El cáncer diferenciado de tiroides (DTC) en la población menor de 18 años es una enfermedad relativamente rara, representa el 1.4-2 % de todas las neoplasias malignas pediátricas, con una tasa de incidencia estandarizada en Perú de 0.4 por 100,000, y con mayor prevalencia en adolescentes a predominio del sexo femenino. Debutan con metástasis a ganglios linfáticos regionales y a distancia, 25% a los pulmones con un predominio del patrón micronodular. Afortunadamente, el DCT muestra una ávida absorción del yodo radioactivo (I-131), con un excelente pronóstico cuando se administra el tratamiento adecuado. No existen estudios prospectivos claros sobre el manejo, la American Thyroid Association (ATA) aborda una serie de pautas; sin embargo, quedan muchas preguntas abiertas sobre el manejo óptimo. / El objetivo es valorar la efectividad del tratamiento con I-131 en pacientes con me...

Five patients with thyroid cancer and thyroidectomy are reported. In the whole body iodine-131 scan they had positive iodine-131 uptake with negative serum thyroglobulin (Tg). In all cases, remnant thyroid cancer tissue was reported in the muscle adjacent to the laryngeal cartilage, which could explain iodine uptake in spite of negative serum Tg. It is recommended to perform a whole body iodine-131 scan when there is a strong suspicion of microscopic cancer tissue in the remnant tissues.

Five patients with thyroid cancer and thyroidectomy are reported. In the whole body iodine-131 scan they had positive iodine-131 uptake with negative serum thyroglobulin (Tg). In all cases, remnant thyroid cancer tissue was reported in the muscle adjacent to the laryngeal cartilage, which could explain iodine uptake in spite of negative serum Tg. It is recommended to perform a whole body iodine-131 scan when there is a strong suspicion of microscopic cancer tissue in the remnant tissues.