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artículo
Publicado 2023
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Case of peritoneal tuberculosis in a 54-year-old woman with a history of type II diabetes mellitus, treated irregularly; who presented a clinical picture of abdominal distension, low weight, hyporexia, and diffuse ascites associated with omental edema. A CA-125 sample was taken with a presumed diagnosis of ovarian cancer, however, pathological studies by laparoscopy reported chronic granulomatous peritonitis of the tuberculoid type with caseous necrosis, referring to peritoneal tuberculosis, which is a rare diagnosis that represents 0 .1–0.5% of all cases of Tuberculosis. Peritoneal tuberculosis should be considered as one of the possible differential diagnoses in cases of patients presenting ascites with elevated serum CA-125 levels. However, to confirm the diagnosis it is necessary to obtain histological evidence that supports the presence of changes compatible with this disease. In ...
2
artículo
Publicado 2024
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Chronic Kidney Disease (CKD) is a progressive condition characterized by structural and functional abnormalities in the kidneys that persist for at least 3 months and are not reversible. With a global prevalence of 11% to 13% and 11% in Peru, CKD is a silent disease that can lead to complications such as anemia due to the shortened lifespan of red blood cells, alterations in iron metabolism, and reduced erythropoietin. The use of sodium-glucose cotransporter type 2 inhibitors (SGLT2 inhibitors) has sparked interest in CKD management. Studies such as DAPA-CKD and EMPA-KIDNEY have shown that SGLT2 inhibitors improve renal and cardiovascular parameters, increasing hemoglobin levels by 0.6 g/dl. This effect is attributed to improved erythropoiesis and efficient iron utilization through hepcidin reduction. Additionally, these inhibitors reduce oxidative stress and improve nitric oxide availab...