Se evaluó la antibiosis de las secreciones laticíferas de plantas nativas amazónicas (Artocarpus altilis “pan de árbol”, Couma macrocarpa “leche caspi”, Croton lechleri “sangre de grado”, Ficus insipida “ojé” y Maquira coriacea “capinuri”, frente a cepas intrahospitalarias de Pseudomonas aeruginosa y Staphylococcus aureus, mediante la técnica de los pocillos, en la cual a las secreciones laticíferas que mostraron actividad se les determinó la CIM y CBM mediante la técnica de macrodilución en tubo. Ninguna de las secreciones laticíferas mostraron actividad frente a las cepas de Pseudomonas aeruginosa; dos de las secreciones laticíferas mostraron actividad frente a las cepas de Staphylococcus aureus; siendo el látex de Croton lechleri el que mostró mayor actividad frente a estas cepas bacterianas con una CIM = 15.63 mg/ml seguido del látex de Couma macroc...

Objectives: Antimicrobial resistant (AMR) Campylobacter is a global health threat; however, there is limited information on genomic determinants of resistance in low- and middle-income countries. We evaluated genomic determinants of AMR using a collection of whole genome sequenced Campylobacter jejuni and C. coli isolates from Iquitos, Peru. Methods: Campylobacter isolates from two paediatric cohort studies enriched with isolates that demonstrated resistance to ciprofloxacin and azithromycin were sequenced and mined for AMR determinants. Results: The gyrA mutation leading to the Thr86Ile amino acid change was the only gyrA mutation associated with fluoroquinolone resistance identified. The A2075G mutation in 23S rRNA was present, but three other 23S rRNA mutations previously associated with macrolide resistance were not identified. A resistant-enhancing variant of the cmeABC efflux pump ...