Temephos and deltamethrin insecticides have been widely used to control Aedes aegypti in Bagua Grande district, Utcubamba, Amazonas, Peru. For this reason, the enzyme profile related to temephos and deltamethrin resistance in A. aegypti from Bagua Grande were evaluated. To determine the resistance status, bioassays were conducted with temephos using larvae and with deltamethrin using adults. Enzymes profile were evaluated by biochemical assays of αEST, βEST, GSTs, and remaining AChE in survived individuals to selective doses of both insecticides. Esterase patterns of larvae and adults were observed by native-PAGE. The population showed temephos susceptibility, with RR 50 = 3.06 and 83.95% mortality, and deltamethrin resistance with a mortality equal to 1.21%. Enzyme assays revealed highly altered levels of GST and AChE in larvae and altered levels of αEST and highly altered levels of ...

Aedes aegypti is an important vector of tropical diseases like Dengue, Zika, Chikungunya, and Yellow Fever and affects mainly countries located in tropical and subtropical zones, including Peru. Synthetic insecticides are used to control this vector, but they also cause a residual effect on the environment, whereas the vector has developed resistance to these compounds, so there is a current need to search for new control alternatives, such as the use of abundant natural resources. Therefore, this work aimed to evaluate the biocidal activity of extracts and oils from Cymbopogum citratus, Rosmarinus officinalis, and Minthostachys mollis on adult Aedes aegypti, as well as to evaluate their quality parameters. Furthermore, the chemical profile of the three species was assessed by ultra-high-performance liquid chromatography coupled with mass spectrometry (LC-MS/MS). The results showed that ...

La Pseudomonas aeruginosa multirresistente (PAMR) constituye un importante problema de salud pública a nivel mundial, que limita las opciones terapéuticas y aumenta la morbilidad y mortalidad. Este estudio presenta el aislamiento, caracterización molecular y evaluación de la estabilidad de bacteriófagos líticos activos contra cepas de PAMR recuperadas de aguas residuales urbanas en Trujillo, Perú. Se confirmaron dieciséis aislamientos clínicos de PAMR mediante pruebas fenotípicas y bioquímicas, y se evaluó su resistencia frente a 13 antibióticos. Se obtuvieron ocho bacteriófagos líticos, que fueron evaluados en cuanto a viabilidad bajo diferentes temperaturas de almacenamiento (4°C, −30°C, −80°C), temperaturas elevadas (37–47°C), condiciones de pH (3, 7, 9), exposición a radiación UV (5–60 s) y rango de hospedero frente a todos los aislados bacterianos. La ca...