Introducción: El control no farmacológico de los pacientes hipertensos debe ser evaluado pues ha demostrado ser beneficioso junto con el tratamiento farmacológico. No se conoce como es la autopercepción de consumo de sal en grupos hipertensos peruanos. Objetivo: Determinar la asociación entre percepción de consumo de sal en la dieta e hipertensión arterial en pobladores peruanos. Métodos: Estudio transversal analítico, mediante la entrevista de datos auto-reportados de la percepción de consumo de sal y el diagnóstico de hipertensión arterial, así como otras co-variables de interés. Se estimaron razones de prevalencia (RP) utilizando modelos lineales generalizados, familia Poisson, y usando ciudad como cluster.

Introduction: Non-pharmacological control of hypertensive patients should be evaluated as it has been shown to be beneficial along with pharmacological treatment. It is not known how is self-perception of salt consumption in Peruvian hypertensive groups. Objective: To determine the association between perception of salt consumption in the diet and arterial hypertension in Peruvian residents. Methods: Analytical cross-sectional study, through the interview of self-reported data on the perception of salt consumption and the diagnosis of arterial hypertension, as well as other co-variables of interest. Prevalence ratios (PR) were estimated using generalized linear models, Poisson family, and using the city as a cluster. Results: Of 4263 participants, 63.1% were women and the median age was 42 years. 53.3% said they consumed regular or a lot of salt in their diet. In multiple regression, the...

Introduction: Frontotemporal dementia is an important cause of dementia, and its diagnosis is complex due to the multiple neurocognitive manifestations that patients present. Eating disorders associated with this pathology have been reported, but phagophobia is an atypical manifestation. Case report: We present the case of a 74-year-old adult patient with onset of phagophobia associated with a progressive and significant loss of executive functions, compromised spatial orientation, presenting in parallel a marked compromise in instrumental daily activities, psychotic symptoms, apathy, gait disturbance and sleep problems. Conclusions: It is important that adult and older patients with eating disorders, particularly those who also present cognitive, behavioural and social dysfunction are evaluated to rule out the broad spectrum of frontotemporal dementia, since timely diagnosis and treatme...

Tyrosine kinase inhibitors (TKIs) are the standard treatment for epidermal growth factor receptor mutant (EGFRm) advanced non-small cell lung cancer (NSCLC). Combining TKIs with an angiogenesis inhibitor has shown promise in pre-clinical studies. A systematic search of clinical trials found that combining erlotinib (a first-generation TKI) with bevacizumab or ramucirumab (angiogenesis inhibitors) improved progression-free survival (PFS) in EGFRm advanced NSCLC patients compared to TKI alone. However, no significant benefit in overall survival (OS) was observed in trials. Similar efficacy was seen in patients with specific EGFR mutations. Third generation TKIs were used as second-line therapy for patients with the T790M mutation. The combination treatment was associated with a higher incidence of severe adverse events. Overall, combining erlotinib or another TKI with an angiogenesis inhib...

Determinar la frecuencia de actividad física y su asociación con enfermedades crónicas en los ancianos en once ciudades del Perú. Métodos: se realizó un estudio transversal de datos secundarios; La variable dependiente no fue la realización de la actividad física, las enfermedades crónicas y otras variables fisioantropométricas fueron variables independientes. Para el análisis bivariado y multivariado se utilizaron modelos lineales generalizados. Se consideró un nivel de confianza del 95% y una p <0,05 como estadísticamente significativo. Resultados: De los 1030 adultos mayores, 68% (698) no realizaron actividad física. Al realizar el modelo multivariado se obtuvo para cada año de edad un aumento de frecuencia del 1.5% en la actividad física (RPA: 1.015, IC 95% 1.006-1.024, p = 0.001) por cada centímetro de cintura adicional disminuyó 0.6% en la actividad física (RPA: ...

COVID-19 has led us to take preventive measures, such as social isolation, to reduce the high transmissibility of the disease. This could have affected the mental health of various population groups and the development of resilience as a mitigator. A cross-sectional analytical study was conducted with 700 participants from eight cities. The dependent variables were depression, anxiety, and post-traumatic stress disorder (PTSD). The independent variable was resilience. Generalized logistic regressions were used to identify the associations between the variables. The population consisted mostly of university students (65.0%); the rest of the population was distributed among workers of public or private institutions, housewives, and others (35.0%). High prevalences of anxiety (72.7%), depression (64.1%), and PTSD (15.1%) were found, as well as a median (interquartile range) resilience score...

Introducción: el soporte vital básico (BLS) es un grupo de maniobras que constituyen una herramienta fundamental para salvar vidas. Por lo tanto, el conocimiento sobre BLS tiene que ser parte del plan de estudios en las escuelas de medicina. Objetivo: Evaluar el nivel de conocimiento sobre BLS y evaluar sus factores socioeducativos asociados, en estudiantes de medicina de nueve universidades peruanas. Material y métodos: llevamos a cabo un estudio multicéntrico transversal en 2013 y 2014. Incluimos estudiantes de medicina de nueve universidades en ocho regiones o Perú. Medimos el conocimiento sobre BLS mediante un cuestionario validado, que se basó en las Pautas de la American Heart Association (2010); El conocimiento adecuado se definió como una proporción mínima del 50% de las respuestas correctas. Estimamos los índices de prevalencia ajustados utilizando modelos lineales gen...