This study investigated the effect of ageing and reduction in ovarian function on whole blood serotonin levels and the effect of the oestrogen replacement in postmenopausal women on blood serotonin levels. Amenorrbeic, natural postmenopausal and ovariectomised women had lower blood serotonin levels than regularly menstruating women. Blood serotonin levels increased after oestrogen replacement in postmenopausal women to values similar to those observed in regularly menstruating women. In ovariec-tomised women, the blood serotonin levels were inversely correlated with age (P < 0.01). In women with different serum oestradiol levels ranging 30–1335 pg/ml, a direct relationship was observed between serum oestradiol levels and whole blood serotonin levels (P < 0.001). It was concluded that whole blood serotonin concentration is reduced during menopause by suppression of ovarian function but ...

OBJETIVOS: Determinar los niveles séricos de prolactina en mujeres a nivel del mar y a gran altura, y la prevalencia de hiperprolactinemia en ambos lugares. MÉTODOS: El estudio incluyó a 303 mujeres normales y 112 mujeres con alguna disfunción reproductiva (anormalidades menstruales, galactorrea o dismenorrea). De ellas, 228 vivían en Lima a 150 m sobre el nivel del mar y 187 vivían en Cerro de Pasco a 4340 m. Las mujeres normales incluían mujeres no embarazadas y embarazadas. Las anormalidades menstruales incluyeron amenorrea, oligomenorrea y polimenorrea. RESULTADOS: Los niveles de prolactina sérica fueron significativamente más bajos en las mujeres no embarazadas y embarazadas que vivían a gran altura que a nivel del mar. La prevalencia de la hiperprolactinemia, la galactorrea y las anomalías menstruales fueron significativamente menores a gran altura que al nivel del mar. ...

We studied 8 women transplanted kidney, who completed 10 pregnancies. All grafts were from living persons and 75% were family. The age of pregnant women ranged between 17 and 33 years. The interval between the graft and the pregnancy was 4 months to 5 years, in 3 cases less than one year. Immunosuppression during pregnancy was performed with prednisone (0.15 to 0.20 mglKgldía) and Azothioprina (1.5 to 2.0 mgldía). The most frequent maternal complications were pregnancy-induced hypertension (7 cases), including one case of eclampsia. It was high incidence of urinary tract infection (3 cases), and hydronephrosis, negative factors in the future of the graft. decreased renal function in 2 cases reversible acute rejection and in 1 case was detected. The delivery was by Caesarean section seven cases, a figure that we consider high and may decrease in the future. Delivery implemented to short...

We studied 8 women transplanted kidney, who completed 10 pregnancies. All grafts were from living persons and 75% were family. The age of pregnant women ranged between 17 and 33 years. The interval between the graft and the pregnancy was 4 months to 5 years, in 3 cases less than one year. Immunosuppression during pregnancy was performed with prednisone (0.15 to 0.20 mglKgldía) and Azothioprina (1.5 to 2.0 mgldía). The most frequent maternal complications were pregnancy-induced hypertension (7 cases), including one case of eclampsia. It was high incidence of urinary tract infection (3 cases), and hydronephrosis, negative factors in the future of the graft. decreased renal function in 2 cases reversible acute rejection and in 1 case was detected. The delivery was by Caesarean section seven cases, a figure that we consider high and may decrease in the future. Delivery implemented to short...