on the ability of successfully perform specific tasks related to a chronic condition in several different situations. Self-efficacy is considered one of the most important modifiable factors in educational interventions that enhance Systemic Lupus Erythematosus (SLE) patients’ mental health status. Low disease self-efficacy is associated with SLE morbidity. Objectives: To determine the association of several domains of self-efficacy for managing chronic conditions and health-related quality of life (HRQoL) in SLE patients.

Introduction. Lupus patients have an increased risk of developing infections due to the disease, use of immunosuppressants and corticosteroids. Objective. To identify the associated factors for serious infections in lupus patients in a national referral hospital. Retrospective, analytical, case-control study in the Rheumatology Service of the Guillermo Almenara Irigoyen National Hospital, Lima, Peru. Methods. The registry of hospitalized patients in the study period was analyzed, the cases were patients in whom the etiology of the first infection developed their hospitalization. Controls were hospitalized lupus patients without infections in the same study period. Variables predisposing to the development of infections were analyzed. Results. 61 patients out of 390 hospitalized developed infections during their hospitalization. 48 developed 1 only infectious event (in 40 an etiology deve...

Objective: To determine the impact of homocysteine levels on damage accrual in systemic lupus erythematosus (SLE) patients. Methods: This longitudinal study was conducted in consecutive patients seen every 6 months at our Rheumatology Department since 2012. Patients with available homocysteine levels and who had at least one subsequent visit were included. Univariable and multivariable Cox regression models were done to determine if homocysteine levels were predictive of damage accrual as per the SLICC Damage Index (SDI). The multivariable model was adjusted for pertinent variables (age at diagnosis, gender, socioeconomic status, disease duration, disease activity (SLEDAI), Framingham score, antimalarial and immunosuppressive drug use, average daily dose, and exposure time to prednisone (PDN)). Results: One hundred forty-five patients were included; their mean (SD) age at diagnosis was 4...

Objective: To determine the impact of homocysteine levels on damage accrual in systemic lupus erythematosus (SLE) patients. Methods: This longitudinal study was conducted in consecutive patients seen every 6 months at our Rheumatology Department since 2012. Patients with available homocysteine levels and who had at least one subsequent visit were included. Univariable and multivariable Cox regression models were done to determine if homocysteine levels were predictive of damage accrual as per the SLICC Damage Index (SDI). The multivariable model was adjusted for pertinent variables (age at diagnosis, gender, socioeconomic status, disease duration, disease activity (SLEDAI), Framingham score, antimalarial and immunosuppressive drug use, average daily dose, and exposure time to prednisone (PDN)). Results: One hundred forty-five patients were included; their mean (SD) age at diagnosis was 4...