Se revisaron las historias clínicas de 420 pacientes con diagnóstico de cáncer de mama debidamente documentado por la anatomía-patológica en estadío clínico II,III y IV. En todos ellos se realizó al menos una gammagrafía ósea al momento del diagnóstico. En 52 casos se realizaron dosajes séricos de CA 15-3 en algunos casos que lo requerían se administró Samario 153 EDTMP como terapia paliativa del dolor óseo. La presencia de focos secundarios gammagráficos fue de 0/84 casos (0%) en el estadío clínico II, de 54/265 casos (20%) en el III y de 41/91 casos (45%) en el IV. El foco único se presentó en el 6,7% de los casos. De los 52 casos que tuvieron dosaje sérico de CA 15-3 en 7 de ellos se detectó lesiones secundarias óseas, y de éstos, 5 cursaron con elevación del marcador. La gammagrafía ósea mostró en muchos casos la presencia de focos captadores en ubicacione...

The ocurrence of insufficiency fractures in patients with long-standing, rheumatoid arthritis has not been sufficiently emphasized.  Osteoporosis due to rheumatoid arthritis, corticosteroid therapy, contracture and angular deformity of the extremity, combine to predispose to the ocurrence of the insufficiency fractures in these patients. Additionally, the pain and disability caused by the fracture is often attributed to rheumatoid joint involvement, masking the diagnosis of insufficiency fracture. The fracture may not be visible on radiographs near the onset of symptoms, and the bone scanning can help in make an early diagnosis. 

The ocurrence of insufficiency fractures in patients with long-standing, rheumatoid arthritis has not been sufficiently emphasized.  Osteoporosis due to rheumatoid arthritis, corticosteroid therapy, contracture and angular deformity of the extremity, combine to predispose to the ocurrence of the insufficiency fractures in these patients. Additionally, the pain and disability caused by the fracture is often attributed to rheumatoid joint involvement, masking the diagnosis of insufficiency fracture. The fracture may not be visible on radiographs near the onset of symptoms, and the bone scanning can help in make an early diagnosis. 

Five patients with thyroid cancer and thyroidectomy are reported. In the whole body iodine-131 scan they had positive iodine-131 uptake with negative serum thyroglobulin (Tg). In all cases, remnant thyroid cancer tissue was reported in the muscle adjacent to the laryngeal cartilage, which could explain iodine uptake in spite of negative serum Tg. It is recommended to perform a whole body iodine-131 scan when there is a strong suspicion of microscopic cancer tissue in the remnant tissues.

Five patients with thyroid cancer and thyroidectomy are reported. In the whole body iodine-131 scan they had positive iodine-131 uptake with negative serum thyroglobulin (Tg). In all cases, remnant thyroid cancer tissue was reported in the muscle adjacent to the laryngeal cartilage, which could explain iodine uptake in spite of negative serum Tg. It is recommended to perform a whole body iodine-131 scan when there is a strong suspicion of microscopic cancer tissue in the remnant tissues.