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1
artículo
Breast cancer (BC) is the most common cancer and leading cause of cancer-related deaths. Recent evidence indicates that a substantial proportion of BC may be caused by viral infections. The presence of high-risk genotypes of human papillomavirus (HPV) has been demostrated in BC and associated with hispotathological features. The aims of this study were to evaluate the prevalence rate of high-risk HPV DNA in BC and clinical features associated to it.
2
artículo
Modulation of immune system has demonstrated tumor response in Gastric Cancer. Tumor infiltrating lymphocytes and microsatellite instability are predictive biomarkers for response to anti-PD-L1 drugs in different malignancies, however, studies confirming it in gastric cancer are lacking. We evaluate the role of infiltrating CD8 lymphocytes over clinicopathological features including clinical stage, H. pylori presence, microsatellite instability and survival in Gastric Cancer.
3
objeto de conferencia
Gastric cancer (GC) is the second most common cancer and first leading cause of cancer-related deaths in Peru. Infection by Helicobacter pylori (HP) and Epstein-Barr virus (EBV) are accepted carcinogenic and infection is widely spread in the Peruvian population. The aims of this study were to evaluate HP and EBV-associated GC (EBVaCG), to assess the prevalence rate and to define the characteristics of Peruvian patients. GC samples were prospectively collected from patients who underwent gastroscopy or surgical resection with no preoperative treatment at INEN between 2015 and 2017. Tumor tissue (T), proximal healthy tissue (P) and distal healthy tissue (D) samples were assessed for HP and EBV by quantitative PCR (qPCR) using specific primers. HP and EBV status were analyzed along with clinicopathologic parameters of the tumor. Kaplan-Meier estimation curves overall survival (OS) was appli...